Kevin Tharp
@Derpology
Ignorance driven researcher applying haute couture blockchain omics-seq-oscopy to understand cellular mechano-metabolic relationships in cancer and aging.
Got quotes for concrete demo... labor being 2-3x my "hourly wage" as a PhD/Professor... Since the NIH NCI funding level is now so low... seems like a better use of my weekend to demo concrete than write grant applications to cure cancer... Great job, America! #braindraineconomy
I left a successful academic career in STEM after publishing 200+ papers. I believed in science and truth but learned the system valued optics over integrity, conformity over courage. In academia, bureaucracy replaced discovery, egos replaced expertise, and silence replaced…
So... the Republicans are now voting to suppress the Epstein files... isn't that what they said they would release...? axios.com/2025/07/15/eps…
A stress-NRF2 response axis polarises tumor macrophages and undermines immunotherapy biorxiv.org/content/10.110… #biorxiv_immuno
Excited to share that I’ve officially received the NIH/NCI Early-Stage K99/R00 award! So grateful for my mentors (Dr. Marcela Maus and Dr. Matthew Paszek), colleagues, and friends who’ve supported me. A slightly delayed but unforgettable birthday gift! 🎉 #K99R00 #NIH #MGH
@NIHDirector_Jay @NIH this is all on you
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
Trump's EPA intends to reverse a ban on asbestos, a carcinogen that causes disease and death from exposure.
Is @HP the equivalent of @UHC for the assembled computer industry? We have a 12k workstation... down for 3 months... and their solution is to replace the mobo 5 times... I guess they avoid a proper warrenty replacement like UHC evades accountability for care... #profit?
YAP, a protein known to help #cancer cells survive treatment, behaves very differently in cell culture models depending on how they are grown in the lab, highlighting the importance of mimicking tumour architecture to guide better drug strategies. elifesciences.org/reviewed-prepr…
Today, the American Association for Cancer Research (AACR) called on Congress to reject the Administration's nearly 40% cut to the @NIH budget and allocate a bipartisan funding increase to $51.3 billion for the agency to accelerate progress for patients. brnw.ch/21wSrQk
excited to share our latest work now online @NatMetabolism, led by @kyle_flickinger, where we unravel a mechanistic basis for the conditional essentiality of NADK, one of the many interesting hits from our previously reported CRISPR screening with HPLM rdcu.be/ekpu6
Mark my words... The ultimate luxury of modern'merica is retirement. Be rich or die on the job... that's the system... you're useless once you arent a cog in some billionaire's money machine. #eattheirbrioche "Qu'ils mangent de la brioche"...
New @ScienceMagazine Exposomics. We're not doing nearly enough to understand and mitigate our toxic environmental exposures. A very insightful perspective science.org/doi/10.1126/sc…
RIP CD47 $ALXO 😲Missed primary endpoint 😲😲Historical controls (yikes) 😲😲😲No disclosed ORR or stats (double yikes) -9% down to at $28M MC!?!?!?!?!? After >$600M invested..... globenewswire.com/news-release/2…
Thrilled to share our new @NatureCellBio paper, led by our amazing student @DohunKim96: Mitochondrial NADPH powers mitochondrial fatty acid synthesis to sustain lipoylation, mitochondrial translation, and oxidative metabolism. rdcu.be/eiyH7