Jesse Rowley
@rowleyresearch
Scientist at the University of Utah studying #platelets, megakaryocytes, and gene expression. All views expressed are my own.
The Rowley Lab (plateletlab.com) is hiring post-docs! Are you interested in mitochondria, megakaryocytes, platelets, hematopoietic stem cells, or CRISPR/CAS9 functional screens? Message me or apply at utah.peopleadmin.com/postings/183682 .
The In-Press Preview of @alison_livada work is online jci.org/articles/view/… A lot of work went into her paper, finished just in time to return to the MD portion of her studies.
Blocking a relatively unknown #cytokine creates a fountain of youth. #ForeverYoung nature.com/articles/s4158…
BDUC (bleeding disorder of unknown cause ) patients show reduced platelet adhesion/ thrombus formation.➡️ To diagnose BDUC, platelet light transmission aggregometry should be performed as a minimum assessment. Platelet transfusions can be a potential treatment option.
On #Cover #July New @isth SSC paper on bleeding disorders of unknown cause @MahaOthman8 @nikmutch @@Mtl_PlateletLab jthjournal.org/action/showPdf…
Want to learn about platelets, megakaryocytes, hematopoietic stem cells, RNA-seq, CRISPR, and high throughput functional screens? We're hiring a post-doc: utah.peopleadmin.com/postings/164554
Our new article on factors influencing Platelet assays (e.g., blood draw time, time to test, age, sex, medications, technician, seasonality) and inter-assay correlation in >3,400 people is now online: sciencedirect.com/science/articl… @RPTHjournal @isth
Morning everyone! Pleased to share a detailed protocol of our bone marrow organoid approach in @NatureProtocols : nature.com/articles/s4159….
Pre-print of our work led by Chen Li is online at Circ Res. Chen put a lot of data together to identify new ways platelets regulate monocyte immune responses. ahajournals.org/doi/epdf/10.11…
Important step forward in #PrecisionMedicine - Platelet RNA Biomarker of Ticagrelor responsive genes Is associated w #platelet fxn and #cardiovascular events - Collaborative effort betwn @DukeCardiology and @NYUCVDPrevent @TessaJBarrett @nyulangone ahajournals.org/doi/10.1161/AT…
Jacob et al found that #MFN2 promotes #mitochondrial fusion in #megakaryocytes to maintain #platelet lifespan, & impacts function, ischemic #stroke, & #lung injury in mice at ahajrnls.org/3S6Skft @rowleyresearch @racampbell04 @FrederikDenorme @IntmedAbel
Here is the next one in @CircRes congrats to @rowleyresearch @jacob_shancy @racampbell04 @RhondaSouvenir @UU_MolecularMed showing #mitochondria dynamics via MFN2 regulating platelet activity. A good week for papers. bit.ly/4aHT8Qo
Who are the leaders in the field of inherited platelet disorders? This is what ChatGPT said. Paul Bray is retiring this month. He has been a stellar mentor and I have been fortunate to work with him. Shout out to the others too for their work recognized by AI :)
The PAR4 Thr120 variant influences platelet-neutrophil interactions and stroke outcomes: buff.ly/3sZDTRn @racampbell04 @FrederikDenorme @MaryCushmanMD #Hematology #Neuroscience
Posting this again - for postdoctoral candidates interested in both dry- and wet-lab research with a focus on platelet biology. Rutgers application link here: jobs.rutgers.edu/postings/211753 (written statements requested should be <450 words).
Detailed post here for recruiting to my lab @BMERutgers, a very interdisciplinary & collaborative department that educates a diverse student body. bit.ly/plateletomelab Please share with your network & reach out if the role is of interest! #platelets #postdocjobs #careers
Glad to see Dr. Abel, my former K award co-mentor, featured in Cell. He is an excellent scientist and mentor. cell.com/cell/fulltext/…
. @FrederikDenorme knocks it out of the park once again with a knock-in model investigating a (druggable) key gene variant leading to ⬆️platelet activation ⬆️NETs and ofc ⬆️stroke risk. Definitely highlights the huge need for greater #diversity in clinical trials
Outstanding talk from Brinkhous finalist @FrederikDenorme at #vasculardiscovery23. Great session with great talks from @Colin_E_Evans @WSteveHur @AmilyLiGuo
Happy to see Tony Zheng's PhD thesis work now online @BloodAdvances - offering some new insights into procoagulant platelet generation and inhibition in dyslipidemia @OHSUSOM @OHSUCardFellows @OHSUCardio @OHSU_BME @OSUPharmacy ashpublications.org/bloodadvances/…
Schütte et al demonstrate the pivotal role of platelet-derived miRNAs in cardiac remodeling after #IR injury in mice. Learn more at ahajournals.org/doi/10.1161/CI… including a review discussing the latest promising platelet #miRNAs & their potential implications in CVD.