Junyue
@junyue_cao
Finally out in @ScienceMagazine! Utilizing the cost-effective EasySci to profile 21 million single-cell transcriptomes across five life stages and diverse sexes/genotypes, we reveal aging as distinct, development-like transitions, with dramatic cell population changes in specific…
What if 1 million scRNA-seq libraries can be prepared within $1k? Here we go 👉 21 million cells from 623 mouse tissues, spanning 5 life stages & 3 genotypes, all in a SINGLE study by ONE remarkable student Zehao @Tommyz626 from our lab @RockefellerUniv! shorturl.at/epsz7
Congratulations to Rockefeller’s #classof2025!!! #PhDone 🔬🎉🧬
Interested in #singlecell and #spatial techniques for aging? Don’t miss @junyue_cao’s (Assistant Professor, @RockefellerUniv) talk at The Festival of Genomics & Biodata in Boston! Register today: hubs.la/Q03kC50b0 #FOGBoston
Our new study, published on Neuron, shows how Alzheimer’s disease impact the whole body at the single cell level. Led by @YeJin_YeahGene and @TzuChiaoLu. cell.com/neuron/abstrac…
#Alzheimers disease not only affects the #brain. @HongjieLi5 Belen lab @YeJin_YeahGene @TzuChiaoLu et al show it also impacts the whole body. @NeuroCellPress @bcmhouston @bcmgenetics @BCMGradSchool @TCHResearchNews bcm.edu/news/study-rev…
Today in @Nature, we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas. We built an interactive browser to explore the spatial data: walshlab.org/research/corte… Paper link below👇
We are looking for a research assistant to join the lab and work on spatial genomics. Please help spread the word—thanks! careersearch.stanford.edu/jobs/life-scie…
Excited to share our first anti-aging intervention study, led by brilliant Zehao @Tommyz626, Alex @alexepstein_bio, and Chloe @chloe__schaefer from our lab at @RockefellerUniv! With a cost-effective spatiotemporal analysis pipeline, we identified the aging-associated cell…
Why do many aging interventions come & go, yet Caloric Restriction (CR) remains a robust pillar, extending healthspan across species? Its benefits are even noted in ancient eastern texts like The Yellow Emperor’s Classic of Internal Medicine!
Many thanks to @RockefellerUniv , the Center for Integrated Cellular Analysis (@cegs_ica ), the Mathers Foundation, and Melanoma Research Alliance for the great support! Also, our combinatorial indexing-based approach is an addition to the growing toolkit of high-content CRISPR…
Excited to share our new preprint led by fantastic graduate student Zihan @xu_zxu! We introduce a highly scalable PerturbFate approach that co-profiles single-cell nascent & steady-state RNA + ATAC + sgRNA to uncover the convergent cell-state dynamics across diverse CRISPR…
I'm thrilled to share our new #bioRxiv preprint from @junyue_cao lab at @RockefellerUniv! We present PerturbFate, a high-throughput single-cell CRISPR platform profiling nascent/pre-existing RNA, steady-state RNA & chromatin accessibility. biorxiv.org/content/10.110…
It was a lot of fun presenting my poster at the late breaking session of #AACR2025, such an inspiring experience! Grateful for all the great conversations 😊
Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day on Friday 4/25. All talks will be live-streamed (no registration required) at satijalab.org/scgd25
We're incredibly excited to share our new method, Paired-Damage-seq, out @naturemethods today! This technique allows us to jointly analyze oxidative DNA damage and SSBs with RNA, all at the single-cell level (1/5). nature.com/articles/s4159…