Andras Lakatos
@LakatosLab
Neurobiologist & Neurologist. My lab focuses on the biology of astrocytes/neurons & develops organoid disease models to study their role in neurodegeneration.
Stem Cell Models of Neurodegeneration International Symposium - scmnd.com/Speakers.html - a meeting to join!
New pre-print from our lab here: biorxiv.org/content/10.110…
The first @EMBO #Astrocyte #Meeting was a success. Thanks to our engaging lineup of excellent speakers, brilliant trainees & essential @DiBio_UniPD volunteers. Looking forward to the next iteration! @LauCiviero @theOlgaSin @wonsukchung Matthew.Holt
EMBO Astrocyte Workshop - this will be a 'stellar' meeting. Join us!
Origin and cell type specificity of mitochondrial DNA mutations in C9ORF72 ALS-FTLD human brain organoids | Science Advances science.org/doi/abs/10.112…
This is important: without urgent action clinical academia in the UK is at serious risk of dying out. ukri.org/news/report-ca…
It is truly unbelievable - how long can this go on?
With universities unable to afford them, clinical academics across the country are being offered redundancy. These are the people who teach our doctors and conduct ground breaking research. More must be done to support them.
ANOTHER exceptional 3D organoid models session at #SCMND2025? What a treat! Come join us in Edinburgh this March for some incredible science! Submit your abstract and register here 👉👉scmnd.com @UKDRI @bhuvaneish @LakatosLab @NeuralStemCells #iPSC #organoids
Interested in #oligodendrocyte metabolism and/or #multiplesclerosis? Our paper is now at Biorxiv! We show that oligos express MCT2, the high affinity monocarboxylate transporter, well known for supplying neurons with astrocyte-derived lactate (astro-neuron lactate shuttle)👇
Monocarboxylate transporter 2 is required for the maintenance of myelin and axonal integrity by oligodendrocytes biorxiv.org/cgi/content/sh… #biorxiv_neursci
Interesting paper on the role of KIF5A in axon biology - doi.org/10.1016/j.nbd.… - similar structural and mitochondrial transport findings to those we found in #astrocyte processes in KIF5A deficiency: doi.org/10.1038/s42003… in Communications Biology.
Full house at our Departmental Away Day - Clinical Neurosciences @Cambridge_Uni
A postdoctoral Research Associate position is available in the @LakatosLab in complex human neural organoid-based ALS disease modelling at @Cambridge_Uni : jobs.cam.ac.uk/job/49564/
Cambridge "Academic Tourists" from the @LakatosLab are having a great time at the Oxford Stem Cell Institute Meeting. Thanks to Colin Goding for the invite!
Discovery of Open Reading Frames in Zika viruses and their impact on neural cell tropism examined in brain organoids. A rewarding collaboration led by @NereaIrigoyen at @Cambridge_Uni.
Our latest research ‼️🚨🚨 ‘Zika viruses 🦠 encode 5’ upstream open reading frames affecting infection of human brain cells 🧠’ What does it mean? 👇🏾👇🏾👇🏾 nature.com/articles/s4146…