Becca Cole
@Beccaaa_57
Neuroscience PhD student in the Joffe lab @ the University of Pittsburgh | interneurons, opioids, and PFC | Boston U ‘22 | she/her
Our paper on opioid receptor regulation of mPFC inhibitory microcircuits is out as an early release jneurosci.org/content/early/… @allichonmc @mejoffe ! More to come on these systems in opioid dependence 🧠
Happy to share the latest preprint from the lab. Work examining the role of somatostatin neuropeptide transmission in the PFC in regulating associative learning underlying discrimination between salient and neutral outcomes. Led by @Miigii13 biorxiv.org/content/10.110…
Incredibly grateful for my @NIDAnews F31 to study DOR signaling in oxycodone dependence and withdrawal
NGA for @Beccaaa_57 F31 arrived today! Very glad to see her work and potential recognized with support from @NIDAnews
So honored to have been 1 of the 50 recipients of this grant, which was instrumental in launching my career! In uncertain times, it’s reassuring to see Hello Bio stay committed to investing in and supporting the future. Grateful to be featured in this article—give it a read ⬇️
We’ve reached a significant milestone in our support for life scientists! 🎉 We've just selected the 50th winner of our Early Career Scientist Grant & caught up with some previous winners to find out how it helped: ow.ly/4iCh50Vjc5a #sciencefunding #earlycareerscientists
Excited to present some of @Beccaaa_57's work on opioid receptor regulation of PFC transmission today! Very thorough characterization and some neat findings in a model of opioid dependence. Come find me at M217. @ACNPorg #ACNP2024
made it out of the lab to see @KamalaHarris !!! 👑 💙 #pittsburghforharris
DOR’s biggest fan
Congrats to @Beccaaa_57 for earning an amazing score on her F31!! So proud of the work she’s put into this project and excited to see where it will go
Our lab is hiring at all levels. Currently have postings up for entry level, more senior, and postdoc positions. Please reach out if interested! careers.upmc.com/job/21068977/r… careers.upmc.com/job/21069047/r… cfopitt.taleo.net/careersection/…
Honored to have been selected as a finalist for the Stephen L. Phillips “Best Peer-Reviewed Publication” Award 🎉 Big thanks again to @mejoffe and @SeneyMarianne 😊and for @FarrisSP for coming to support! @NeuroatPitt
Mu and Delta Opioid Receptors Modulate Inhibition within the Prefrontal Cortex through Dissociable Cellular and Molecular Mechanisms biorxiv.org/cgi/content/sh… #biorxiv_neursci
Presynaptic and somato-dendritic DOR functions are greatest in SST cells, while MOR's effects and putative subcellular location vary extensively across cell types. Lots of neat data in this one, including a new tool made by @FlyBottleEscape and @gsalimando to target MOR+ cells
Excited to share our first foray into opioid research! @Beccaaa_57 set out to build a comprehensive picture of opioid receptor function within PFC interneurons. Becca characterized several pronounced and contrasting effects across the major GABAergic cell types and circuits...
Mu and Delta Opioid Receptors Modulate Inhibition within the Prefrontal Cortex through Dissociable Cellular and Molecular Mechanisms biorxiv.org/cgi/content/sh… #biorxiv_neursci
so much fun + such cool science at my first Addiction GRS/GRC !!🦞🧠🥹
Honored to have received the official Notice of Award for my F31 NRSA application the other day! 🎉 Huge thanks to @NIAAAnews for supporting my work and all those who helped me through this process @mejoffe @mtorregrossa1 😊
Just received the NGA for our new @NIDAnews DP1! I am thrilled we will be able to investigate new targets in SST cells for the treatment of OUD. Major thanks to the support from @McClungColleen @MoussawiKhaled Larry Zweifel, and all who helped develop and refine this proposal!
Some photos from the inaugural Joffe lab scavenger hunt 2024
#ThisWeekInNPP New findings from @carlyfabian231 @mejoffe @SeneyMarianne @Beccaaa_57 @WinterThompson find that parvalbumin-expressing interneurons in the PFC are more excitable in ♀️ 🐭than ♂️🐭 with sex-specific regulation by mGlu1 & mGlu5 receptors nature.com/articles/s4138…