Sable Systems International 🐭🐀🧝🏼♀️
@SableSys
Thoughts, visions & revisions from John Lighton PhD, president & CIO of Sable Systems International (=the world's most advanced metabolic measurement systems)
This is exceedingly wild. Using an avian dinosaur as a hard drive.
This is one of the craziest ideas I've ever seen. He converted a drawing of a bird into a spectrogram (PNG -> Soundwave) then played it to a Starling who sung it back reproducing the PNG. Using the birds brain as a hard drive with 2mbps read write speed. youtube.com/watch?si=HMtVd…
Interesting! And by the way, a friendly reminder: our Promethion Core system can easily be adapted to measure energy expenditure in birbs such as zebra finches! news.vanderbilt.edu/2025/07/16/van…
@HenverBrunetta summarized the content in this video: m.youtube.com/watch?v=t1c4kl…
We wrote a thing on mitochondrial coupled versus uncoupled respiration 🔥 onlinelibrary.wiley.com/doi/10.1002/bi…
People are fed by the food industry, which pays no attention to health, and are treated by the health industry, which pays no attention to food.
Type 2 diabetes is often considered a protein misfolding disease. But where are these toxic proteins found? 🤔 🚨In new work out today in @NatMetabolism, we show that mitochondrial protein misfolding (yes mitos🤯) leads to beta cell damage in T2D. 🚨 nature.com/articles/s4225… 1/n
Looking to measure #metabolic parameters during #exercise in mice? The Sable Mouse Metabolic Treadmill offers cutting-edge #respirometry technology, enabling rapid, synchronized collection of high-resolution metabolic & behavioral data. ow.ly/i5wk50WuO1J #VO2max #RER #EE
This new preprint was designed so poorly that it provides absolutely no proof that mRNA vaccines caused cancer/other diseases. It compared 10 (!) handpicked sick patients to 803 healthy patients. And behold, they show different RNA expression profiles. Because they were sick.
One of the most-viewed PNAS articles in the last week is “Energy expenditure and obesity across the economic spectrum.” Explore the article here: ow.ly/utv750WuO3x For more trending articles, visit ow.ly/boza50WuO3q.
EXACTLY!
🚨 As agencies discuss the implementation of New Approach Methodologies (NAMs), it’s critical we don’t leave behind what still works. 🧬 Mice are still the gold standard for aging research, offering whole-organism insights, rapid testing, and decades of proven value. 📉…
7 world-changing UC innovations that emerged from federal research funding universityofcalifornia.edu/news/7-world-c…
More promising Promethion‑powered research from Dr. T Bengtsson & colleagues at Karolinska Institutet - GRK‑biased β‑agonists burn fat & lower glucose in obesity models! cell.com/cell/fulltext/…
More fascinating Promethion‑powered science from Dr. J Tam & colleagues at Hebrew University of Jerusalem - blocking renal GLUT2 resets systemic metabolism without hyperglycemia! sciencedirect.com/science/articl…
More groundbreaking Promethion‑powered research from Dr. X Xie & colleagues at Tianjin Medical University - palmitate‑blocked PRDX1 worsens NASH, hinting at redox‑targeted therapy. nature.com/articles/s4146…
A neat new study reveals that the controversial species-energy relationship exists. Temperature 🌡️ directly affects species richness confirming predictions from the MTE, while rainfall 💧 indirectly affects richness through its influence on productivity | doi.org/10.1126/scienc…
Carpe this diem, stat!
Hiya, there is still a few more days left (28th of July) to apply for a @DDEA_Denmark Postdoc grant together with @LykkeSylow and myself! Reach out if you have any questions.
What could possibly go wrong when "...it was revealed that China had launched a targeted campaign particularly designed to lure talented artificial intelligence and other cutting-edge science researchers, and Fast Company reported that the effort was ramped up in April"…
Research reveals that young hearts have a built-in shield against obesity that disappears with age! New research led by Patricia Baumgarten, PhD, and Professor Tilman Grune's lab shows that while young mice stay protected from diet-induced heart failure through remarkable protein…
The Study of Muscle Mobility and Aging (SOMMA) is open for enrollment!! SOMMA is a longitudinal cohort study designed to examine the biological properties of skeletal muscle that predict onset of disability or dementia in older adults. sommaonline.ucsf.edu
I realized we hadn’t cast a wide enough net for this role originally. If you’re a student or recent grad looking to get away from the bench but want to be deeply integrated into a fast-paced research environment with a front row seat into the operations of a new type of science…