Ozan M. Demir

Pressure-Derived Indices in Left Main Coronary Artery Disease @CircIntv ➡️ PW indices differ significantly between the LAD and LCx in isolated LMCA due to inherent differences in microvascular resistance and coronary flow. 🔗ahajournals.org/doi/10.1161/CI… @TheBHF @kingscardio

🔑 We recommend using adenosine, dobutamine & ACh for full MB phenotyping in the cath lab 🔑 bit.ly/3TnnY9y @JEscaned @VTaqMD @ColletCarlos @iamritu @VijayKunadian @wfearonmd @habib_samady @JanetWeiMD @samitshahmd @Michel_CorbanMD @rajivxgulati @DrMarthaGulati

Great work by the SERIAL Trial investigators 👏 First RCT of FFR vs iFR in Serial Disease 🎯 FFR & iFR systematically overestimate the result of PCI in serial and diffuse coronary disease jacc.org/doi/10.1016/j.… @BCIS_uk @mmamas1973 @ncurzen @aayshacader @DFCapodanno @drjohnm

Great work @mattlkw and the SERIAL Trial group! 1️⃣ pre-PCI #pullback is essential (can change treatment strategy and target lesion) 2️⃣ BUT we tend to overestimate the effect of PCI/underestimate impact of non-target disease by FFR or iFR 3️⃣ must check post-PCI FFR+pullback

A clear and concise lay summary by @TheBHF on the impact of the LMCA Physiology study👏 🔗Manuscript: ahajournals.org/doi/10.1161/CI… - @CircIntv @SVRaoMD 🔗Editorial: ahajournals.org/doi/10.1161/CI… - @wfearonmd 🔗BHF 📰: bhf.org.uk/what-we-do/new… @kingsmedicine @kingscardio @Kings_BHFCentre

In severe AS women with no CAD fare worse then men. Sex differences in CAD impact after AS treatment. A Report from the PARTNER trials @vumcvalve @PPibarot @hahn_rt @SammyElmariahMD @Maria_C_Alu @ClavelLabo @OKhaliqueMD #AHAJournals ahajrnls.org/447lgvc

Acetylcholine provocation testing. How does dosing affect the diagnostic performance in the detection of coronary spasm in ANOCA? @RajanRehan23 #Cardiotwitter #AHAJournals ahajrnls.org/44ALvKs

Great cases and presentations from the @MonteHeart team. @EdwinHoMD @AndreaScotti21 @leoneppmd @UlrichJordeMD @m_assafin @MontefioreNYC

This study showed that the SAPIEN 3 Ultra RESILIA (S3UR) valve offers significantly better performance for #TAVR in severe aortic stenosis compared to the SAPIEN 3 valve. The S3UR valve reduces paravalvular leakage (PVL) and patient-prosthesis mismatch (PPM), especially in…

How fast can you get your Aortic Stenosis patient thru the system.? Time matters in TAVI candidates with decompensated aortic stenosis #AHAJournals @MichaelMc_Kenna @ThomasTreibel @guyll @Echo_Imaging @bartstructural ahajrnls.org/3ZRLsXS

Our publication in EHJ: In ILUMIEN IV, >50% of lesions were mod/sev calcified. OCT-guided PCI in calcified lesions reduced 2-yr rate of TVF and serious MACE - one of the best uses for OCT guidance! Free access link: academic.oup.com/eurheartj/adva…

📰tctmd.com/news/pressure-… 🔗ahajournals.org/doi/full/10.11… ⁉️ Should diagnostic thresholds for FFR, iFR, CFR be specific to each vessel. @TCTMD @TCTMD_Caitlin @CircIntv @SVRaoMD @wfearonmd @mmamas1973 @GreggWStone @drjohnm @ncurzen @rallamee @ShrillaB @gbiondizoccai @JEscaned

Pressure-Based Physiological Testing Results Diverge Between LAD, LCx tctmd.com/news/pressure-… @DrOzanDemir @divaka_perera @TheBHF @kingscardio @TCTMD @TCTMD_Caitlin @CircIntv @wfearonmd

@TheBHF funds more than 50% of cardiovascular research in the UK, leading to major advances in the fight against heart and circulatory disease. I will be cycling approximately 100km #L2B2025 on 15th June to raise funds for this amazing charity. justgiving.com/team/cardiaccy…

Non-coaxial transcatheter aortic valve deployment relative to the native annulus is associated with impaired valve early safety and increased risk of bioprosthetic valve failure 1 year after TAVR. jacc.org/doi/10.1016/j.…

In another study published in #JACCINT, the timing of noncardiac surgery after #TAVR was not associated with increased perioperative risk, suggesting that surgical delays based solely on interval from TAVR may be unnecessary. jacc.org/doi/10.1016/j.… #vhdAS #cvSurg

🔥#EuroPCR 2025 Major Late-Breaking Trials results: Angiography versus physiology-guided PCI in patients undergoing TAVI FAITAVI is the first study comparing FFR-guided PCI with angiography-guided PCI in patients with intermediate CAD and severe symptomatic AS undergoing TAVI,…

📢 Just released at #EuroPCR: New analysis from the #PROTECTED and #BHFPROTECT-TAVI trials on the use of #Sentinel during #TAVI. 🔹 No significant reduction ⬇️ in periprocedural stroke when used routinely 🔹 However, per-protocol analysis shows a #significant benefit of Sentinel…

Incidence, evolution and impact of cardiac damage in asymptomatic patients with severe #vhdAS ❤️‍🩹 Interesting analysis of the EARLY TAVR trial by @PhilGenereuxMD #EuroPCR 2025 🇫🇷 Should we redefine the definition of severe #vhdAS?

Valve-in-valve TAVR is safe and effective for small aortic annuli. A report from a Japanese Nationwide Registry presented @PCRonline #EuroPCR and published simultaneously @OhnoTuri @EuroInterventio #AHAJournals #cardiotwitter ahajrnls.org/45lfFCd

Looking forward to presenting invasive LV & RV pressure-volume loop data comparing the impact of MR reduction Vs elimination in #TEER 💫 Should MR elimination always be the goal⁉️ Promises to be an interesting session chaired by 🌟 experts @JoaoLCavalcante A.Duncan #EuroPCR