George Sflomos
@sflomos
Cancer Researcher passionate about Lobular Carcinoma, Preclinical Oncology, Discovery Science & Advocacy @LobularBCA Member ECR Council @EACRnews
I'm thrilled to have been part of a successful collaboration between @CBrisken and @ChristineDesme2 labs, which has led to a key publication on #metastatic cancer. Great teamwork on this challenging project has led to crucial data that cannot be obtained otherwise #lobular
Proud to present our post-mortem tissue donation program #UPTIDER dedicated to advance research on metastatic breast cancer! rdcu.be/dFCor @GeukensTatjana @MaxiMDpath @VanBaelenKaren @FendtLab @DiLa_lab @kevinpunie @HansWildiers #FRichard #GFloris #bcsm @OncoAlert
Why should we stop lumping invasive lobular carcinoma (#ILC) in with invasive ductal carcinoma (#IDC)? 🤔 Because they're not the same disease!! and treating them like they are is hold back progress. 🔬 For 3 years, we at @MDAndersonNews, in collaboration with @BostonGeneCorp,…
Neuronal transfer of mitochondria to tumor cells promotes metastases. Transfer induced metabolic reprogramming of the recipient cancer cells, which inc'd their capacity for oxidative respiration. They gained metabolic advantages and resistance to stress. nature.com/articles/d4158…
EMT and cancer: what clinicians should know doi.org/10.1038/s41571…
Cancer associated fibroblasts (CAFs) have been implicated in the pathogenesis of tumor #cachexia through their ability to modulate inflammation, metabolic reprogramming, and immune responses. Learn more in this new review! 📚 bit.ly/3GOT8nC
Stellar postdoc @DebolinaGanguly and I wrote this spotlight in for a super cool paper on the systemic effects of metatasis in breast cancer. The organ of metastatic disease has a BIG impact! Highly recommended paper in @Cancer_Cell secure-web.cisco.com/1be_LDSMLB9GnZ…
More female scientists, entrepreneurs and influencers are entering the longevity space. Their study of hormones and ovaries could unlock the key to a longer life for everyone. on.wsj.com/44BixKN
We know Mammograms can miss up to 50% of Cancers in Dense Breasts. No woman should have to wait until after a Diagnosis of Breast Cancer to find out that she has Dense Breasts and her Tumour was missed on previous Mammograms but this is what's happening!
Kudos to Journalist Lucy Elkins @DailyMail this article on #BreastDensity and the assoc #Breastcancer and Screening risks for Women who have #Densebreasts Women should be notified about their Breast Density with their Mammogram results @Lucyelkins1
My Daily Medication has been discontinued in Ireland @UCANIRELAND *Femara* manufactured originally by @NovartisIreland is now unavailable to 1000's of ER+ #Breastcancer Patients #AromataseInhibitor @IMFNews @HSELive @IrishCancerSoc imfmedia.ie/medicines-avai…
What a fascinating thread!
1/ Why is Ki-67 called Ki-67? And why am I attaching a photo of this beautiful city to the tweet? If you work in pathology or oncology, you’ve likely come across Ki-67 many times. But where does the name come from? A short 🧵 on the origins, function, and significance of Ki-67.…
I've spoken, written or read about Breast Density Risk everyday since 2016 when I began Neoadjuvant Chemotherapy for delayed diagnosis 7cm Stage 3c invasive tumour missed on my Screening Mammogram 6 months earlier. 10 years on @NSShse still don't tell Women
Yes. The time is now. Vaccines to treat and prevent cancer. jci.org/articles/view/…
Important new research from one of our Cancer Grand Challenge’s teams could help to improve cancer treatment choices in the future. While many cancers can now be targeted using precision therapies, chemotherapy remains a key way to treat some cancers and saves many lives every…
Great news for the patients! Congratulations to the team!
The FDA granted accelerated approval for our medicine to treat relapsed/refractory #multiplemyeloma after at least four prior lines of therapy. This milestone reflects our relentless commitment to make a meaningful impact in the lives of people living with multiple myeloma.
🚨Read this REVIEW published @NatureCancer ! 'The tumor microenvironment’s role in the response to immune checkpoint blockade' ✏️By Vassiliki Boussiotis and co-authors 🔗nature.com/articles/s4301…
The Molecule Behind Exercise’s Anti-Aging Effects *Today's letter (link in 6/6) reviews a new paper in @CellCellPress published 2 days ago. And includes a shoutout to someone special. 💪1/6) Nothing matches the health benefits of exercise. It’s the closest thing we have to a…
Ahh, visiting other labs. Back in my youth, we would just go places and do things. Nobody asked questions, MTAs and TTOs did not exist, and science proceeded 10x more rapidly. Today everybody frets about IP rights which will never generate any $$$, and everything stands still.
Excited to share our latest pre-print “Soluble E-cadherin Drives Brain Metastasis in Inflammatory Breast Cancer” led by the outstanding Xiaoding Hu, an instructor in my lab. #Breastcancer #Brainmetastasis #IBC #Ecadherin #ReactiveAstrocytes #CXCR2 👉 biorxiv.org/content/10.110…
Even CDK4/6 inhibitors can have uncommon side effects like vitiligo. #mascc25
Fantastic power summary by Dr @mfrimawi on HER2+ Breast Cancer and lessons learnt from recent trials. #bcsm @bcmhouston @BCMCME @BCMCancerCenter @BCM_CancerEd