Benjamin Kann, MD
@BenjaminKannMD
RadOnc @DanaFarber @BrighamWomens @HarvardMed via @Yale residency | machine learning, #AI, cancer imaging, outcomes, improving patient care | views=my own
How can we better predict if a child’s brain tumor will return—before symptoms start? In our new study @NEJM_AI, we used deep learning to analyze longitudinal brain MRIs—learning how scans change over time—to predict tumor recurrence in children. Let’s dive in. 🧠📊 👇 🧵1/

Are you driven to use AI to transform patient outcomes in oncology? My lab in the AI in Medicine Program (Mass General Brigham, Harvard Medical School) is seeking Postdoc Fellows to pioneer applications of AI—especially LLMs—in cancer care. More here: linkedin.com/posts/danielle…
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
Lean body mass–based oxaliplatin dosing reduces peripheral neuropathy in stage III colon cancer without compromising survival! ✅ Lower rates of grade ≥2 oxaliplatin-induced peripheral neuropathy ✅ Better quality of life ✅ No impact on relapse-free survival or overall survival…
Here it is! KEYNOTE-689 primary publication online now @NEJM. It’s been an incredible journey with DAdkins @SitemanCenter @WUSM. All started in early 2010s / now with @US_FDA approval and a new standard of care! @DanaFarberNews @BrighamWomens @BrighamSurgery
It was a real honor working with @anantm and @CJTsaiMDPhD on this companion piece to our ASCO education session. Exciting things ahead for AI applied to #HNSCC clinical care
Thrilled to share new @ASCO Educational Book Chapter! 📖🤖 AI for head & neck cancer—diagnosis to personalized treatment. 🔹 Better tumor diagnosis & prognosis 🔹 Multimodal AI for survival prediction 🔹 Early toxicity & complication detection Paper: tinyurl.com/4rd2c4kn
🧵1/ Big news in unresectable stage III NSCLC. The InTRist study is the first randomized trial comparing NAC vs. neoadjuvant chemoimmunotherapy (NAC-ICI) prior to definitive chemoradiotherapy (CRT). Early results are promising. Let’s dig in. 🔍 #LungCancer #RadOnc #ASCO25
In a new study, researchers from @BrighamRadOnc and colleagues used an #AI tool to help predict relapse of pediatric brain cancer. The study was published in @NEJM. Read more: massgeneralbrigham.org/en/about/newsr… doi.org/10.1056/AIoa24… @BenjaminKannMD
11/ The model and code are open-source 🔗. 🤖Code/Model: github.com/AIM-KannLab/Te… 📰Paper (free access link): ai.nejm.org/stoken/default… 🗞️Press release: massgeneralbrigham.org/en/about/newsr…