Konstantopoulos Lab

@KKLabJHU

Cancer Metastasis | Cell Motility | Bioengineering @ JHU

Johns Hopkins University

Joined October 2019

268Following

803Followers

Pleased to share our latest collaborative work with the @DevreotesLab in @PNASNews. Using optogenetics, we show that both insufficient and excessive Ras activity impair cell motility, underscoring the need for optimal Ras signaling and cortical tension. doi.org/10.1073/pnas.2…

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Panagiotis Mistriotis@mistrigr · Jun 30

🎉After years in the making… our work, @KKLabJHU @AveryTTran, Dr Wisniewski & Dr Kalab, is out in Nature Materials! Anillin & Ect2, best known for their roles in cell division, are repurposed by cancer cells to drive confined migration and extravasation. nature.com/articles/s4156…

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CMBE journal@CMBEjournal · Jun 24

I'm pleased to announce that CMBE now has an impact factor of 5.0! And don't forget, there is no publishing fee.

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Konstantopoulos Lab Retweeted

Lammerding Lab@LammerdingLab · May 12

How do altered levels of lamins and other nuclear envelope proteins contribute to cancer metastasis, and how does this relate to #mechanobiology? Learn more in our recent review by @SarahHenretta now out in @Nature_NPJ - biological physics and mechanics (doi.org/10.1038/s44341…).

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Konstantopoulos Lab@KKLabJHU · May 12

Immense congrats to my amazing postdoc @debanikch for winning the Best Poster Award at the 18th Nano-Bio Symposium at @INBT_JHU ! In just one year, he’s co-led a COCB article doi.org/10.1016/j.ceb.……, a book chapter , and has several more in the pipeline. Well-deserved!

KKLabJHU's tweet image. Immense congrats to my amazing postdoc
@debanikch
for winning the Best Poster Award at the 18th Nano-Bio Symposium at @INBT_JHU ! In just one year, he’s co-led a COCB article doi.org/10.1016/j.ceb.……, a book chapter , and has several more in the pipeline. Well-deserved!

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Konstantopoulos Lab Retweeted

Andrew Holle@ahcells · May 8

Three weeks left until the abstract submission deadline for our joint MBI-MPI #mechanobiology conference this September! @MBIsg @maxplanckpress To early career scientists- be sure to apply for a travel award to present your work! mbi.nus.edu.sg/events/mbiconf…

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Konstantopoulos Lab@KKLabJHU · May 7

Huge congrats to my first-year PhD student, Josiah Power @realjosiahpower on receiving an @NSF GRFP! At just 19 and with a double-major in ChemBE & Biochem, he took 5 doctoral-level courses last fall (vs. the usual 3) and aced them all. Incredible talent and drive- well deserved!

KKLabJHU's tweet image. Huge congrats to my first-year PhD student, Josiah Power @realjosiahpower on receiving an @NSF GRFP! At just 19 and with a double-major in ChemBE &amp; Biochem, he took 5 doctoral-level courses last fall (vs. the usual 3) and aced them all. Incredible talent and drive- well deserved!

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Logue Lab@JeremyLogue1 · Mar 21

Happy to share our latest research article, "The activation of INF2 by Piezo1/Ca2+ is required for mesenchymal-to-amoeboid transition in confined environments," in Current Biology: authors.elsevier.com/a/1koXe3QW8SA2… Graphical abstract:

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Konstantopoulos Lab@KKLabJHU · Feb 27

Excited to share our latest review led by @alice_amitrano & @debanikch! We dive into the mechanisms of confined cell migration, exploring how ion channels, cell cytoskeleton, and fluidic & solid cues drive motility & metabolic reprogramming. Read more: doi.org/10.1016/j.ceb.…

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