Michael Kosicki
@michaelkosicki
Postdoc in Developmental Enhancerology, Embryo Engineer, Former Allele Hunter, Film Buff Without a Cause, Staunch Believer in Sentence Case.
nature.com/articles/s4158… Wow! 1,700 transgenic mice for the most comprehensive enhancer characterization ever. Leo and Axel never cease to amaze!
Our preprint describing the Range Extender element, which is required and sufficient for long-range enhancer activation at the Shh locus, is out in @Nature. nature.com/articles/s4158…
How do enhancers work over distances that sometimes exceed megabases? Excited to share our work led by @gracecbower where we uncover a unique sequence signature globally associated with long-range enhancer-promoter interactions in developing limb buds: biorxiv.org/content/10.110… 1/
Our Issue 07 launch party in San Francisco was a smashing success. 🏏 Thanks to everyone who came and played Biology Trivia. Winning teams got copies of our DNA books, hats, and posters. It was a really fun time! See you in the fall, in Boston, for the next one. :)
Range extender mediates long-distance enhancer activity nature.com/articles/s4158…
Postdoc position opening in my group! Research projects: pangenomes for diverse organisms, genome evolution, biocomputing, language models. Please reach out if interested!
We’re @BlaineyLab sharing a major update to CROPseq-multi, our versatile system for CRISPR screens that is compatible with individual and combinatorial perturbations, diverse SpCas9-based technologies, and multiple high-content, single-cell readouts. biorxiv.org/content/10.110…
Can an AI model predict perfectly and still have a terrible world model? What would that even mean? Our new ICML paper formalizes these questions One result tells the story: A transformer trained on 10M solar systems nails planetary orbits. But it botches gravitational laws 🧵
I'm super excited to share that I will be joining the Department of Biology at @Stanford as an Assistant Professor in October 2025! I’ll also be a member of the Stanford Stem Cell Institute @CellStanford. Incredibly grateful to be starting my dream job!🧠🧬🖥️
This a really exciting leap forward for genomic sequence to activity gene regulation models. It is a genuine improvement over pretty much all SOTA models spanning a wide range of regulatory, transcriptional and post-transcriptional processes. 1/
Happy to introduce AlphaGenome, @GoogleDeepMind's new AI model for genomics. AlphaGenome offers a comprehensive view of the human non-coding genome by predicting the impact of DNA variations. It will deepen our understanding of disease biology and open new avenues of research.
I am thrilled to announce that I will be starting my own lab at NYU Biology Jan 2026! Soon enough I will be recruiting postdocs and students! Please reach out if you are interested with a CV and description of your research or if you know of people who could be interested!🧬🦊
Hey y'all, I may be unemployed starting from October. If you have any leads on biotech / postdoc positions in the German-speaking part of Switzerland, I'd greatly appreciate a message. I'm great with Data Analysis, Molecular Biology, and Teaching. (Plz RT) timothyfuqua.com
How do non-coding variants in enhancers cause human disease? Here, in my main PhD work with @evgenykvon, we uncover a surprising mechanism, with generalizable implications for human genomics. tinyurl.com/89tdkevu n/