A/Prof Samantha Stehbens PhD
@SamStehbens
Everything microtubules, movement and microscopy. ARC Future Fellow @AIBNatUQ & @IMBatUQ (formerly @UCSF Wittmann lab alumni)
Excited to announce…..it’s finally arrived (!!) nature.com/articles/s4155… A big thank-you to my team (particularly @robertr33), co authors & #FutureFellowship funding from @arc_gov_au Importantly- a big shoutout to @drDJVDavid @NatureCellBio for their support. 👇tweetorial 👇…
Buckle in, it is #microtubule cell migration story time! We reveal a new role for microtubules as cellular sensors which detect and respond to compressive forces, enabling movement and ensuring survival in mechanically demanding environments; just like this little guy squeezing…
Exciting news from Naba lab as they just released an updated list of anti-ECM antibodies curated from the #HumanBioMolecularAtlasProgram Organ Mapping Antibody Panels #OMAP and the 9th release of the Human Reference Atlas #HRA. More info here: sites.google.com/uic.edu/matris…
Spatial multi-omics reveals cell-type-specific nuclear compartments | Nature nature.com/articles/s4158…
Here's a tortoise embryo developing inside its egg. Check out our new article in @iScience_CP to learn how molecular and mechanical systems sculpt their intricate head scales 🐢🔬
Super excited that our paper is out. It describes a new mechanism for dealing with tissue crowding that does not involve cell extrusion. nature.com/articles/s4146…
Early diagnosis saves lives. Speak to your GP if you have any of these possible skin cancer symptoms or you're worried about any abnormal areas of skin 🗣 We've partnered with NIVEA Sun for over 12 years to help you enjoy the sun safely ☀ #SkinCancer #SunSafety
🚨 PhD students! The EMBL Australia PhD Course is back and the 2025 program preview is live. Think big science, AI and career insights - all in one epic fortnight. 📅 Applications open until 27 July: bit.ly/3IvyV6H #PhDchat #PhDLife #AusSci #ScienceCareers
Interested in nuclear #mechanobiology? Join us for the first ever @FASEBorg Science Research Conference on the Mechanobiology of the Nucleus #MBNSRC. Submit abstracts by August 31, 2025. Find more information at: events.faseb.org/event/Mechanob… Please share and see you in October!
Brain metastasis: From etiology to ecotypes dlvr.it/TLxJTF
Pan-cancer human brain metastases atlas at single-cell resolution dlvr.it/TLw4ZN
Being a scientist is still the best job in the world. The constant frustrations, all the crap that goes with trying to keep the lab alive and move things forward - it all resets and washes away in those occasional moments when we catch a glimpse of nature revealing something…
Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @MBIsg, and the Dept of Physiology at @NUSingapore in the fall! More about our work on vascular mechanobiology: mechano-medicine-lab.com
Interested in a #postdoc on cardiac #mechanobiology? Our lab has a fully funded position via our recently awarded @HFSP grant to study the biophysical processes that build insect hearts🪲🪰🫀 Come join us @MBIsg for some cool evo-devo-mechanobio work! 👇 mbi.nus.edu.sg/jobs/seeking-p…
Hey everyone - the annual @SocietyMelanoma meeting in beautiful Amsterdam is coming up. Always a fantastic lineup of research spanning basic, translational and clinical. We also have a great trainee "pre-SMR" meeting. Join us! smrcongress.org
📣Abstract submissions for the 11th ISA close on 18th July! The 11th ISA invites you to Lorne, Australia to learn about the latest developments in autophagy research. Speaker slots available for ECRs and PhD students! Register here: isa11.org
SNAP-tag is a widespread tool for labelling protein for bioimaging. An article published in @nchembio presents SNAP-tag2 with increased labelling kinetics and brightness, which translates into a better performance in live-cell super-resolution imaging. go.nature.com/4eARnXz
How do cells link adhesion to protein synthesis? New findings suggest the protein p130Cas forms droplets that bud from focal adhesions and suppress translation, hinting at a novel mechanism for regulating cell state via phase separation. elifesciences.org/articles/96157…
Our July cover (hubs.la/Q03vJ8s50) shows a confocal timelapse imaging of #Celegans one-cell embryo expressing fluorescently labeled plasma membrane, microtubules, chromosomes, and ZEN-4, a plus-end directed kinesin motor protein (hubs.la/Q03vJ8yc0). @Sachin_mitosis
A thread of our new preprint 🧵👇 🤩
Have you ever thought about inflating tissues? Or maybe quickly deflating those inflated tissues? New #EpithelialMechanics pre-print: doi.org/10.1101/2025.0… 🧵with pressure control, multiscale buckling, patterned wrinkling
External strain on the plasma membrane is relayed to the endoplasmic reticulum by membrane contact sites and alters cellular energetics | Science Advances science.org/doi/10.1126/sc…
Interesting! Also #Microtubules control Ect2 localisation to locally regulate Rho activity …. ‘ Ect2..localized rapidly to cortical sites contacted by MT plus-tips, resulting in RhoA activation and enrichment of myosin-regulatory light chain.’elifesciences.org/articles/38968
Thrilled that our newest work led by @AveryTTran, Dr. Wisniewski, and @mistrigr is out today in @NatureMaterials! We show how the cytokinesis proteins Anillin and Ect2 drive RhoA/ROCK/myosin-mediated invasion in confining spaces in vitro and in vivo. doi.org/10.1038/s41563….