Artem Khan
@ArtemAKhan
Graduate Fellow in the Birsoy Lab @RockefellerUniv | BIF PhD Fellow | Previously: Princeton '21
I am thrilled to share that our recent study on the development of a metabolic gene function discovery platform is now online on Nature Genetics. nature.com/articles/s4158….
When #AlphaFold2 came out, we wondered: Could it help us understand how enzymes evolve? So we tried it—and it worked! nature.com/articles/s4158…
Excited to share my first work in @junyue_cao lab describing next generation, imaging free spatial transcriptomics-“IRISeq”. With IRISeq, we are able to perform scalable spatial transcriptomics analysis for various tissue sizes and adjustable resolutions..
Thrilled to introduce IRISeq, a scalable, cost-effective and imaging-free spatial genomic technique for mapping mammalian brain aging, developed by incredible Abdul @Abdul_Squared and Weirong from our lab at @RockefellerUniv! biorxiv.org/content/10.110…
My lab's first paper is out in @Nature. We show that lipoprotein uptake protects tumors from ferroptosis by delivering the lipid antioxidant α-tocopherol. Surprisingly, tumors use sulfated glycosaminoglycans—not canonical receptors—to capture lipoproteins. nature.com/articles/s4158…
I'm thrilled to share our new #bioRxiv preprint from @junyue_cao lab at @RockefellerUniv! We present PerturbFate, a high-throughput single-cell CRISPR platform profiling nascent/pre-existing RNA, steady-state RNA & chromatin accessibility. biorxiv.org/content/10.110…
Happy to share our most recent review on mitochondria-organelle metabolic communication with @YatrikShahLab and @LyssiotisLab!! We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals! sciencedirect.com/science/articl…
Excited to share our perspective on solute carrier transporters - gatekeepers of metabolism sciencedirect.com/science/articl… @KivancBirsoy @YuyangLiu1996 @gadmark @TimCKenny @CellCellPress @RockefellerUniv
A novel platform for identifying metabolic gene functions from @KivancBirsoy has already revealed interactions between proteins and metabolites that are fundamental to cell metabolism. @NatureGenet #RockefellerScience rockefeller.edu/news/36160-new…
New work from our lab’s genomics guru @ArtemAKhan with @egamazon. Artem generated a new platform for metabolic gene discovery and identified the mitochondrial choline transporter. @RockefellerUniv @NatureGenet nature.com/articles/s4158…
Following up our work describing FLVCR1 as a high affinity choline transporter @KivancBirsoy @ArtemAKhan, excited to share our recent work in close collaboration with @Yeeun_Jecy_Son @HiteLabMSKCC describing the structure and mechanism of action of FLVCR1! nature.com/articles/s4158…
Congrats @beccatimson for generating a mouse model to study GSH limitation in vivo. @RockefellerUniv sciencedirect.com/science/articl…
(Thrilled to have my first Twitter Thrill) Thrilled to share my first paper published today @ScienceMagazine. How does a cell monitor metabolic homeostasis across so many subcompartments? We tried to offer a hint by looking at GSH in mitochondria. science.org/doi/10.1126/sc…