SEVAplasmids

The Standard European Vector Architecture (SEVA) platform is an online repository to help #researchers finding the best #plasmid vectors for constructing complex prokaryotic phenotypes. 👩🏾‍🔬 🦠 #synbio

New step in metabolic engineering! A genome editing system for Caldimonas thermodepolymerans develops: ✅ a chassis strain (AI01) with improved transformation efficiency ✅ a mutant (ΔphaC) for polyhydroxyalkanoates synthesis See how: 👉 doi.org/10.1111/1751-7…

#SEVAplasmids for standardisation! In @AngelGMoreno's lab they have used SEVA plasmids for the development of three standardised quorum sensing systems comprising transmitter and receiver modules 👉 doi.org/10.1021/acssyn…

What’s behind pSEVA237M? Each #SEVAplasmid name is a standard which encodes 3 modular elements: 1️⃣ 2 → Kanamycin resistance 2️⃣ 3 → pBBR1 replication origin 3️⃣ 7M → msfGFP cargo And you can add a gadget in position 4️⃣ Find more codes/create yours 👇 seva-plasmids.com

What ways to produce lignans de novo can you think of? Researchers at the @CAS__Science made it by mimicking plant metabolism in a consortium of synthetic yeasts. Find out in detail: 👉doi.org/10.1038/s41589…

🔍Problems with synthetic C1 metabolism? The @PabloINik group identifies seven major barriers limiting its deployment in microorganisms and proposes specific strategies to overcome each of them. Check out their paper 👉doi.org/10.1093/femsre…

📹Got 2 minutes? Meet us in this short video and see how #SEVA helps you do more effective synthetic biology with standardised plasmids👉 youtu.be/I8gZjXDRQ2I?fe…

🔥Bye Crabtree! At @hunanuniv, researchers reprogrammed S. cerevisiae to bypass the Crabtree effect, boosting lactate & 3-hydroxypropionic production by 8-11 times. A major step toward carbon-efficient biomanufacturing 👉nature.com/articles/s4146…

🧬 The language of SEVA expands! The group of @PabloINik use #SEVAplasmids nomenclature in the design of CIFR—a novel iterative transposon tool for genomic engineering of Gam-negative bacteria 👉 doi.org/10.1016/j.ymbe…

Bring your ideas to life with standardised plasmids. You only have to: ✅Remove restriction sites ✅Combine cargos and markers. ✅Send your construct to #SEVA And see how you contribute to reproducible results and efficient scalability. Try it now👇 seva-plasmids.com

New phi15-based expression system in Pseudomonas putida uses #SEVA plasmids for high-yield gene expression. The work by @LabNikel shows how single-copy vectors minimise toxicity, achieve 200×induction, and outperform T7 systems. 👉 nature.com/articles/s4200…

🌊 Researchers at Shenzhen Institutes of Advanced Technology have engineered Vibrio natriegens to degrade five organic pollutants simultaneously! This represents a firm step in bioremediation research. 🔗 nature.com/articles/d4158…

🧬 New tools for gene control! A recent publication highlights ligand-responsive condensates for controlled gene expression in mammalian cells. This modular system can target DNA, RNA, and proteins inside the nucleus.⬇️ nature.com/articles/s4158…

A modular cloning strategy combining Golden Standard and MoClo enabled modular expression of PHB biosynthesis operons in E. coli, achieving notable polymer yields. A neat piece of work by @Jnogales_SBG and his team. #SEVA plasmids put to great use! 🔗 academic.oup.com/nar/article/51…

🔧 Need a custom plasmid for your #SynBio research? With #SEVA’s modular system, you can quickly assemble the perfect vector by combining origins, markers, and cargo. Simplify your workflow today! 👉 seva-plasmids.com

We use bacteria to create real-time images! British artist Howard Boland from @clabblurb blurs the boundaries between art and science by using synthetic biology to create unique pieces of living art. 🎨 c-lab.co.uk/projects

AI-designed CRISPR enzymes? Using machine learning and high-throughput engineering, researchers at @harvardmed created custom-made Cas9 enzymes with tailored PAM profiles. This offers higher precision and fewer off-target effects than existing tools. 🔗nature.com/articles/s4158…

🧬 Unlock the potential of synthetic biology with #SEVA plasmids! Our platform provides a vast range of standardised, easy-to-use vectors for all your experimental needs. Get started now: 👉 seva-plasmids.com

Researchers at @Tsinghua_Uni used #SEVAplasmids to implement a lactose-inducible T7-like system in Halomonas bluephagenesis. This system achieves higher yield than IPTG-based systems reducing cost and toxicity 👉sciencedirect.com/science/articl…

Using modular, high-copy pSEVA351 #plasmids, researchers @ufz_de improved enzyme activity under oxygenic conditions in Synechocystis. They were able to precisely control hydrogenase and maturation gene expression in Synechocystis⚙️ Read more 👉 link.springer.com/article/10.118…

👩‍🔬💻 Struggling with incompatible plasmids? #SEVA’s universal vector system guarantees compatibility across a variety of bacteria and yeasts, boosting reproducibility in your #SynBio experiments. Discover more: 👉 seva-plasmids.com