Organoid News

Dr. Ann Parr and team developed 3D-printed #organoid scaffolds for transplantation using clinically relevant hiPSC-derived regionally specific spinal neural progenitor cells. @umnneurosurgery 📖 Learn more about spinal organoids: bit.ly/44NljN2

Congrats to Dr. Megan Orzalli at @UMassChan on receiving a 2025 Investigators in the Pathogenesis of Infectious Disease award from @BWFUND! 🎉 Her lab is developing 3D skin-like tissues to mimic interactions between #HerpesSimplexVirus and its human host.…

There are only a few days left to submit your abstract for a chance to present your research to an international audience at Organoids Are Us 2025. 📆23 - 26 September 2025 📍Glasgow, Scotland Find out more about the invited speakers and program here: bit.ly/4lGeToY

This review summarizes recent protocols that have been developed to generate human microglial-containing cerebral #organoids, focusing on the methods used to assess the level of microglial maturation compared to their in vivo counterparts. 🧠 👉 bit.ly/4mbvL6z

In this new @cgtnature study, researchers found a link between APC mutation type, #organoid maturation, and FAP severity. They show that rapamycin rescues APC-mutated colon organoid differentiation. 🧫 More here: go.nature.com/4muH3TZ

🔉 Organoid researchers, check out this @embojournal article about kidney organoids! Scientists established a chemically defined, serum-free protocol for prolonged culture of human fetal kidney-derived organoids in vitro. 💡 Learn more: bit.ly/3II8jzK

Researchers led by Drs. Pranavkumar Shivakumar & Jorge Bezerra from @UTSWMedCenter show that modulation of TGF-β-dependent EMT regulates bile duct epithelial development. 🔓 More here: go.nature.com/4lCfVSF

👀 Dr. Brian Hafler's team at @YaleMed obtained viable short-interval postmortem human retinal tissue and generated human retinal organoids that contain electrophysiologically active neurons. @ScienceAdvances | bit.ly/4lDtUI6

🧫Dr. Sandra Petrus-Reurer's team at @CambridgeBRC used co-cultures and humanized mouse experimental models to examine autologous and allogeneic immune responses to human primary cholangiocyte organoids as treatment for bile duct disorders. @CellRepMed | bit.ly/3IxJtT0

Organoids Are Us is a symposium to report and discuss the latest advances in #organoids to tackle unanswered biological and clinical questions. 📆23-26 September 2025 📍Glasgow, Scotland Only two weeks left to submit your abstract. Register now! 👇 bit.ly/4nrFZRN

Working with organoids? 🧫 Stay up to date with the latest in 3D culture, disease modeling, and regenerative science via Organoid News by @STEMCELLTech Science News. Subscribe for free email newsletters: bit.ly/4kkWMEu

👂 Scientists developed a cochlear #organoid culture system using synthetic GelMA hydrogel, which promoted the spontaneous clustering and organization of cochlear stem cells, thereby accelerating organoid formation. @acsnano | bit.ly/44SUHZS

The induction of tissue-specific #vessels in in vitro living tissue systems remains challenging. Researchers in the @TakebeLab at @sciencetokyo_en have developed hPSC-derived #LiverBudOrganoids with self-organizing sinusoidal vessels. 🔬 Read the @natBME study:…

⌛ Tick tock, one week on the clock! Subscribe to one of our 20 immunology or cell biology newsletters before July 18 for a chance to win a personalized lab coat. bit.ly/3YYyzuM

Researchers led by Drs. Nicolas Dulphy and Valeria Bisio at @univ_paris_cite have developed a fully-human artificial #MarrowOrganoid model to study interactions taking place between mesenchymal stromal cells and HSPCs during hematopoietic differentiation. 🧫 Read the…

Researchers led by Dr. Senthil Muthuswamy (@3dorganoid) at the @NIH have developed patient-derived head and neck tumor #organoids that model tumor biology and chemoradiation responses. 🗒️ Read the @SciReports study: go.nature.com/4nWQwF9

Researchers led by Dr. @Sergiu_P_Pasca have developed a scalable cerebral cortical #organoid platform by screening biocompatible polymers that prevent the fusion of organoids cultured in suspension. 🧠 Read the @natBME study: go.nature.com/4eHTaKG

🤰 Maternal inhalation exposure to polypropylene nanoplastics during pregnancy disrupted fetal brain development and contributed to neurobehavioral disorders in offspring. Gain more insights: bit.ly/4eE8nfO

Scientists established cortical #organoids derived from Hutchinson-Gilford #progeria syndrome (HGPS) patient-iPSCs from patients with HGPS to investigate the role of progerin in the brain. 🧠 Discover the findings: bit.ly/3IaemwC

Read about jawbones in a dish in this new @Nature study. 🧫 Scientists from Kyoto University present a method for generating jawbone-like #organoids from #hiPSCs through PA1 ectomesenchyme of the mandibular prominence. go.nature.com/4ewsD2P