Pablo Iván Nikel @pabnik.bsky.social
@PabloINik
Professor @DTUBiosustain · Proud PI @LabNikel · #SynBio · Coordinator @fonia_sin · @F1000 board · @NovoNordiskFond Ascending Investigator · He/him🏳️🌈
Overjoyed & humbled to announce my promotion to Full #Professor & Chair of #Synthetic Bacterial #Metabolism @DTUtweet @DTUBiosustain—I owe this #achievement to the hard work of the amazing @LabNikel bunch, past & current mentors & our collaborators #ProudProfessor #Grateful🎓

When #AlphaFold2 came out, we wondered: Could it help us understand how enzymes evolve? So we tried it—and it worked! nature.com/articles/s4158…
Wrapping up #ME16 #Copenhagen—a success by all measures! Honored to co-chair the meeting w/I. Borodina, M. Chang, A. Mirończuk, C. Vickers, V. Šťovíček, Y. Zhou, M. Köpke & M. Herrgård & to work w/an awesome team of colleagues, engaging communities & topics all around the world

A controversial paper claiming that an extraordinary microorganism can thrive on the toxic element arsenic has been retracted by the journal Science, nearly 15 years after its original publication -- but the paper's authors say the retraction is unwarranted.…
🌱 What makes a climate solution truly sustainable? Do they create fair working conditions? Will they be economically viable in the real world? Discover how life cycle thinking supports biotech innovation 🔗 tolerate-eu-project.com/life-cycle-thi… Thanks to the Omnia team for their contribution!
Enantioselective Pd-catalysed nucleophilic C(sp3)–H (radio)fluorination bit.ly/4nEz7Rc
Come and see us at the #interactive #session led by @cecilia_flocco #FEMS2025 today at 11.30 am if you want to hear about how ancient DNA can drive new-to-Nature #biotechnology & #sustainability
📍 Milan | TODAY! Join Amedea Perfumo & @pabnik.bsky.social at #FEMS 2025 for a dynamic session🧬 "Something (very) old, something new: Innovative microbial solutions for sustainability challenges 🕦 15 July | 11:30–13:00 | Tower Lounge ▶️ youtu.be/0-bhcMpjJ_c
Online now: Systematic engineering of synthetic serine cycles in Pseudomonas putida uncovers emergent topologies for methanol assimilation dlvr.it/TLtMLx
🧬 The language of SEVA expands! The group of @PabloINik use #SEVAplasmids nomenclature in the design of CIFR—a novel iterative transposon tool for genomic engineering of Gam-negative bacteria 👉 doi.org/10.1016/j.ymbe…
🚨 Due to popular demand, the deadline to apply for the @CSHANews course Advanced #SynBio & #Metabolic #Engineering of #Pseudomonas is extended to July 22! #PhD students & #postdocs welcome! 📍Suzhou, China 📅 Sept 7–21 🔗Apply now: csh-asia.org/?content/2642

Implementing synthetic serine cycles in #Pseudomonas putida unlock methanol assimilation in our favorite bug with carbon conservation, led by @OscarPuiggene · #SynBio #MetabolicEngineering #Methanol @TrendsinBiotech sciencedirect.com/science/articl…

The interactions of c-di-GMP with the acidic residues seen in the MshEN domain could be quite widespread onlinelibrary.wiley.com/doi/10.1002/an… Protonated Glutamate and Aspartate Side Chains Can Recognize Phosphodiester Groups via Strong and Short Hydrogen Bonds in Biomacromolecular Complexes
Poster abstract submissions for #SBA2025 are closing on 18th July - get yours in now! See you in Wellington in November #syntheticbiology #synbio #conference @SynBioAusAsia
Very excited to advertise the work of Charli in my lab! biorxiv.org/content/10.110…
Please RT and share! We have up to two PhD positions available in my group for entry in fall 2026, applications expected in fall 2025. DM me if interested!
🚨 Important Update from TOLERATE 🚨 This account will no longer be active. But this is not the end! our work, results and impact will be now shared in our new BluSky account 👍Follow us @tolerateeu.bsky.social 👉 Subscribe to our newsletter eepurl.com/i6uufM
Happy to host @kunjapur as sabbatical #professor @DTUBiosustain supported by Otto Mønsteds Fond! We share a passion for using #SynBio to engineer #microbes with non-natural building blocks for advanced #biotechology. He’s in #Europe—drop a line to connect & discuss cool #Science!

Kilauea Volcano on Hawaii’s Big Island had a massive eruption yesterday….always wild seeing it erupt and knowing people are allowed to get pretty close to one of the most active volcanoes on Earth as it’s spewing a 1,000 foot high lava fountain
ChatGPT now can analyze, manipulate, and visualize molecules and chemical information via the RDKit library. Useful for scientific work across health, biology, and chemistry.
Diets+food systems are driving an ongoing epidemic of overweight/obesity, insulin resistance, diabetes & other diseases ⬇️Fixes are long overdue. See this straightforward 1-stop resource for decision-makers & concerned citizens from @UF_IFAS @UFMedicine doi.org/10.1073/pnas.2…🧵
🆕 New from TOLERATE: What can ancient climates teach us about today’s challenges? Discover how the past helps shape future climate resilience. 🌍 Read more 👉 lnkd.in/dE5CvEfp A special thank you to @AmedeaPerfumo –AWI- for this thoughtful contribution! #TOLERATEProject