Guido J. Falcone MD, ScD, MPH
@GuidoFalconeMD
Associate Professor, Academic Chief and Director of Clinical Research, Yale’s Division of Neurocritical Care. Opinions are my own.
@GuidoFalconeMD @san_murthy @DespinaKontos
"Improving the Robustness of Deep Learning Models in Predicting Hematoma Expansion from Admission Head CT" doi.org/10.3174/ajnr.A… @SamPayabvash @columbiaimaging
our work on Automatic Detection and Classification of Cerebral #Microbleeds on SWI series Using YOLO and 3D CNN @GuidoFalconeMD @san_murthy @columbiaimaging @YaleNeuroICU @WCMCNeurology joig.net/show-101-464-1…
🧠 IV Thrombolysis in CADASIL: Safe & Effective? Two retrospective cohort studies below👇 📌 STUDY 1 🏥 609 CADASIL patients (Taiwan, Japan, Korea), 204 with IS 📊 Median age of 60y, 5 microbleeds, NIHSS 5. Small subcortical infarcts 💉 12 (5%) received IVT, 4 with low dose…
📣 Your career fulfillment, your patients’ neurological health, and #BrainHealth for all is our mission. The #AANAdvocacy is how we are going to get there. Join us! 🙌 @AANmember #NeurologyProud #StrongerTogether @KellyMcConeDC @davidevanstx ✅
Looking to get involved in #AANadvocacy? Learn how from President @NataliaRostMD on the latest episode of the #Neurology Minute. 🎧 Listen now: hubs.la/Q03tbYM30 #NeuroTwitter
Thank you, @GreenJournal , for highlighting our study on ischemic stroke rates and outcomes after cardiac interventions in the US 🫀🧠 Grateful to the @YaleMed Neurology, NSGY, CT Surgery teams for their collaboration #Stroke #neurotwitter #TeamScience
This study identifies contemporary perioperative ischemic stroke rates and outcomes following cardiac interventions in the United States hubs.la/Q03tf2Jv0
Looking forward to connecting with patient advocates, nonprofit leaders, and research partners at tomorrow’s #NINDS75 #Nonprofit Forum. Together, we’re building stronger partnerships to advance neurological health and research. #ABrainCoProud 🔗 bit.ly/42qimAL
Thank you for highlighting our work!
Having an APOε4 allele may be risk factor for brain hemorrhage with apixiban, a commonly used blood thinner for atrial fibrillation jamanetwork.com/journals/jaman…
Genetic information can both inform pathophysiology and guide patient selection. Happy to share our new study on APOE e4 and risk of intracranial hemorrhage in AF patients anticoagulated with apixaban. Take a look! jamanetwork.com/journals/jaman… @NeurologyYale @YaleNeuroICU

Beyond excited to see our paper online! @JAMANeuro We show how genetics (APOE ε4) may help us manage the complex balance of bleeding and thrombotic risk in atrial fibrillation patients on apixaban. Huge thanks to @GuidoFalconeMD and @MrDisability for their mentorship.
APOE epsilon ε4 is a significant risk factor for intracranial hemorrhage in patients with atrial fibrillation on apixaban. ja.ma/442CjwX @sheth_kevin @MrDisability
APOE epsilon ε4 is a significant risk factor for intracranial hemorrhage in patients with atrial fibrillation on apixaban. ja.ma/442CjwX @sheth_kevin @MrDisability
APOE and Intracranial Hemorrhage in Atrial Fibrillation jamanetwork.com/journals/jaman…
Submit your session proposals for #ESOC2026, taking place 6–8 May 2026 in Maastricht. Support the selection of topics, chairs & speakers for the Scientific & Educational sessions and help shape the future of #stroke care & education! 🔗ow.ly/l7Tk50VZTxN #VoiceOfstroke
Authors, editors, reviewers, and other potential users should use CONSORT 2025 when writing and evaluating manuscripts of randomized trials to ensure that trial reports are clear and transparent. Learn more in this Special Communication. ja.ma/43ZDey9
A YSM study published in @NatureNeuro sheds new light on how the #myelin sheath around nerve axons is changed in #Alzheimers disease, suggesting possible future #treatments: medicine.yale.edu/news-article/t…
Had a great time presenting Neuroscience Grand Rounds here at @YaleMed, very rewarding to present to your everyday colleagues! @NeurologyYale

@san_murthy @brianmacgrory @gcfmd @Braindoc_MGH @DLBHATTMD @GuidoFalconeMD @MatoukCharles @JMoccoMD @sheth_kevin @VCI_EricSmith @WendyZiai @hoomankamel @SamPayabvash @YNHHealth @YaleMed @Duke_Neurology @DCRINews @UCDMedicine @ProfSteveDavis @teddyyhwu @GeoffreyDonnan
It was a real pleasure to collaborate with #JasperSenff, @Dr_SanjulaSingh and many others in this study evaluating associations between the Brain Care Score and risk of both CVD and cancer. Take good care of your brain! academic.oup.com/fampra/article…

Apixaban might be even safer than aspirin for #stroke prevention (pooled RR 0.67 [95% CI=0.43–1.08]). Apixaban seems to be just in the perfect sweet spot !ahajournals.org/doi/epub/10.11…
Thank you @JGrutzendler, #YaleADRC and @Yale_OAIC for the opportunity to present our work on genomic emulation of clinical trials and multiomic analyses focused on #WMH. Always great to showcase the ongoing work of @CyprienRivier and @SanticlocMD @NeurologyYale @YaleNeuroICU
