Steven Shuken
@stshuken
Postdoc in the Gygi Lab at Harvard Medical School, PhD from Wyss-Coray Lab and Burns Lab at Stanford. Mass spec, chemical biology, brain aging, Alzheimer’s.
The NIH notified me yesterday that there is currently no policy that supports applying for a R00 that is associated with a terminated K99. So now, both the postdoc K99 (Harvard, $250k) and the R00 (non-Harvard institution TBD, $750) are BOTH effectively terminated.
Harvard notified me today that this K99 grant is terminated.
How are big proteins washed out from CSF, if they can’t go through the glymphatic system? Here is how: our new finding on glymphatic bypass || nature.com/articles/s4159… Congrats @Drieu_Antoine and Ben Plog and thank you to our many collaborators!
People have asked about how MAP-MS works so here's a tweetorial on @teerap16's new preprint: biorxiv.org/content/10.110…. MAP-MS takes advantage of parallelization in a trapping MS, collecting Orbitrap MS1s with 2x the dynamic range by differentially amplifying parts of the ion beam.
it's interesting how many things in computation follow this pattern
This interview from the Soledad O'Brien Show captures some of the issues for women's health and our lab's cancer research affected by the termination of federal grants at Harvard and elsewhere youtube.com/watch?v=dtjZPt… @harvardmed @AACR
The 2026 Chemistry Faculty Jobs List has 4 tenure-track positions: docs.google.com/spreadsheets/d… #facultychemjobs Faculty, if you know of tenure-track positions that we should be listing, or see an error, please e-mail us at [email protected]
.@SecKennedy - thank you so much for your broad support for gene editing and gene therapies as well as recognizing the importance of Baby KJ’s story and the potential that CRISPR base editing therapies hold for patients with severe genetic diseases. I’m thrilled you have publicly…
Thursday morning, I had the privilege of speaking with the Muldoon family, whose 10-month-old son, baby KJ, was discharged Wednesday from @ChildrensPhila. Baby KJ was diagnosed with a rare urea cycle disorder and received a first-of-its-kind personalized CRISPR gene-editing…
DOGE employee says "I personally was pretty surprised, actually, at how efficient the government was," fraud was minimal, and abuse was "relatively nonexistent" npr.org/2025/06/02/nx-…
If you're going to #ASMS2025, don't miss these presentations from members of the Gygi lab! You'll learn about TMT, chemoproteomics, GoDig for targeted proteomics, leveraging @HMSBioPlex for drug discovery, new instrumentation, and much more! @edhuttlin @stshuken @AmandaLSmythers
At least 350 @harvardmed grants were among those terminated such as studying antibiotic resistance, identifying early precursors of breast cancer, breaking barriers to deliver effective drugs for Alzheimer's, and researching cures for ALS. ⬇️1/4 abcnews.go.com/US/350-harvard…
Thank you to @stshuken, @davidasinclair, @baym, @MichaelMDesai and @BruggeMe for taking the time to speak with me about their research and what the #HarvardUniversity grant terminations mean for them. 4/4
I was quoted in this very well done story by @MaryKekatos at @ABC highlighting some of the grants that were tragically and needlessly terminated including mine. abcnews.go.com/US/350-harvard…
retweeting bc I learned that posting on a friday afternoon is not a smart move. Please share widely and encourage others to reach out if they would like to be interviewed! Two more episodes of the podcast coming soon with @drrachelmarsh and @stshuken ! shorturl.at/sAPUb
Heading into the weekend by sharing the second episode of my podcast Science Amplified, where I interview scientists like @ScienceYael whose funding has been cut, either temporarily or permanently. open.spotify.com/episode/1YZTuu…
Happy to share the peer-reviewed and updated version of our work on OrthoRep-driven evolution of aaRSs for genetic code expansion with unnatural amino acids. Congrats to @yuichi_furuhata, a true master bioengineer, on leading this excellent work! nature.com/articles/s4146…
“One of the biggest tragedies I've observed in my professional life.” @davidrliu, winner of the @brkthroughprize in Life Sciences and professor at the @broadinstitute and @Harvard, describes the cost of government cuts to science research at universities. @WalterIsaacson
Can’t imagine what international students at Harvard are going through It’s hard enough moving overseas in pursuit of higher education & training … couple that with being entirely unwanted by the government
Automating experiments with AI is going to be really hard because automation is way less about high-dimensional Bayesian optimization than it is about figuring out why there are bubbles in your syringe pump line