⚡️GREG_CORDER⚡️
@FlyBottleEscape
Assistant Professor @Penn • Dept Psychiatry + Dept Neuroscience + Dept Anesthesiology | Pain • Placebo • Poppies • Psychedelics
🧠 🍄 ⚡️🐭 Now published in @NatureNeuro … Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility nature.com/articles/s4159…
Excited to present my first first-author preprint from the Corder lab, with @EAHellerPhD and @flybottleescape – Psilocybin-enhanced fear extinction linked to bidirectional modulation of cortical ensembles. biorxiv.org/content/10.110… 1/10
A new study pinpoints an emotion-to-motivation gateway that converts painful signals into negative feelings, offering a promising target for non-opioid pain relief. Learn more in this week’s issue of Science Advances: scim.ag/3UraFoY
New paper out in @PNASNews. Thalamic CGRP neurons form a spinothalamic pain pathway relaying pain signal to the amygdala & insular, but not sensory cortex to encode the affective dimension of pain. Huge congrats to first author @SJ_J_Kang_24 & coauthors. shorturl.at/kFQiD
Big chunk of this work was all @NIH supported via early career and training fellowships 🙏🏼 K99/R00 @NIDAnews F31 NRSA @NIH_NINDS
⚡️🧠A nociceptive amygdala-striatal pathway modulating affective-motivational pain Now published on the cover of @ScienceAdvances !!! Improved with projection-specific, pain-active intersectional chemogenetic pain behavior Check it out 👇 science.org/doi/10.1126/sc…
For years I have dreamt of a tool that could neutralize pathogens the moment they emerge. Today we unveil ApexOracle—an AI that, from a pathogen’s genome and phenotypic knowledge alone, predicts which antibiotics will work and invents new molecules for threats it has never seen.…
The Fakira Lab at the Cooper Medical School of Rowan University is seeking a highly motivated postdoctoral fellow to join our R01-funded research project focused on neuropeptide receptor function in the context of pain and addiction.
PRF was always my favorite site to keep up with the flood of amazing pain science… So so happy to see it back in original form!
Check it out! The new interactive website for pain researchers around the globe is live! Webinars, podcasts, interviews and the fan favorite: Papers of the Week! You'll also find lively discussions, jobs, meetings, funding opportunities and more! painresearchforum.org
Ohhh 😮 check out what @adaiasand designed/made … Combined GRIN miniscope + 3 site LFP + EEG/EMG 🧠⚡️💤 #pain #sleep
Ohhh 😮 check out what @adaiasand designed/made … Combined GRIN miniscope + 3 site LFP + EEG/EMG 🧠⚡️💤 #pain #sleep
Not studying animal models would halt basic neuroscience. We don’t have good AI models of animal brains to study and we can’t study human brains at single spike single neuron resolution. Studying the brain using fMRI is like studying the economy from a telescope on the moon.
The @NIH announcement of no “animal model only” grants is arguably a bigger deal than the pending 40% budget cut. The question is what it really means. e.g., mice + AI = “not pure animal model” grant etc. @NIHDirector_Jay @NIH @HHSGov please clarify. I’m getting Qs galore.
Just published.
New research from @jomoronc @ErikMusiek @khairunisa_ibk reveals how chronic pain disrupts sleep—mirroring what patients experience and paving the way for better treatments. Learn more: anesthesiology.wustl.edu/mouse-study-li…
Ohhh 😮 check out what @adaiasand designed/made … Combined GRIN miniscope + 3 site LFP + EEG/EMG 🧠⚡️💤 #pain #sleep
My addictive consumption of Polar/Lacroix etc is scientifically justified
Sparkling Water Consumption Mitigates Cognitive Fatigue during Prolonged Esports Play biorxiv.org/content/10.110… #biorxiv_neursci
Huge congrats to Dr. Lisa Wooldridge! She crushed her PhD defense on central amygdala circuits in opioid dependence Incredible science, relentless rigor, and a fearless approach to tough questions So proud to be part of your journey, Lisa! 🧠🔥🎓🍾
#NGG is proud to present our next Thesis Defense given by Lisa Woolridge of the Corder Lab @FlyBottleEscape! Please join us in person or virtually (DM us for the link) on 7/1. Best of luck, Lisa! #PhAlmostDone 🥳
Excited to share the first 2(!) preprints from the Kebschull Lab. The amazing @HyopilKim developed MAPseq2 & POINTseq and used them to map the dopaminergic cells of VTA and SNc. tl;dr MAPseq2=10x cheaper, 4x better; POINTseq=easy cell type specific barcoding; DA neurons=very cool
🤮 more garbage takes in grant reviews .. we got a 5 and ultimately ND bc we have papers on bioRxiv that were to support the 20+ references for ACC/PAG/BLA roles in pain
im also an alzheimer's researcher now too ... 😜 angry CD68+ microglia eating some X-34 dyed plaques
