Irene Miguel-Aliaga
@FlyGutLab
Eternally asking questions. Likes guts. Has guts, and a lab @TheCrick
Latest from the lab: The Sex of Organ Geometry – aka ORGAN ORIGAMI! Organs exist in male and female configurations. For some 3D insights into how and why see rdcu.be/dJnkI (spoiler: it’s mechanochemical)
"Our participant, superwoman and co-senior author @chrastil underwent 26 multimodal MRI scans and venipuncture beginning 3 weeks pre-conception through two years postpartum. The data are simply...beautiful."
5 years ago, on the heels of 28andMe, our team designed a new precision imaging experiment: scanning an individual’s brain throughout her entire pregnancy. We are excited to share that these findings are out today in @NatureNeuro! nature.com/articles/s4159…
Flies gone Freudian. Cool work from @crezaval and lab
Sex or survival—what’s more important? Excited to share our @Nature paper on how flies resolve this conflict. We found a dopamine-based filter that reduces threat perception, helping flies focus on courtship when close to mating. nature.com/articles/s4158…
The Cordero Lab has openings for two post-docs positions. Please contact me if you are interested in doing cross-species research on local and systemic intestinal biology.
Image analysis opportunity in our lab @TheCrick - deadline June 25 crick.ac.uk/careers-study/…
@CellCellPress @MariaMMihaylova preview: Reaching for more: How reproduction transforms the maternal intestine cell.com/cell/fulltext/… cell.com/cell/fulltext/… @FlyGutLab
Tomo's take on his recent work with us - Tomo now his own boss @sciencetokyo_en
Re-growing adult organs: mothers do it best Tomotsune Ameku from the @FlyGutLab @TheCrick tells the behind the paper story of their work looking into maternal intestinal growth in mice during reproduction: thenode.biologists.com/re-growing-adu…
Happy to share the preprint with our latest work on gut/vascular interactions in flies and mice! biorxiv.org/cgi/content/sh…
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: cell.com/cell/fulltext/…
Please see below two manuscripts currently under review with the most recent research from the lab. biorxiv.org/content/10.110… biorxiv.org/content/10.110…
Very cool story, please read! Well done @KyraCampbellLab !
Online now: The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells dlvr.it/TG6yF7
🚨 Deadline approaching 🚨 Don’t miss your chance to join colleagues @HHMIJanelia to discuss the latest in enteric nervous system research. 🏨 Hotel + meals + registration covered Apply by Oct. 22 @ janelia.news/ENS25 @HHMINews @FlyGutLab #entericnervoussystem…
📢 Applications are open! Join colleagues @HHMIJanelia to uncover the mysteries of enteric nervous system evolution, development and function across a variety of species. Learn more & apply by Oct. 22 @ janelia.news/ENS25 @HHMINews @FlyGutLab #entericnervoussystem
Our latest from @TheCrick … Sebastian Sorge led on this amazing new chemically defined (holidic) diet for fast larval growth & development in Drosophila. It’s called HoldFast, soon to be available to the community, in powdered form, from @VDRC_flies. biorxiv.org/content/10.110… 
How do enteric neurons control gut function, communicate with the body + interact with the microbiome? Join colleagues @HHMIJanelia in March to address these questions. 🏨 Hotel + meals + registration covered Apply by Oct. 22 @ janelia.news/ENS25 @HHMINews @FlyGutLab…
📢 Applications are open! Join colleagues @HHMIJanelia to uncover the mysteries of enteric nervous system evolution, development and function across a variety of species. Learn more & apply by Oct. 22 @ janelia.news/ENS25 @HHMINews @FlyGutLab #entericnervoussystem
Bruno C. Vellutini from the research group of @PavelTomancak @mpicbg wins the 14th Annual Nikon Small World in Motion Competition @NikonSmallWorld with his video of mitotic waves in the embryo of a fruit fly. Congratulations! mpi-cbg.de/news-outreach/…
👏👏👏congrats and well deserved François!
#TalentsCNRS🥈| François Leulier, chercheur et directeur de l'@IGFLyon, est récompensé par la médaille d’argent du @CNRS pour ses travaux sur les interactions entre le microbiote, le développement et la physiologie animale. ▶️ buff.ly/3ZbnUOb
Join us in London for the 3rd Crick/Beddington Developmental Biology Symposium on 10-11 Feb 2025! Fantastic speaker lineup covering a cross-disciplinary exploration of development and regeneration. Loads of selected short talk slots! tinyurl.com/36xt6td3 #beddingtonconf
New paper out @Nature - why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? sex chromosomes or hormones? Here we studied adaptation of human immune systems to gender-affirming…
Latest from Bruno Hudry and lab, featuring tools to visualise endogenous TraF expression and genetically interrogate it nature.com/articles/s4146…
"Distinct but interconnected neural circuits process each step of food intake, from sensory detection of food to feeding initiation and sustained ingestion". Beautiful work!
My PhD paper is out! We imaged gut neuron activity in living, eating flies (first time in history!), and found a Gut-Brain-Gut neural circuit loop that allows fruit flies to adjust their ingestion bouts based on the sucrose concentration of the food! (1/n biorxiv.org/content/10.110…
I am pleased to inform you of the publication of the Drosophila immunity handbook. The pdf version of the book is free, or a physical version of the book is available for purchase at @EPFL press.epflpress.org/produit/1514/9…