Luciano Sposato ๐ฆ๐ท๐จ๐ฆ
@SposatoL
Stroke Neurologist โข ๐๐ฒ๐ฎ๐ฑ Stroke Program @WesternU โข ๐ฆ๐ฒ๐ฐ๐๐ถ๐ผ๐ป ๐๐ฑ๐ถ๐๐ผ๐ฟ Neurocardiology @StrokeAHA_ASA โข ๐๐ต๐ฎ๐ถ๐ฟ @WorldStrokeOrg H&B TaskForce
What if I told you it is possible to increase 6โฃ times the detection of cardioaortic thrombi in stroke patients with a simple tweak to your current workflow? ๐คฏ๐คฏ๐คฏ We would only need to screen 1โฃ4โฃ patients to find 1โฃ thrombus! Curious? Read on! DAYLIGHT Trialโฆ
๐ง Great paper on BNP and timing of AFDAS diagnosis ๐Ref 1 ๐ 374 #stroke pt w/o known #Afib, but AFDAS detected on cardiac monitoring (BIOSIGNAL & GRAZ cohorts) ๐ Inhospital AFDAS (72%): ๐งช NT-proBNP at admission predicts in-hospital AFDAS โช๏ธCutoff: 505 pg/mL โ AUC 0.83โฆ
Nuestra Red y Centro de ACV @SubRedNorte tendrรก este mes en la tradicional reuniรณn mensual un gran colega y amigo como invitado. El Profesor @SposatoL Sposato nos hablarรก de #ACV y FOP! Un Equipo de ACV de Alta Calidad al servicio de Bogotรก y su #redpublica @sheilambrasilโฆ
๐ง PFO Closure in Ischemic Stroke & TIA Patients โฅ60y ๐ doi.org/10.1177/239698โฆ ๐ Single-center cohort, n=239 ๐ด 120 patients โฅ60y โฑ 3.1y mean follow-up ๐ฏ Recurrent stroke rates โช๏ธPFO closure (โฅ60y): 6.1% (3/49) โช๏ธNo closure (โฅ60y): 25.4% (18/71) ๐ aHR = 0.11 (95% CI:โฆ
๐ง IV Thrombolysis in CADASIL: Safe & Effective? Two retrospective cohort studies below๐ ๐ STUDY 1 ๐ฅ 609 CADASIL patients (Taiwan, Japan, Korea), 204 with IS ๐ Median age of 60y, 5 microbleeds, NIHSS 5. Small subcortical infarcts ๐ 12 (5%) received IVT, 4 with low doseโฆ
In case you missed it: ๐ SANCTUARY SITES โ Background. Infarction probability (Pi) maps highlight vulnerable brain regions post-stroke (basal ganglia), but they could also be used for identifying infarction-resistant areas. ๐ง Population. 154 patients with isolated orโฆ
Nice paper by @Dr_No_Charite @Jan_FriSch et al. from @BerlinStroke @ChariteBerlin โ Background. Troponin elevation is common post-stroke, but mechanisms remain unclear ๐ง Population. 508 ischemic stroke patients with serial hs-cTnT in 1st 48h โ 254 with acute myocardialโฆ
A clinical trial led by LHSCRI and Western Universityโs @SchulichMedDent has helped improve the detection of hidden blood clots. See how this could enhance stroke treatment: lhscri.ca/news/clinical-โฆ
A great honor to present CoVasc-ICH at the #ESOC2025, establishing the feasibility of testing colchicine in acute ICH. The efficacy and safety of colchicine will be formally tested in the upcoming CoVasc-ICH 2. @Ash_Shoamanesh @ESOstroke @PHRIresearch @MacDeptMed
Delighted to have presented the results from the CERES TANDEM study in plenary session @ESOstroke #ESOC2025 Thanks the Steering C & all collaborators @NguyenThanhMD @carlosmictusvh @fdianamd @Diana_A_Sousa @ArKatsanos @adnan_mujanovic @_AdnanSiddiqui @ZiniAndrea @ELeNaZapS