Hugo Tejeda
@NeuroTejeda
Neuroscientist. Views are my own.
Happy to share the latest preprint from the lab. Work examining the role of somatostatin neuropeptide transmission in the PFC in regulating associative learning underlying discrimination between salient and neutral outcomes. Led by @Miigii13 biorxiv.org/content/10.110…
Unpacking the dynamic role of physical effort in shaping behavior Opinion by Boris Cheval (@chevalboris), Silvio Maltagliati (@Maltagliati_s), Florent Desplanques (@Flodsplqs), & Wanja Wolff (@WolffWanja) tinyurl.com/3rwkr9rx
🧠 🍄 ⚡️🐭 Now published in @NatureNeuro … Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility nature.com/articles/s4159…
Excited to present my first first-author preprint from the Corder lab, with @EAHellerPhD and @flybottleescape – Psilocybin-enhanced fear extinction linked to bidirectional modulation of cortical ensembles. biorxiv.org/content/10.110… 1/10
This speaks to the importance of cross-species research that is constantly forward & back-translated between the clinic & lab. The importance of animal models leading to unanticipated discoveries - even in the realm of human psychology - is invaluable, especially in #psychiatry🧠
New paper!🚨📝 Paper: tinyurl.com/2cycsy6d Press release: tinyurl.com/yur3j2n8 How the 🧠 engages in change-of-mind decisions taps into cognitive biases that depend on sensitivity to sunk costs & regret - both of which may contribute to negative rumination…however🧵👇1/6
GREAT NEWS! Our paper on dopamine signaling of valueless prediction errors is out in @ScienceAdvances! I found that striatal dopamine tracks cue-cue prediction errors in sensory preconditioning, which goes against model-free theories of dopamine function. science.org/doi/10.1126/sc…
:Trends in Cognitive Sciences The interoceptive origin of reinforcement learning cell.com/trends/cogniti…
Our new paper in collaboration with Bill Carlezon and @ErikMusiek on the effects of pain on sleep architecture is now out at @npp_journal . Work done by the amazing @DominikaJBurek and @khairunisa_ibk nature.com/articles/s4138…
A new study in mice uncovers a stress-sensing circuit that interacts with light to influence circadian outputs. The work offers a roadmap for exploring the circuits linking light, circadian/sleep, and stress-related psychiatric disorders. scim.ag/4kV9GcA
Our Lab @NIH sponsored work is out! cell.com/cell-reports/f… 🥳Vasopressin (AVP) excites BNST neurons via oxytocin receptor (not V1aR or V1bR) 🔬AVP excites CRF- and OTR-BNST neurons 🧠AVP inputs from SCN & SON excite BNST via OTR 🐁OTR-BNST neurons reduce anxiety in male rats
I am so proud of my partner @Dr_Paulevj for being such an inspirational force for good and science. Congrats on your tenure!
Today, I was awarded tenure at the National Institutes of Health (NIH)—the equivalent of becoming a tenured full professor at a major research university. I’m deeply grateful To God To my family To my mentors To every mentee #NIHTenure #ScienceIsService #Gratitude #WomenInSTEM
Thrilled to see this come to life and to have been part of the journey since the very beginning. Huge congratulations to Pablo and Gilles on building such a nice story! nature.com/articles/s4159…
Dendritic inhibition terminates plateau potentials in CA1 pyramidal neurons First preprint from the lab! Wonderful team effort, lead by incredibly talented Lee Vaasjo (@LVaasjo) and Shawn Kotermanski biorxiv.org/content/10.110…
Nature Reviews Neuroscience Brain mechanisms underlying the inhibitory control of thought nature.com/articles/s4158…
Our paper on opioid receptor regulation of mPFC inhibitory microcircuits is out as an early release jneurosci.org/content/early/… @allichonmc @mejoffe ! More to come on these systems in opioid dependence 🧠
Almost all neurons co-release peptides and small transmitters. Thrilled to share our latest research where new GRAB sensor promotes better understanding of the dynamics and molecular regulation between neuropeptide and neurotransmitter release in vivo. nature.com/articles/s4146…
Dr Paule V. Joseph @Dr_Paulevj, NIAAA & NIDCD Intramural Researcher, was selected to be part of the @PLSprogram, which brings together a diverse network of established leaders to collaborate & make a difference in the world. presidentialleadershipscholars.org/2025-class-of-…
I’m excited to share the most recent study from the @mbruchas lab, which represents the culmination of my postdoctoral work, and serves as the platform for my future research programs investigating the in vivo role of the endocannabinoid signaling system! biorxiv.org/content/10.110…
This sounds pretty cool!
Registration for the 2025 @MPFNeuro Neurotechniques Course closes this Wednesday! Co-directed by @Ryohei_Neuro & @denisejcai and led by an amazing team of experts, this hands-on course is a great opportunity to learn cutting-edge methods in neuroscience 🔬🧠