GDEatUTSW
@GDE_UTSW
Siegwart Research Lab | Program in Genetic Drug Engineering @ UTSW | Student-run
Our lab member Yufen @YufenXiao gave a fantastic talk on her recent publication: "High-density brush-shaped polymer lipids reduce anti-PEG antibody binding for repeated mRNA therapeutic delivery." at the #CRS2025! Congrats! 🎉 #mRNA #LNP


Yehui Sun, PhD candidate in @GDE_UTSW Lab, was presented with the Ida M. Green Award on Friday, July 11 during a small reception. Congratulations to Yehui for her commitment to research excellence, the well-being of fellow students and community service!
🚨 Exciting news! Dan is giving a talk on the development of selective organ targeting (SORT) lipid nanoparticles (LNPs) for genome correction of disease-causing mutations. @DJSiegwart @CRSScience #CRS2025 #Nanomedicine #LNP #GenomeEditing


Big congratulations to Yehui Sun, a PhD candidate in Siegwart Lab, for receiving the 2025 Ida M. Green Award! Your dedication, leadership, and excellence truly inspire us all!


Congratulations to Raiyan Zaman, Ph.D., Lukas Farbiak, Ph.D., and Jing Liu, Ph.D., who were recognized at today's department meeting for their years of service! Thank you for your dedication and hard work to the UT System. 🥳 🎉
🚀 New publication from our lab! We found that pKa (6.2–7.4) and buffering capacity may be valuable in predicting in vivo hepatic delivery. #RNAtherapy #LNP Read more: pubs.acs.org/doi/10.1021/ac…
Rescued by fat bubbles: UTSW scientists treat rare genetic disease with designer molecule dallasnews.com/news/2025/07/1…
Our new 3-component ZAL LNPs simplify mRNA delivery and enable extra-hepatic delivery. Acetate-modified ZALs show enhanced biocompatibility and immune cell transfection—paving the way for next-gen mRNA therapies! 🧬✨ #LNP #mRNA #DrugDelivery Read more: pubs.acs.org/doi/10.1021/ac…
Imagine treating a genetic disease affecting the lungs and liver with a single treatment. UTSW scientists are working to make this a reality. Discover how their innovative gene-editing delivery system could one day transform treatment options. bit.ly/3G4oWEy #GeneTherapy
Daniel J. Siegwart on Development of selective organ targeting (SORT) lipid nanoparticles (LNPs) for genome correction of disease causing mutations #RNATx2025
It was an honor to be inducted into the National Academy of Inventors (NAI) @AcadofInventors tonight!
🎉 Big News! 🎉 Huge congratulations to Amogh Vaidya, Graduate Student Researcher in the @GDE_UTSW, who successfully defended his dissertation: "Development of Organ-specific Lipid Nanoparticles for Delivery of Nucleic Acid Therapeutics" Congrats, Dr. Vaidya! 🧑🎓🔬 #PhDLife


Advancing Multi-Organ Gene Editing We’re excited to announce that Dr. Minjeong Kim and the team have developed a revolutionary gene-editing system capable of targeting livers and lungs simultaneously. Check out our feature in @UTSWNews: utsouthwestern.edu/newsroom/artic…
Minigolf Monday Recap! We had a really great time at minigolf with the whole lab crew this Monday! ⛳️🙌 #LabLife

Welcome our new postdocs, Dr. Koki Kunitake and Dr. Xi Liu! 🎉 Excited to have you both on board! 🔬✨ #Welcome #Postdocs #Research


👏 Huge congratulations to @YehuiSun from the @GDE_UTSW Lab for winning a travel award at the 2025 Celebration of Women in Science and Medicine! Her innovative work on in vivo editing of lung stem cells is truly inspiring. 🚀🔬 #WomenInSTEM #GeneEditing #UTSWBME
Congratulations to @YehuiSun, Graduate Student in the @GDE_UTSW Lab, on winning a travel award for her poster "In Vivo Editing of Lung Stem Cells for Durable Gene Correction in Mice" presented at the 2025 Celebration of Women in Science and Medicine Poster Session!
Science at #UTSW goes deep – down to the nucleic level. Research led by @DJSiegwart has unlocked synthetic lipid nanoparticles as delivery vehicles for genetic medicines. Explore more in the latest edition of #DiscoveryAtUTSW. bit.ly/43AO6Ej
Chair @SamuelAchilefu, Ph.D., is featured in this Science in 60+. Learn about his invention, Medical Vision Goggles, which help surgeons eliminate all cancer cells after tumor removal. The goal is to make them available to surgeons worldwide. bit.ly/3F6qAFg #UTSWScience
Check out Medical Vision Goggles, which help surgeons eliminate all cancer cells after tumor removal. Inventor @SamuelAchilefu, Ph.D., Chair of @utswbme, discusses the goggles and his goal of making them available to surgeons worldwide. bit.ly/3F6qAFg #UTSWScience