Damian Young
@DamianYoung29
One part father, one part chemist, one part foodie, one part dog owner, one part history buff, one part coffee connoisseur, and now I’m out of parts.
Our work deorphanizing the nuclear receptor TLX which controls adult neurogenesis was published in PNAS. We are now generating TLX agonists that boost neurogenesis for treating neurodegenerative diseases such as depression and Alzheimer’s.#neurogenesis doi.org/10.1073/pnas.2…
I'm inspired to be awarded a $4.2M grant from the Bill & Melinda Gates Foundation for developing chemical probes that will help bridge the gap to safe, effective, affordable and nonhormonal contraceptives for women. It is time to get to work!
Our opinion piece is out today, "The origin of novel traits in cancer"! Do the phenotypes come first and only later are they locked in by genetic or epigenetic changes? Insights from evolutionary biology are super useful for understanding cancer! cell.com/trends/cancer/… #S_Frank
I am extremely grateful to be awarded a $5,000,000 Catalyst Grant from the Welch Foundation. This grant will be focused on further developing the science of DNA-Encoded Libraries (DELs) for generating small molecule ligands toward a broad spectrum of disease-related targets.…
I am honored to begin my role as Director of the Center for Drug Discovery at Baylor College of Medicine. Exciting times ahead. #DrugDiscovery #dels
Pleased to share our interesting story aimed at modulating MYC using PROTACS. MYC is cancer’s most notorious transcription factor, and our work demonstrates how elusive it can be. This paper also highlights how bifunctional PROTACS can promote some truly unanticipated outcomes.…
My daughter Sophia is officially a freshman at Harvard. An amazing journey begins.
I'm thrilled to announce that I will be chairing the 2026 Bioorganic Gordon Research Conference. Looking forward to assembling a fantastic group of scientists for this premier meeting. #grc #gordonconference #bioorganic
Novartis Associate Professor Robert Gilliard (@RJGilliard) embraces an expansive style of research, mixing different approaches and drawing from a variety of areas of expertise, including organic and inorganic chemistry. chemistry.mit.edu/chemistry-news…
Is there an extended cut to this interview? I could listen to @SchreiberStuart all day long.
During #DrugDiscoveryDay @RLCscienceboss had an in-depth discussion with @arenabioworks co-founder @SchreiberStuart around small molecule drug discovery, AI in chemical biology, & new models of funding science. Watch this conversation & more On Demand: bit.ly/44503Ak
From basic research to budding biotechs, under one roof with Stuart Schreiber bit.ly/3Tj5yaK @SchreiberStuart discusses his plans to tackle inefficiencies in the translation of biomedical research, through the newly launched for-profit institute Arena BioWorks
I wrote down my rules on how to Science. I hope you find it useful!
Today we celebrate @RJGilliard, Novartis Associate Professor of Chemistry @ChemistryMIT! He is a synthetic chemist whose research whose lab has developed synthetic methods to access molecules relevant to energy and environmental related problems. #BHM #BlackInChem #BlackandSTEM
Taking "induction of proximity" to a new level, Arena BioWorks, a Biomedical Research Institute that just launched in Boston, is bringing academic inquiry and biotech creation under one roof. prnewswire.com/news-releases/…
Just when you think JQ1 is out, it gets pulled back in… and with a longer half-life! Introducing JQ1-D. pubs.acs.org/doi/10.1021/ac…
The 11th International Symposium on DELs really "DEL-ivered". Great event put on by Jörg Schuermann and Dario Nero at ETH. There is some highly innovative science being conducted in the DEL space that will undoubtedly lead to valuable probes and drugs in the future.
The rise of degrader drugs, a review by Mingxing Teng at @bcmhouston and Nathanael S. Gray at @Stanford_ChEMH dlvr.it/Str3Yn
Check out our latest paper describing non-covalent and non-peptidic Mpro inhibitors derived from DEL screening! nature.com/articles/s4200…
