Maurizio De Pittà (@mdepitta.bsky.social)
@m_depitta
Quodlibetic twitter on #Neuroscience and related #Arts. Luscious #glia supporter, prone to irreverence, and curmudgeonly when it comes to religions
1/8 #NEW #PaperAlert: How amyloid-β (Aβ) and glutamate build up in #Alzheimer sets #therapeutic opportunities tinyurl.com/4zvk4tnd Study by #NGILab @KCNhub @KBI_UHN graduate @giuliobonif w/ @BCAMBilbao @AchucarroGlia @alzassociation @alzheimerssoc @AlzCanada @ELSneuroscience
Happy to share this work putting forth the first #computational model of #developing #embrionic cortical circuits. Phenomenal team coordination by @PhyloBrain. Full artcle: tinyurl.com/wnk38w8r Thanks to @KCNhub @KBI_UHN @BCAMBilbao @AchucarroGlia for their support.
A recent study published in @ScienceMagazine unravels how #evolution shaped the #neurogenesis of the neocortex and similar brain structures in amniotes. Read more about the breakthrough work from @m_depitta @KBI_UHN and his international team ➡️ uhnresearch.ca/news/unravelin… @KCNhub
The human brain synchronizes visual signals by adjusting axonal conduction speed in the retina—revealing a previously unknown mechanism for precise perceptual timing @Annalis43262927 @FelixFranke7 @IOB_ch nature.com/articles/s4159…
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & for myself, expanding my inpatient neuropsychiatry work to the service…
A recent study published in @ScienceMagazine unravels how #evolution shaped the #neurogenesis of the neocortex and similar brain structures in amniotes. Read more about the breakthrough work from @m_depitta @KBI_UHN and his international team ➡️ uhnresearch.ca/news/unravelin… @KCNhub
That #LLM will outperform #humans in #science discovery is #hallucination. LLMs may aid discovery, but producing #foundational scientific #discovery is #serendipitous, which #LLM will confuse with #noise. I see LLMs as more useful for #fact-checking tinyurl.com/bdsx2mxa
Registration is open for a 2-day course on #multiscale approaches to #model #astrocytes hosted by @DiBio_UniPD and curated by me and @LauCiviero supported by @EMBO Info: tinyurl.com/yx3m6acy
I am happy to be able to migrate to a @bluesky Please join me there: @mdepitta.bsky.social Twitter (the real thing is finally back).
Program and Registrations are finally available for the @EMBO #Workshop "#Astrocytes: From Molecules to Systems" at the @univiu in San Servolo Island in #Venice IT April 14--18 2025. Please #share #disseminate #retweet meetings.embo.org/event/25-astro…
Super excited to share the first piece of work from my PhD! If you’re a fan of astrocytes, chemogenetics, and electrophysiology come check it out! biorxiv.org/content/10.110…
Nice study showing cortical co-ripples during semantic processing
Garrett et al. use intracranial EEG to show that cortico-cortical co-ripples increase during reading and semantic decisions. nature.com/articles/s4156…
Looking forward to #CNS2024Natal! We are organizing a #Tutorial and a #Workshop on #NeuralNetworks (plus #glia) with a fantastic line of speakers! Join us! —Tutorial (July 19): tinyurl.com/35wzda58 —Workshop (July 23–24): tinyurl.com/498djd8r
🚀 The final countdown is on! Just ONE WEEK until #CNS2024Natal! 🌟 Are your posters polished and your talks tuned to perfection? 🖼️🎤 Don’t forget a thing! Get ready to immerse yourself in cutting-edge neuroscience and connect with brilliant minds. 🧠✨ See you next Saturday!
The #LivingCosts that #immigrant #foreign #scientists face in the #UK as well as #Canada are yet one of the big challenges to our passion for #research in the #Academia theguardian.com/education/arti…
@ZhenyangSun @KCNhub @KBI_UHN @UofT @uoftmedicine presents at @CAN_ACN his preliminary data on #astrocytes anatomy. More to come soon!
Why we need good mentors
Why sometimes you need a PI
Our paper on #NeuobiologyOfDisease introducing a new #framework for #diagnosis & possible new #personal #treatment of #Alzheimer is featured on @UHN_Research @KCNhub @KBI_UHN @KrembilF w/ @giuliobonif @AchucarroGlia @ElenaAlberdi8 sciencedirect.com/science/articl…
Researchers at @UHN's @KBI_UHN used mathematical models to uncover the complex interactions between amyloid-β protein and neuron hyperactivity, unveiling promising pathways for early diagnosis and intervention of #Alzheimers. > uhnresearch.ca/news/alzheimer…; doi.org/10.1016/j.nbd.…
This work shows that astroglial gap junctions strengthen hippocampal network activity by sustaining afterhyperpolarization via KCNQ channels: Cell Reports cell.com/cell-reports/f…. This astroglial regulation promotes in vivo delta-theta oscillatory physiological activity.