Meelad
@meeladamouzgar
Computational Immunology PhD student in the @Bendall_Lab with @stanfordimmuno. @StanfordBioX Fellow. Community College educated. Handstand enthusiast.
Cell Patterns interviewed David and I for the "People of Data" article in their August issue! We talk about our journey as (data) scientists, how the HSS-LDA project started, and more. Check it out to learn a bit more about us beyond the research! cell.com/patterns/fullt…
Excited to see this published! Check out Pixie, a pipeline for quantifying non-cellular features (as well as improving cell classifications) in multiplexed images. nature.com/articles/s4146…
Excited to share the latest preprint with @MikeAngeloLab! While imaging studies often focus on cell objects, images capture significant info outside of cells. Enter Pixie, a pipeline for the quantitative annotation of both pixel and cell level features🧵biorxiv.org/content/10.110…
I am thrilled to share my preprint with @Bendall_Lab that includes a new and comprehensive phenotypic atlas of human hematopoietic progenitor cells. Check out how we reconcile the diversity of human HSPCs in the tweetorial below. biorxiv.org/content/10.110…
Very excited to have our work out in @Nature today – a huge effort with @MikeAngeloLab @Inna_Averbukh @ShirleyGreenba1 @_hubmap 🤰🤰 Check it out here! nature.com/articles/s4158…
Excited to share our work from @MikeAngeloLab Synthesis, Characterization, and Applications of a Superior Dendrimer-Based Polymer for Multiplexed Ion Beam Imaging Time-of-Flight Analysis | Biomacromolecules pubs-acs-org.stanford.idm.oclc.org/doi/10.1021/ac…
Thrilled to share the preprint from my postdoc work in the @Bendall_Lab with @MikeAngeloLab and Thomas Montine at @StanfordMed looking at human microglia in situ in #aging and #Alzheimers disease by multiplexed proteomic imaging! shorturl.at/agCN0
@_hubmap @Bendall_Lab Today, we are thrilled to welcome Kanishka and Krish Kumar, our summer students. They are now keen to go into the fascinating area of spatial omics in bone marrow tissue after finishing their snacks. We greet both of you and wish you a rewarding time!
Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma dlvr.it/Smf7yn
Entire article is available here: doi.org/10.1016/j.ccel…
Systems biology manifesto!
Our review on systems immunology studies of lymphoid cells is out! We focused on discussing key single-cell papers on lymphocyte development and heterogeneity and their impacts. Lots of thanks to @Bendall_Lab and @WJGreenleaf Link for free access: authors.elsevier.com/a/1gsxd3OeyGHW…
Our review on systems immunology studies of lymphoid cells is out! We focused on discussing key single-cell papers on lymphocyte development and heterogeneity and their impacts. Lots of thanks to @Bendall_Lab and @WJGreenleaf Link for free access: authors.elsevier.com/a/1gsxd3OeyGHW…
Thrilled to see this paper out! Working with amazing collaborators makes science so much more fun @CampKatiee @CSpencerPhD. Grateful for my co-first @CampKatiee for a smooth experience. Do science with your friends! ;)
💥Very excited to share our latest work in @Cancer_Cell harmonizing WES/RNAseq from melanoma IO datasets to better understand predictors of response to anti-PD-1 therapy. Thank you @parkerici @ScienceAtBMS for supporting this herculean effort in data assembly and analysis
Deans don't lie!!!!!!!!!!!!!! Coming soon!!!!!!!!!!! 🤩 🤩 🎉 🎊 💃 💃 💃 😬
A fan of the book written by two National Academy members (@HastieTrevor, @robtibshirani) and two COPPS winners (@robtibshirani, @daniela_witten)? Love the second edition but still want more? Stay tuned for the next installment.
@daniela_witten, @lucygao, Ameer Dharamshi, and I are excited to share our new preprint (arxiv.org/abs/2301.07276). We introduce *data thinning*, a flexible framework that splits a single observation into independent parts, providing an alternative to cross-validation. (1/11)
The Bias-Variance Trade-Off & "DOUBLE DESCENT" 🧵 Remember the bias-variance trade-off? It says that models perform well for an "intermediate level of flexibility". You've seen the picture of the U-shape test error curve. We try to hit the "sweet spot" of flexibility. 1/🧵
Have you ever wondered how human lymphoid cells are actually refreshed in adult hematopoiesis? Or maybe why CD10 ‘CLPs’ really only know how to make B Cells? We have found a significant new source of multi-lineage lymphoid cells in the Human!
Excited to share my preprint with @Bendall_Lab and @WJGreenleaf on novel human lymphoid progenitors! Turns out they had been misidentified as myeloid progenitors thus far. Check out how we revealed their true identity in the tweetorial below 🧵biorxiv.org/content/10.110…
Excited to share my preprint with @Bendall_Lab and @WJGreenleaf on novel human lymphoid progenitors! Turns out they had been misidentified as myeloid progenitors thus far. Check out how we revealed their true identity in the tweetorial below 🧵biorxiv.org/content/10.110…
Excited to announce our new paper and software for multiview analysis: supervised learning with multiple sets of features. Can be used with lasso/elastic net; the idea generalizes to boosting and random forests. See tibshirani.su.domains/multiview/Coop… for a 3 min video explaining the idea.
Read a recent paper from @Patterns_CP and learn what the author @Bendall_Lab has to say about their work @meeladamouzgar @david_r_glass hubs.li/Q01lCjWb0
Day 1 of the MIBI workshop is starting now! Looking forward to a ton of cool talks. Today's talks are centered around how to generate highly multiplexed image datasets. It's not too late to register for the virtual portion: angelolab.com/mibi-workshop