Cornelia Schwayer

Ever wondered how a tiny Hydra blob figures out where its head goes? Turns out, it's not just chemistry — it's feeling the stretch! Check out 👉 Mechanochemical patterning localizes the organizer of a luminal epithelium science.org/doi/10.1126/sc… #Hydra #morphogenesis #biophysics

🎉 Excited to share our new work: “Adhesion-driven tissue rigidification triggers epithelial cell polarity”, now on @biorxivpreprint ! A huge thank you to @petridou_ni , Bernat, @CristinaPallCar , Adrián, and everyone involved! 🙌 🧵⤵️

Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: cell.com/cell/fulltext/…

How do embryos ensure precise tissue patterning? It’s all about timing cell divisions! Our new preprint reveals how cell proliferation syncs with signalling oscillations to regulate precision of somite formation and growth. Check the full story: biorxiv.org/content/10.110…

I am very excited to share our most recent work on how ‘Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration’ ☺️ Thanks a lot to @Silvia_Bar01 @d_brueckner @prisca @EdouardHannezo and all the co-authors!

Researchers from the @TheCleversLab developed a method to grow organoids using a bacterial protein: Invasin. The study, published today in @PNASNews, shows that Invasin offers a sustainable, affordable and animal-free alternative to current methods. hubrecht.eu/Invasin-protei…

Happy to share the latest work from @DrPreetiSahuPhD, with @ASanchezDanes on the biomechanics of cell fate choices during tumor initiation! We implement/test a 3D vertex model with proliferation and fate choices for multilayered tissues! 🧵below (1/n) bit.ly/3ZXxJzk

If you are attending #CellBio2024 and are interested in understanding how the process of crypt morphogenesis is coordinated both in vivo and in organoids then come to my talk Wed Dec 18th in the subgroup “Organoids as tools to study the function of tissue in Health and Disease”

Have you ever wondered how cell heterogeneity can regulate tissue patterning and how such patterns are maintained? Then come to my talk at the ASCB meeting #cellbio2024 this Sunday afternoon ☺️

New preprint from the lab! We studied how single cells migrate up, down and about fibronectin gradients. Experiments by @icfortunato , theory by David Bruckner. Collaboration with @EdouardHannezo and @RaimonSunyer @IBECBarcelona biorxiv.org/content/10.110…

Looking for a postdoc position in nuclear #mechanobiology, with a strong interest in microfluidics, device design, fluorescence microscopy, and image analysis? Check out our opening: bme.cornell.edu/bme/job-openin… If you are attending #BMES2024, we can meet there. Please RT.

Super happy to see this heroic effort by @DimitriFabreges and Bernat Corominas out! Via a quantitative atlas of the developmental trajectories of dozens of embryos, we can see how robust shapes and fates arise from highly stochastic cellular processes! science.org/doi/10.1126/sc… 1/n

New Preprint! How can cells polarize in the absence of a stimulus? We suggest a surprising biophysical mechanism, protein caging! We reveal how the complex mechanical interactions at the cell surface lead to symmetry breaking. biorxiv.org/content/10.110…

New insights from the Hiiragi group show that the variability in how and when cells divide during embryonic development isn't an obstacle. Contrary to what scientists traditionally believed, this variability promotes healthy development. @DimitriFabreges hubrecht.eu/variability-ce…

3-year funded post-doctoral position to study oocyte development using a combination of cutting-edge approaches in cell biology and biophysics. If you are interested and want to know more about the project, please send a CV and contact me.

@TheCrick 2025 PhD programme is live. My lab is recruiting. crick.ac.uk/careers-study/… -  International and Inclusive PhD programme - Many training and career development opportunities - Collaborative environment with state-of-the-art technology platforms Join us!

One Million Euro Funding for Carl-Philipp Heisenberg

Happy to share our News & Views about the two new papers from @eric_lubeck and @GaublommeL. Congrats 🎉 to the authors for these great achievements in Optical pooled CRISPR screening 🧪🧫 and thanks a lot to @priscaliberali, @KahnwaldMaurice and @KC_Oost! 🧑‍🔬👩‍🔬👨‍🔬

🚨 We are hiring 🚨 ⬇️ Funded postdoctoral position in the Lecuit lab at Institut Pasteur research.pasteur.fr/en/job/funded-… Contact us at [email protected]

2. We wanted to check if cingulin-nonmuscle myosin2 interaction has additional roles, besides controlling tight junction and apical membrane cortex mechanics. We found that the myosin-binding region of cingulin is required to rescue defective cyst morphogenesis in 3D!