Reema Baskar
@reemabaskar
Studying cellular plasticity in cancer, immune system through epigenetics lens. Hybrid scientist. Biotech consultant. @imperialcollege @stanfordcbio
🧵 (1/8) Today, @BenOberlton and I are excited to share the preprint of our work on: A comprehensive multi-omic study of human gliomas, spanning diagnosis, treatment, and recurrence. We address the longstanding challenge of developing effective therapies for gliomas, which have…
Thrilled to share our latest publication! Our study on IKAROS and antigen escape relapse after CAR T cell therapy is now out! We found that low IKAROS expression in leukemia cells is linked to a higher risk of antigen escape relapse. doi.org/10.1038/s41467…
I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) biorxiv.org/content/10.110…
The second annual Spatial Biology Workshop is just two weeks away! This free event will showcase the power of spatial techniques to answer biological questions. We'll be showcasing new methods for data generation and analysis, as well as the novel findings they enable (1/x)
New #DeveloperStories episode! Today we chat with scientist @reemabaskar from the Genome Institute of Singapore. I love this episode because we have so much fun - talking about cellular plasticity/epigenetics via the story of Sally the Cell.🧪 👉 Spotify open.spotify.com/episode/3zKlh1…
Congrats Rashmi! Awesome paper on better polymers for tricky markers!
Excited to share our work from @MikeAngeloLab Synthesis, Characterization, and Applications of a Superior Dendrimer-Based Polymer for Multiplexed Ion Beam Imaging Time-of-Flight Analysis | Biomacromolecules pubs-acs-org.stanford.idm.oclc.org/doi/10.1021/ac…
Really amazing work, congrats @Dunja_Mrdjen!
Thrilled to share the preprint from my postdoc work in the @Bendall_Lab with @MikeAngeloLab and Thomas Montine at @StanfordMed looking at human microglia in situ in #aging and #Alzheimers disease by multiplexed proteomic imaging! shorturl.at/agCN0
We're excited to announce that the 2nd annual Spatial Biology Workshop will be taking place August 28th-30th at Stanford. The workshop will cover new techniques and tools for generating and analyzing spatial data, as well as new biology discovered using spatial methods.
Amazing work by @YeEun_Kim__ in decoding important hematopoietic biology using high dimensional tools!
Excited to share my preprint with @Bendall_Lab and @WJGreenleaf on novel human lymphoid progenitors! Turns out they had been misidentified as myeloid progenitors thus far. Check out how we revealed their true identity in the tweetorial below 🧵biorxiv.org/content/10.110…
Feeling extremely grateful to be part of Stanford Pathology DE&I committee and its tremendous efforts and initiatives! As the first event of the season, we organised a fair where various booths highlighted various issues in Academia and Medicine. It was a huge success!!
With almost 100 attendees at our first DE&I fair, we touched quite a few people with our message of diversity, equity & inclusion covering women in STEM, disability, belonging, fair recruitment, respectful work culture, mentoring & peer support, global health @StanfordPath
Very excited to share SELMA, a computational method we developed for ATAC-seq & DNase-seq bias estimation, recently published in @NatureComms spearheaded by @ShengenShawnHu w input from @zozolaki @liul_stoch_stat @guertinlab Ke Deng & Tingting Zhang nature.com/articles/s4146…
Very happy to announce that I will be opening my lab at the Genome Institute of Singapore @astar_gis in February 2023! Looking forward to joining the outstanding group of scientists at GIS stuartlab.org
Ever wondered how the 'happy pill' Prozac impacts the brain? We did too! Delighted to share our study on the effects of fluoxetine (Prozac) on 27 different rodent brain areas. Paper is out in Molecular Psychiatry & available for free reading. nature.com/articles/s4138… A thread 👇🏾
🔔Proud and excited to share our latest preprint! We asked this simple question: do TADs really act as strong boundaries or can functional enhancer-promoter interactions be established across TAD boundaries? biorxiv.org/content/10.110… A 🧵on our main conclusions: (1/n)
Very excited to share our work with @MattRijn @johnhickey22 @GuolanLu @luca_bogdan @GarryPNolan @BrubakerSky @kidzik Rob West @Stanford spatially dissecting macrophage niches in human breast and colon benign and tumor tissue. biorxiv.org/content/10.110…
I spend way too much time scrolling and I finally have something to help me curate my Twitter intake - an excellent app by @tjburns08! Great write up of the motivation behind it and it’s going to be useful for most Twitter users.
I made a "map view" of the news using an AI language model (all-mpnet-base-v2) and UMAP. It pulls and maps tweets from various news sources daily. My goal is to make checking the news more efficient and to show connections between stories. Check it out! news2vecmap.herokuapp.com
Awesome tool for multiplexed imaging data, congrats @CandaceCLiu !!
Excited to share the latest preprint with @MikeAngeloLab! While imaging studies often focus on cell objects, images capture significant info outside of cells. Enter Pixie, a pipeline for the quantitative annotation of both pixel and cell level features🧵biorxiv.org/content/10.110…
Cell Patterns interviewed David and I for the "People of Data" article in their August issue! We talk about our journey as (data) scientists, how the HSS-LDA project started, and more. Check it out to learn a bit more about us beyond the research! cell.com/patterns/fullt…
Excited to announce our first ever MIBI workshop! We'll be talking about the new tools our lab has developed for generating, processing, and analyzing MIBI data. We'll also be going over our workflow for reagent validation, panel design, and troubleshooting pesky antibodies.
Happy to see more powered studies on female reproductive health issues
Finally, it is out! nature.com/articles/s4155… I am glad to be part of this AMAZING teamwork at @TheRobsonLab @jacksonlab @delucianomd @uconnhealth for their dedication and contribution. We are also grateful for the tissue donation and funding which made this study possible! 1/13🧵