Birgitt Schuele (She/her)
@SchueleLab
Making a difference for Parkinson's disease research. My research improves patient care by unraveling the causes of neurodegeneration. 🌈🏃🏻♀️🧑🔬
If you attend #Sfn23, check out our poster on multiplex imaging of human post-mortem brain, LRRK2, Parkinson’s disease in collaboration with @AkoyaBio and supported by @MichaelJFoxOrg
Attending #SfN23? Don’t miss our posters on how our #spatialphenotyping solutions contribute to the progress in #glioblastoma & #Parkinsonsdisease research. #SfN2023 @SfNtweets @OracleBio @abcam @Stanford @StJude @AdityaPratapa_ @Theo_BrainC_lab @TheDohertyInst @SchueleLab
New preprint on ATXN10 in Peruvian families show repeat motif patterns influence disease onset @PacBio @bionano @mario_cornejo_o researchsquare.com/article/rs-598…
Scrutinizing the KOLF2.1J iPSC line using @BionanoGenomics OGM. #OpenScience #iPSC #Genomics biorxiv.org/content/10.110…
Interested in joining our labs as a post-doc? @BrainResilience @StanfordPath @StanfordMed @Stanford_Neuro

We have an open position for a cell culture technician for an exciting new initiative to build a protein atlas for neurodegenerative diseases. Are you interested? Please see the link: phxc1b.rfer.us/STANFORD3D1Qds
New Schuele lab Tee design. Any idea what we do?

📣Please RT! Our lab @Stanford_Neuro has an immediate opening for a full-time Research Assistant studying biomarkers of neurodegenerative disease! 🔬🩸🥼 Fun & supportive training environment with fantastic colleagues! For more info & to apply visit: careersearch.stanford.edu/jobs/life-scie…
Looking forward to the Stem Cells in Neuroscience conference in Tuebingen next week! #StemCellTuebingen stemcelltuebingen.com
Our Department of Pathology at Stanford University is seeking an exceptional scientist to join us as a tenure-line Assistant, Associate, or Full Professor. @StanfordMed, @StanfordPath Please share: facultypositions.stanford.edu/en-us/job/4946…
Are you interested in publishing your latest research in the field of gene therapy for neurodegeneration with @SciReports? There is a new collection, we just launched.

Thanksgiving potluck luncheon in the Schuele lab!

We deposited a CRISPR-edited alpha-synuclein gene dosage human iPSC model with @officialatcc supported by @MichaelJFoxOrg. I hope this will be a valuable tool for #Parkinsons research community. atcc.org/blogs/2023/acc…
Congratulations to Ale Morato Torres for winning a poster prize at the Stanford Pathology retreat @StanfordPath for her in vivo work - knockdown of human alpha-synuclein as a therapeutic strategy.

New research from @DanutaSastre @SchueleLab & @StanfordMed colleagues provides proof-of-concept in vitro targeting of the SNCA gene promoter using a #CRISPR interference (CRISPRi) system to controllably repress #Parkinsons-associated alpha-synuclein nature.com/articles/s4159…
The journey has an end! Thanks for everyone who supported this study! It could have been a lot easier and faster, if we can all focus on the science! nature.com/articles/s4159…
Happy 111th birthday to this little one
My postdoc work is finally out! We used #CRISPR to lower alpha-synuclein in #Parkinsons #iPSC neurons, achieving functional recovery. #invivo work coming out soon from the team at @SchueleLab @StanfordMed pre-print here while in #PeerReview doi.org/10.1101/2023.0…
Congratulations team! Cas9 interference gene therapy enables long-term alpha-synuclein downregulation in Parkinson's pre-clinical model. biorxiv.org/content/10.110…