Umberto Pensato MD 🇮🇹 🇨🇦
@UPensato
Neurologist & Assistant Professor //@HUNIMED @UCalgary @UniBo //#Neurology #Stroke #Headache #CARTcells
🧠💥 This is your brain's venous highway. One blockage here and it's game over. Swipe through the lifelines keeping your brain alive. #NeuroAnatomy #BrainScan #MRV #MedTwitter #StrokeAwareness
🧵Canadian Outcome Scale for Minor Stroke (COSMOS) is a newly proposed 7-point scale that accounts for performance limitations and losses of a person's hobbies or passions and of their employment, educational, service, or caregiving pursuits, besides just ADLs.
#STROKE Special Report by Baron from 2025 David G. Sherman Lecture: how PET revealed hemodynamic TIAs, validated the penumbra, showed penumbra persistence, proved patient selection matters, and uncovered selective neuronal loss. #AHAJournals ahajrnls.org/4lPYMFt
#FlashbackFriday ⚫️⚪️Validation of the Black-&-White sign to predict intracerebral hematoma expansion in the multi-center PREDICT study cohort 👉The B&W sign: ⬆️predictive performance for predicting occurrence & severity of hematoma expansion journals.sagepub.com/doi/full/10.11… @UPensato
#FlashbackFriday ⚫️⚪️Validation of the Black-&-White sign to predict intracerebral hematoma expansion in the multi-center PREDICT study cohort 👉The B&W sign: ⬆️predictive performance for predicting occurrence & severity of hematoma expansion journals.sagepub.com/doi/full/10.11… @UPensato
We introduce the "#leakycore"--where the ischemic damage is so severe that reperfusion is not only useless but potentially harmful. Prolonged and severe hypoperfusion are keys. #stroke @IntJStroke @WorldStrokeOrg @johanna_ospel @mayank_G0 @AshuPJadhav journals.sagepub.com/doi/abs/10.117…
Time and Severe Hypoperfusion: 2 Threats for Hemorrhagic Transformation in Stroke @IntJStroke @SageJournals @UPensato @johanna_ospel @AshuPJadhav hemostasistoday.com/science/hemorr… #Health #Hematology #HemorrhagicTransformation #HemostasisToday #IJS #InternationalJournalOfStroke…
Just Accepted! 🧠Study finds hemorrhagic transformation was associated with: ⏲️Onset-to-imaging time 🩸Presence of severe hypoperfusion ❌No interaction found between time & severe hypoperfusion Read more below👇 journals.sagepub.com/doi/abs/10.117… @UPensato @johanna_ospel @AshuPJadhav
Just Accepted! 🧠Study finds hemorrhagic transformation was associated with: ⏲️Onset-to-imaging time 🩸Presence of severe hypoperfusion ❌No interaction found between time & severe hypoperfusion Read more below👇 journals.sagepub.com/doi/abs/10.117… @UPensato @johanna_ospel @AshuPJadhav
📣New paper by @UPensato on the #leaky core in acute #stroke🩸🧠 @DCNSNeuro ▶️Severe hypoperfusion and time affect risk of hemorrhage ▶️BUT: No multiplicative interaction between the two ▶️their effects on hemorrhage risk are additive, not synergistic. journals.sagepub.com/doi/abs/10.117…
🚨save the date🚨Join us for a mind-blowing #BIOSTROKE2026 meeting🤯 in the beautiful city of #Munich☀️ Plus which other meeting is held in a #castle 🏰😉? ▶️biostroke.de/biostroke
We are happy to endorse the 2nd BIOSTROKE Meeting – a key event in stroke and neurovascular care. ESMINT-endorsed events: esmint.eu/events #ESMINT #StrokeCare @Aggour @GuenegoAdrien @VladimirKZagreb @anna_kyselyova @Roland_K_Schwab @JanHendrikBuhk @MPeyT1 @jc__ray
Which is the best book to learn #neurology for a medical student? (Looking for a clear, comprehensive, reasonable size, updated book) @MicieliA_MD @interneurona @neurona_critica @drkeithsiau @draravindganesh @nishita_singh3 @fabnascimen @a_charidimou @caseyalbin
🧠 The Circle of Willis may be a foundational structure, but variations are the rule, not the exception. From hypoplasia to persistent fetal patterns, these anomalies shape collateral flow & stroke presentations Let’s dive into the ones you’ll encounter 👇 #NeuroXtorial
👀Check out this overview of recent advances in #stroke #surgery 🧠🔪 @StrokeAHA_ASA 💡 ahajournals.org/doi/10.1161/ST…
Estimating the clinical penumbra🌒 in acute #stroke. Check out this #ESCAPE-NA1 sub-analysis by @UPensato @StrokeJournal 👀🚨 #neurorad #neuroIR @MDStebnerAl @mayank_G0 @mihill68 @DCNSNeuro ⏩j-stroke.org/journal/view.p…
The Canadian Outcome Scale for Minor Stroke (COSMOS): a much-needed, novel 7-point scale to assess more Individualized outcomes in patients with minor stroke (mRS is not sufficient). @StrokeAHA_ASA Kudos to @mayank_G0 @draravindganesh Salome and team. ahajournals.org/doi/10.1161/ST…
"Extended" CT angiography that includes cardiac and aortic imaging was shown in this RCT of 465 acute AIS/TIA patients to increase the yield of detecting a cardiac or aortic thrombus from 1.7% to 8.8%. Why not? @TheLancetNeuro thelancet.com/journals/laneu…
News from the Swiss Stroke Registry by @mbgoeldlin: DWI-lesions in ICH are frequent, already on admission before any intervention; associationbwith CAA and SVD burden. Suitable surrogate outcome in trials?@StrokeBern @GreenJournal neurology.org/doi/10.1212/WN…
🚨 No drugs. No wires. No incisions. Just sound waves. For the first time, we’ve used focused ultrasound to completely liquefy stroke clots in under 2 minutes—without the need for thrombolytics or catheters. Our latest study on histotripsy marks a major step toward a…