Yifan Yang
@y1fanyang
Quantitative biologist who studies physiology & evolution, PhD on aging, interested in history, philosophy of science & politics.
Thrilled to share a new paper with @UriAlonWeizmann , “Compression of Morbidity by Interventions That Steepen the Survival Curve” where we reveal an unexpected link between healthspan and uniformity of lifespans. (1/6) nature.com/articles/s4146…

"Pregnancy’s true toll on the body: huge birth study paints most detailed picture yet" Our study highlighted in @Nature News nature.com/articles/d4158…
Now in French and Spanish - our pregnancy paper is highlighted also in @Le_Figaro and @el_pais sante.lefigaro.fr/medecine/comme… elpais.com/salud-y-bienes…
The third edition of my textbook, Nonlinear Dynamics and Chaos, was published today. You can preview the first 68 pages on Google Books, or take a look at the preface below to see what's new. The main new thing is a chapter on the Kuramoto model! Hope you enjoy it.
We have a new preprint up. This one is a hypothesis paper, addressing one of the bigger unanswered questions that people have been asking me for the last 15 years: why has complex multicellularity only evolved in eukaryotes, never in prokaryotes? 1/33 biorxiv.org/content/10.110…
Our recent work is now published!
Damage dynamics in individual E. coli cells as they age explains why identical cells die at different times. Amazingly, damage follows a stochastic equation found also in mice. Aging may be universal in its fundamental dynamics. #qbio #aging disq.us/t/4ftdprd
Our paper on how a significant fraction of bacteria keeps growing many generations at lethal concentrations of antibiotics, and how this contributes to resistance development, is freely available at PNAS pnas.org/doi/10.1073/pn…
Circuit to target approach defines an autocrine myofibroblast loop that drives cardiac fibrosis biorxiv.org/cgi/content/sh… #bioRxiv
Congratulations @ThomasJulou
Growth-rate controls the sensitivity of gene regulatory circuits. Sometimes the most profound insights are those that seem obvious in hindsight. I believe this work of @ThomasJulou is one of those. Check it out. And here's a thread to whet your appetite. biorxiv.org/content/10.110…
Correct.
Friends, some fact checking. It appears that COVID casualties are not so much an "age problem" but an approx. equal increase in mortality across all age groups; pple are dying IN ~PROPORTION to their hazard rate. As if the force of mortality went up >15-20% across. Correct?
Israel data showing the decay of vaccine efficacy over time. Y-axis is cases per 1000 from July 7 to Aug 10, for unvaccinated, and for people vaccinated at different times Cases are higher in those vaxed earlier Despite world-data caveats, this seems quite compelling