Kepler Mears
@KeplerMears
I much prefer the sharpest of criticism of a single intelligent man to the thoughtless approval of the masses - Johannes Kepler
Another banger
How do plasmids kickstart gene expression in new hosts? Our new review in Plasmid: “Strategies for zygotic gene expression during plasmid establishment” with Nathan Fraikin (@tacc_c lab). Part of the #ISPB2024 special issue (Hamamatsu, Japan)🧵1/6 doi.org/10.1016/j.plas…
How do plasmids kickstart gene expression in new hosts? Our new review in Plasmid: “Strategies for zygotic gene expression during plasmid establishment” with Nathan Fraikin (@tacc_c lab). Part of the #ISPB2024 special issue (Hamamatsu, Japan)🧵1/6 doi.org/10.1016/j.plas…
Every second of Coldplay I’ve listened to has been against my will
I apparently deleted a important “TnpA” label from my poster so now my week is ruined but if you want to help search for more mistakes and you are at the Microbial Populations GRC come see me Wednesday
Last summer I was lucky to attend the Woods Hole Microbial Diversity course and the most important thing I got out of it was meeting Liana. Her genuine curiosity and meticulousness shine in this super fun story on introns (i.e. the coolest RNAs). Excited to see what you do next!
(1/7) Very excited to share my first PhD preprint on the interactions of two of my favorite mobile genetic elements: phages and group II introns! biorxiv.org/content/10.110…
Observing Shabbat by not engaging with the weird white knighters who think they’re fighting antisemitism by harassing Jewish professors. Shalom, y’all. Try to be good to each other
“I think that reason is a pretense. I think that this is an attack on Harvard as a symbol of academia in the United States.”
I went on WBUR today to talk about the grant terminations and the importance of basic medical research wbur.org/news/2025/05/1…
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
During my rotation I got to work on this project and I immediately knew I would be a fool to pass up an opportunity to work with @soumya_kannan12 and @altaetran. Super thankful to have met, and learned from, you guys!
Evolution-guided protein design of IscB for persistent epigenome editing in vivo go.nature.com/44XVBph
Reposting with an eye catching figure because forgot
Llamas, dolphins and measles? Oh my! So thankful this story is finally breaking containment from my time in the @MangusoLab. Using pieces from viruses and llamas we engineered selective cell specific viral like particles with reduced immunogenicity for in vivo gene delivery