Daniel Siegwart
@DJSiegwart
Siegwart Research Group | Department of Biochemistry | Simmons Cancer Center | Prof. Daniel J. Siegwart | UT Southwestern Medical Center | Posts are my own.
Congratulations to #UTSW Professor @DJSiegwart, Ph.D., for being named a fellow of the @AcadofInventors! Discover how his groundbreaking work in developing nanoparticles is revolutionizing treatments for various diseases. bit.ly/3Vwi0EX #futureofmedicine #utswmed
Rescued by fat bubbles: UTSW scientists treat rare genetic disease with designer molecule dallasnews.com/news/2025/07/1…
Last evening, we were proud to induct the newest class of NAI Fellows into the Academy. The highest professional distinction awarded solely to inventors, this distinction recognizes a lifetime of innovation, impact, and leadership in invention. These scholars have not only…
It was an honor to be inducted into the National Academy of Inventors (NAI) @AcadofInventors tonight!


Minigolf Monday Recap! We had a really great time at minigolf with the whole lab crew this Monday! ⛳️🙌 #LabLife
Congratulations to Dr. Minjeong Kim and all additional coauthors!
Our lab’s latest publication in @NatureBiotech led by Minjeong Kim and @DJSiegwart. Read the full story here: nature.com/articles/s4158…
Our lab’s latest publication in @NatureBiotech led by Minjeong Kim and @DJSiegwart. Read the full story here: nature.com/articles/s4158…
Amogh Vaidya, Graduate Student Researcher in the @GDE_UTSW Lab, successfully defended his dissertation "Development of Organ-specific Lipid Nanoparticles for Delivery of Nucleic Acid Therapeutics" on Friday, May 30. Congratulations, Dr. Vaidya!
Science at #UTSW goes deep – down to the nucleic level. Research led by @DJSiegwart has unlocked synthetic lipid nanoparticles as delivery vehicles for genetic medicines. Explore more in the latest edition of #DiscoveryAtUTSW. bit.ly/43AO6Ej
RBL LLC Announces Launch of Sentinel BioTherapeutics at the 2025 ASCO Annual Meeting finance.yahoo.com/news/rbl-llc-a…
A must watch (and share) on the importance of science funding. Clear articulation of the massive return on investment back to society. @davidrliu @GDE_UTSW
I discuss the urgent crisis from the loss of federal support of science in the US and recent clinical gene editing breakthroughs with @WalterIsaacson & @amanpour on @AmanpourCoPBS, airing on @PBS tonight at 11 pm ET, and on @cnni earlier today. Pls share! youtube.com/watch?v=8YhJM6…
Throwing it back today to celebrate @YehuiSun, @GDEatUTSW Graduate Student Researcher, for earning a scholarship award to attend @KeystoneSymp's Precision Genome Engineering meeting in March. Yehui gave a talk on the lab's most recent publication in Science. #ThrowbackThursday
Principal Investigator Daniel Siegwart (@DJSiegwart) and researchers at @UTSWMedCenter report the chemical design, synthesis and optimization of high-density brush-shaped polymer lipids that reduce anti-PEG antibody binding to improve protein production consistency in repeated…
@C_Martins__ and @juan_avetrece just wrapped up a fantastic interview with @DJSiegwart for the upcoming @CRS_YSC & @DDTReMedia joint series. Insightful, inspiring — and just the beginning. Stay tuned for what’s coming! #NewBeginnings #YoungScientists @CRSScience
Check out our work on brush-shaped polymer lipid as a potential replacement for clinically used DMG-PEG lipid for future mRNA therapeutics in @NatureMaterials led by @YufenXiao @DJSiegwart ⬇️
Lipid NPs containing brush-shaped polymer lipids as a replacement for commonly used PEGylated lipids enable the repeated administration of mRNA therapeutics without loss of performance in protein replacement therapy and genome editing models. @GDE_UTSW nature.com/articles/s4156…
Thank you to #UTSW Professor @DJSiegwart, Ph.D., who delivered an outstanding first presentation for this year’s President’s Lecture Series! It was a brilliant discussion of “Innovation in Nanotechnology: From Vaccines to Novel Genetic Disease Treatment.”
Congratulations to Professor @DJSiegwart, Ph.D., for delivering an exciting and educational presentation at the President's Lecture Series last night! Dr. Siegwart presented his lab's research on nanotechnology and the development of novel genetic disease treatments.
Congratulations to @SamuelAchilefu for being named a member of NAR Class of 2025!
Congratulations to our Chair @SamuelAchilefu, Ph.D., on being named a member of the NAE Class of 2025! #NAE2025
We are excited to host Dr. Daniel Siegwart as our esteemed guest for STORIES. Join us to learn about the remarkable journey that has shaped Dr. @DJSiegwart's career in STEM. Please refer to the flyer for more details.
Had an amazing time at the Pegasus Park for the annual @DJSiegwart lab and family holiday party 🎄 Special shoutout to Kohki for crushing it at the lab trivia game 🏆🧠