Daniel Portik
@DPortik
Bioinformatics scientist @PacBio. I work on metagenomics, methylation, and assembly, but also enjoy phylogenomics and frog/lizard evolution. 🦠 🐸 🦎 🧬
It's official, @PacBio has launched a new benchtop sequencer! Quick summary of the new Vega system: - instrument = $169k - consumables = $1100 per run - output = 60 Gbp, 24 hr run time This is the #HiFi sequencer #microbiology labs have been asking for. pacb.com/press_releases…
Another very insightful paper on #methylation and long-read sequencing by @gangfang_1, describing some important but frequently overlooked caveats. Gang provides a fantastic summary in his post, but here's my take too😅:
Preprint alert 🚨 Cautions in the use of @nanopore sequencing to map DNA modifications: officially reported “accuracy” ≠ reliable mapping in real applications. We performed a critical assessment of nanopore sequencing (across different versions of models) for the detection of…
New metagenome assembler for @Nanopore R10 and @PacBio HiFi reads from Jim Shaw
Announcing myloasm, a new long-read (ONT R10/PacBio) metagenome assembler. With @lh3lh3. myloasm-docs.github.io
Great keynote talk at #SFAF by Rob Knight, summarizing key innovations in #microbiome research over the past decade. One recent highlight is how long reads have transformed #metagenome assembly, particularly @PacBio HiFi reads. The future is complete MAGs!

Do you think long-read #metagenomics with #PacBio #HiFi is gaining momentum? I noticed there were more publications & pre-prints on this topic in 2024 (56) than 2022 + 2023 combined (54). Definitely encouraging! Full pub list: github.com/PacificBioscie…

A bright new day is here! 🦋 Follow us on Bluesky (bsky.app/profile/pacbio…) and stay connected for updates, innovations, and everything genomics. #PacBio
If #ASHG attendees can count on one thing lately, it’s @PacBio creating a buzz (and throwing a great party). This year was no exception! When PacBio launched their latest instrument, Vega, on Wednesday night, @OneRepublic was on site to help them do it. hubs.li/Q02Xhqyc0
Benchtop HiFi: PacBio Unveils Vega 🧬🖥️ omicsomics.blogspot.com/2024/11/bencht…
Today, we announced the first #PacBio benchtop long-read sequencing system, Vega. #Vega delivers all the functionality of #Revio into a compact, lower- throughput benchtop platform. bit.ly/3O0mP5b #ASHG24 #ASHG2024
Revio Refresh - my latest conversation with @PacBio CEO Christian Henry omicsomics.blogspot.com/2024/11/revio-…
It's beautiful weather today at the #cshlmbiome conference! @PacBio just hosted a packed microbial workshop featuring guest speaker @gangfang_1. He talked about studying the stable and dynamic nature of bacterial epigenomes, with an emphasis on HiFi #methylation data.

