Fritz Sedlazeck

Reply to: Is Gauchian genotyping of GBA1 variants reliable? | Communications Biology. After a long wait, our response to criticism of Gauchian for GBA analysis in ⁦@illumina⁩ WGS is finally published nature.com/articles/s4200…

Stayed offline too long.. Several key papers came out (thanks to my group & great collaborators), thankful for great consortia meetings, might have a position in my lab opening, new lab homepage: fritzsedlazeck.github.io oh and got tenured (I know perfect timing ;)). Thanks all

Last call for #bioinformatics #hackathon @BCM_HGSC Aug 27-29. Register: fritzsedlazeck.github.io/blog/2025/hack… Projects range from TR, SV to pangenomcs, metagenomics etc. Projects will be published in F1000. With support from @dnanexus @SMaHTnetwork @GREGoR_research #openscience #genomics

Come join us on our SV, graph genome hackathon August 27–29, 2025: fritzsedlazeck.github.io/blog/2025/hack… Seats are filling up! It will be great opportunity to work together on some prototypes. We will publish them together in F1000. @RiceUniversity @bcmhouston #bioinformatics #openscience

🧬 Online course: Structural Variant Detection and Comparison with @sedlazeck & Luis Paulin 🗓 1–3 Dec | Learn to detect, filter & compare SVs from short/long reads @illumina @nanopore @PacBio physalia-courses.org/courses-worksh…

🎉 Congratulations to our Early Career Researcher Pilot and Feasibility Awardees! 👏 Yilei Fu – @sedlazeck 👏 Cheuk-Ting Law – @KathleenHBurns 👏 Yang "Young" Zhang – @Zonglab 👏 Elliot Swanson – @stergachislab 👏 Andy Russell – @insitubiology 👏 Hang Su – @broadinstitute

🚨 Calling all structural variant wranglers! Join us August 27–29 at Baylor College of Medicine with Rice University for the 7th Pan-Structural Variation Hackathon in the Cloud. 🗓️ Save the date: August 27–29 📍 Baylor College of Medicine + Cloud 🔗 fritzsedlazeck.github.io/blog/2025/hack…

Sniffles2 improves SV detection across long-read platforms. 🧬 It's faster, more accurate, and even detects mosaic SVs in bulk data—a major boost for somatic variation research. Uncover the science behind it: pmc.ncbi.nlm.nih.gov/articles/PMC11…

1/ 🧬 A Hitchhiker’s Guide to Long-Read Genomic Analysis is out now @genomeresearch! This mini-review walks through the latest advances in long-read DNA sequencing — from assemblies to variant calling to epigenetics. Link 🔗 genome.cshlp.org/content/35/4/5… 🧵👇

Do you have an interesting benchmark experiment? We wanna hear about it! Special issue in @GenomeBiology live now: biomedcentral.com/collections/CO… Submission Deadline: 28 January 2026 #bioinformatic #genetic #genomics please share with your peers!

Call for papers - Benchmarks v2.0 biomedcentral.com/collections/CO…

Already 30+ registered for our 7th Structural Variants, Graph genomes #bioinformatics #hackathon: fritzsedlazeck.github.io/blog/2025/hack…… Registration closes 10th of Aug! Groups will work on interesting topics that will be published in F1000. @BCM_HGSC @BCMFromtheLabs @RiceCompSci

Come join us at our 7th #bioinformatics #hackathon @BCM_HGSC @BCMFromtheLabs around Structural Variants, Graph genomes & many related topics: fritzsedlazeck.github.io/blog/2025/hack… Groups will work on interesting topics that will be published in F1000. Registration closes 10th of Aug!

Call for Papers! @genomeresearch is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. @giladevrony, @EAliceLee2, and @R_Rahbari. tinyurl.com/Call-for-paper… #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism

SPECIAL ISSUE Part 2! This month @genomeresearch publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches. tinyurl.com/Genome-Res-35-4

🚨 Course alert! Structural Variant Detection & Comparison with @sedlazeck & @lfpaulin 🧬 Learn to identify & analyze germline/somatic SVs using short & long reads @nanopore @PacBio 📅 Dec 1–3 👉physalia-courses.org/courses-worksh…