María Á. Núñez-Sánchez
@MANunezSanchez
Deep phenotyping of health–disease continuum in the Human Phenotype Project | Nature Medicine nature.com/articles/s4159…
Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids. @NatureComms nature.com/articles/s4146…
Bugged before birth? How maternal microbes reprogram offspring immunity Preview of @CellCellPress paper showing maternal antibiotic treatment induces dysbiosis & impairs offspring immunity to influenza. CD8 Tcell dysfunction reversed w/Bifido metabolite cell.com/cell-host-micr…
Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity. @Cell_Metabolism cell.com/cell-metabolis…
GLP-1 Therapy Helps Amplify Bariatric Surgery Weight Loss, But Timing Matters | MedPage Today medpagetoday.com/meetingcoverag…
⭐️Thrilled to share our latest publication! We found that GLP-1 receptor agonists, commonly used for diabetes and weight loss, are associated with the development of small intestinal bacterial overgrowth and intestinal methanogen overgrowth🦠 #GITwitter journals.sagepub.com/doi/10.1177/26…
Gut microbiome in metabolic dysfunction-associated steatotic liver disease and associated hepatocellular carcinoma @NatRevGastroHep nature.com/articles/s4157…
Intestinal pH: a major driver of human gut microbiota composition and metabolism @NatRevGastroHep nature.com/articles/s4157…
Spatial regulation of glucose and lipid metabolism by hepatic insulin signaling @Cell_Metabolism cell.com/cell-metabolis…
Dietary control of peripheral adipose storage capacity through membrane lipid remodelling. @NatMetabolism nature.com/articles/s4225…
Today in @Nature! Researchers led by Drs. @homamajd & @FaranakFattahi introduce a platform based on human #pluripotent stem cells for therapeutic development targeting GI motility disorders. 💡 Learn more: go.nature.com/3Ta1PeN
Happy to share our recent work on MASLD single cell eQTL! We conducted snRNA-seq of 50 tissues, called eQTLs and interacting eQTLs (ieQTLs). We also identified upstream regulators of some of the ieQTLs and validated its implication in MASLD. nature.com/articles/s4158…
🔬El IMIB, junto a FFIS, impulsa un programa que anima a los especialistas en Medicina Familiar y Comunitaria a realizar su tesis doctoral. Cada línea contará con un investigador de referencia del IMIB para guiar y apoyar el trabajo de los investigadores, laverdad.es/salud/imib-ffi…
Modeling diabetic intestinal organoids: Aspects of rapid gut barrier disruption sciencedirect.com/science/articl…
FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression @Cell_Metabolism sciencedirect.com/science/articl…
Amycretin, a novel, unimolecular GLP-1 and amylin receptor agonist administered subcutaneously: results from a phase 1b/2a randomised controlled study thelancet.com/journals/lance…
6 physiological hallmarks of aging and how we fight them. These six hallmarks decline predictably with age: •VO₂ max •Grip strength •Gait speed •Brain volume •Lean mass •Bone density But here’s the key: They’re all modifiable.
🏆 Ayer estuvimos presentes en los Premios Lycem reafirmando el compromiso de FFIS/IMIB con el talento joven, la excelencia académica y el impulso a la investigación en la Región de Murcia. 👏 Enhorabuena a todas las personas premiadas por su esfuerzo y dedicación.
Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions @ImmunityCP cell.com/immunity/fullt…
Endocrine-disrupting chemicals and female reproductive health: a growing concern | Nature Reviews Endocrinology nature.com/articles/s4157…