Luis de la Torre-Ubieta
@LTULab
We study human cortical development and neuropsychiatric disease. BSCRC member: https://stemcell.ucla.edu/member-directory/luis-de-la-torre-ubieta-phd
Thanks for helping us share this work more broadly. Very excited to see how this resource will facilitate better understanding of brain development and neuropsychiatric disorders.
Researchers @UCLA & @Penn led by @LTULab & @mikejg84 have uncovered over 200,000 new gene transcripts in the developing human brain. Their findings could enhance our understanding of brain maturation & genetic risks for neuropsychiatric disorders. ucla.in/3wDH97t
Re-upping this ad for a #postdocposition in our lab 🧠 🧬🔬 RT appreciated 🙏
We are recruiting a postdoc! Have expertise in RNA biology and want to apply it to neuro and neurodev disorders? Then apply 👇🏼 📌 $73,588 💰 📌 access to postdoc housing 🏠 📌 Support for internationals 🌍 📌 Awesome view 😅 🙏 RT labs.icahn.mssm.edu/derubeislab/wp…
New in @ScienceMagazine: Our paper mapping gene/isoform/splicing regulation at pop-scale during human #neurodevelopment. Major developmental shifts in #genetic reg., New colocalized risk genes at ~60% of #psych #GWAS loci. #PsychENCODE24 science.org/doi/10.1126/sc…
Very proud of this incredible team which led this innovative work to move us closer to understanding the impact of isoform diversity in the developing brain and neuropsychiatric disorders.
Its out today in @ScienceMagazine. science.org/doi/10.1126/sc… Special thanks to @connorjops for his prompt analytical support during the project, and @ckvuong for her meticulous review ensuring no oversights in the manuscript.
Our paper on splicing isoforms in developing human brain is finally out in @ScienceMagazine! So grateful to @LTULab and @mikejg84 for letting me be part of this amazing work. Congrats @ashokpatowary Pan Zhang @connorjops! science.org/doi/10.1126/sc…
I’m honored to join Fred Hutch as Professor and Program Head of Biostatistics, and as the Donald and Janet K. Guthrie Endowed Chair in Statistics. Excited to be part of a deeply collaborative and scientifically vibrant community with a rich legacy of impact.
Here is a press release by @UCLAHealth that nicely summarizes the key findings from our paper published today @CellCellPress. uclahealth.org/news/release/m…
1/ I am beyond thrilled to share our new paper in @CellCellPress! We explored the regulatory principles underlying pleiotropy in psychiatric disorders. cell.com/cell/abstract/…
📢 Our center is recruiting MULTIPLE new faculty working in stem cell research and regenerative medicine! Apply today to join UCLA's highly collaborative multi-disciplinary research environment: recruit.apo.ucla.edu/JPF09745
Interested in the role of gene-isoforms in cortical development? Come see our work at #SfN24 today. Poster A12 8-12p.
Come see our work studying mechs of cortical development and neurodevelopmental disorders at #SfN24. Pstr. 257.12 / A12, Oct 8, 11-12p Pstr. 317.24 / A22, Oct 8, 4-5p We have openings for scientists with expertise in genomics interested in neuroscience. Come meet me at SFN!
New from @GeschwindLab: As part of the PsychENCODE Consortium, we performed single nucleus RNA and ATAC sequencing on ASD and Control brain samples to identify cell type–specific changes and the cellular regulatory networks perturbed by genetic risk factors. (1/)
How do quantities of brain cells – the fundamental unit of life – differ in Alzheimer’s disease, schizophrenia and autism? Our work on cell-type proportion shifts using methylomics is just out in @ScienceAdvances #PsychENCODE @mikejg84 @DanielVo10 science.org/doi/10.1126/sc… 🧵
This week in Science, @ScienceAdvances, and @ScienceTM, the #PsychENCODE Consortium lay out findings based on examining human brains at the single-cell level. Learn more: scim.ag/73Y #DecodingTheBrain
Wonderful time and science yesterday at @UWWaismanCenter. Thanks for the opportunity to share our work!
Interested in postdoctoral training in fundamental neurobiology in an environment of a world-leading R&D unit, apply to have the best of both worlds! Please RT 1/5
We are delighted to share our latest publication! It’s a useful resource to the organoid community, but also uncovers some interesting biology about how tissue shape influences cell fate. Check out the thread below from first author @ChiaradiaIlaria! dlvr.it/Sx38s6
I'm thrilled to share my first first author PhD paper investigating the link between brain organoid shape and tissue fate 🧵. Thanks to a wonderful teammate (Ivan Imaz Rosshandler) and great collaborators! A big shout out to @mad_lancaster 🧠🤩 authors.elsevier.com/sd/article/S19…