Clive G. Brown
@The__Taybor
Disruptive Technologist. Recently brought nanopore sequencing from concept to market.
I spend a lot of time pondering how you’d practically and economically measure every bio molecule, certainly polymers like DNA/RNA/Proteins, in a drop of blood, in every person on the planet, once a week.
ModiDeC enables accurate detection of RNA modifications from nanopore data, helping scientists uncover how RNA shapes gene activity and disease. - @UnimedizinMainz rna-seqblog.com/modidec-a-mult…
Just in time …
Aging will be reversible in humans within 8 years
🚨Our fears appear to have been vindicated on the very first day of the Online Safety Act's enactment. Some footage of protests taking place this evening against illegal immigration is unavailable on X for at least some UK users, with a warning about a restriction due to ‘local…
I’ve been a long time circos plot denier.
If you want to make sure that nobody understands your results, draw them as a Circos plots. Their inventor is permanently residing in the 7th circle of visualization hell. 😆
3.5 million people currently live with cancer. Current cancer characterisation is slow, expensive & limited in its ability to deliver actionable insights in real-time. Watch how Oxford Nanopore sequencing has the potential for this narrative to be changed. nanoporetech.com/applications/r…
Long-read sequencing of 1,019 humans to construct an intermediate-coverage resource covering 26 populations from the 1000 Genomes Project #nanopore
*New Open-Access Long Read Resource*. We sequenced 1,019 genomes from the 1000 Genomes Project sample cohort using @nanopore. Sequencing data is available at bit.ly/4m8dlE2. @embl @HHU_de @IMPvienna @CRGenomica nature.com/articles/s4158… [1/8]
🚨: A 9,000-year-old skeleton in Somerset was genetically matched to a local man named Adrian Targett. Their mitochondrial DNA reveals an unbroken maternal lineage spanning 300 generations — the longest verified lineage in history.
"The world has never seen a government more radically libertarian than @JMilei's. But the amazing thing is not that it is working economically—Adam Smith would say, 'I told you so.' The true miracle is that Milei’s shock therapy is working politically."
What if targeted sequencing actually meant targeted? Uncover how Oxford Nanopore’s adaptive sequencing delivers high coverage, faster results & a more efficient workflow than WGS — all in our latest Nanopore Know-How post. Read here: nanoporetech.com/blog/adaptive-…
Leave health tests to medical professionals, researchers warn. thetimes.co.uk/article/c20797…
TechBros only want one thing and it’s NVIDIA DGX Spark launching in 3 days btw
A perfect coding model for MLX on Apple silicon.. Qwen delivered again. Runs quite fast on an M3 Ultra. Running the 4-bit quantized with mlx-lm:
>>> Qwen3-Coder is here! ✅ We’re releasing Qwen3-Coder-480B-A35B-Instruct, our most powerful open agentic code model to date. This 480B-parameter Mixture-of-Experts model (35B active) natively supports 256K context and scales to 1M context with extrapolation. It achieves…
But of course the price of gold will also fall. telegraph.co.uk/business/2025/…
The extended mobility of plasmids "conjugative transfer and plasmid-encoded advantages can sustain plasmid prevalence despite the plasmid paradox. Microbiome engineering is shifting to precision interventions at the strain, plasmid, or gene level." academic.oup.com/nar/article/53…
Jensen Huang: digital biology will be “one of the biggest revolutions ever” “Where do I think the next amazing revolution is gong to come? And this is going to be flat out one of the biggest ones ever. There’s no question that digital biology is going to be it.” Jensen…
Encounters with humanities academics often leave me with the impression that entire fields are built entirely on sand. It’s all clever wordplay and tedious commentary designed to cover up the fact the foundational assumptions are not correct.
Javier Milei fired 50,000 government employees, cut the government by 30%, & reduced the government ministries from 18 to 8. All while lifting 2.4 million children out of poverty, killing inflation, & providing a fiscal surplus every month of 2025.