Ronan O'Malley
@omalley_ronan
Many transcription factor families have evolutionarily conserved binding motifs in plants (Sanja Zenker , Donat Wulf , Anja Meierhenrich , Prisca Viehöver , Sarah Becker , Marion Eisenhut , Ralf Stracke , Bernd Weisshaar , Andrea Bräutigam) doi.org/10.1093/plphys… @ASPB #PlantSci
We're hiring! Need a microscopy wizard to help build the world’s first synthetic plant chromosome! Bring your lights, lasers, & lens-craft to characterise new artificial chromosomes. Join our ARIA-funded project at @uwanews in Perth & @plants4space. Apply: bit.ly/3GKSRSA
Preprint alert: single-cell methylation signature of autism in collaboration with @GeschwindLab. Autism-mC signal is enriched in promoters and cell-type enhancers but uncorrelated with gene expression. Led by @GeschwindLab Postdoc Katie Eyring and grad student Cuining Liu.
A Single-Cell Atlas of DNA Methylation in Autism Spectrum Disorder Reveals Distinct Regulatory and Aging Signatures biorxiv.org/content/10.110… #biorxiv_neursci
Timing and location of RNA splicing is a fascinating area of research. Alongside recent work and this amazing @NatureRevGenet review from Churchman lab @fiddle, see our report on co- vs post-transcriptional splicing and its coupling with the RNA life cycle doi.org/10.1038/s41467…
We're excited to share another work from our lab this week. We present ENTRAP-seq, the first massively parallel reporter assay to characterize protein-coding libraries in plants. Congrats to Simon, Lucas, and all other co-authors. biorxiv.org/content/10.110…
Today the Shih Lab (@LabShih) presents ENTRAP-seq, a high-throughput assay for functional screening directly in plant cells.
Happy to share our new publication out today in @NaturePlants where we quantitatively dissect synergy and antagonism that occurs during Nicotiana benthamiana transient agroinfiltration. Congrats to Simon, Matthew, Mitch and all other co-authors! nature.com/articles/s4147…
Happy to share a preprint describing my new method, Dam-IT (DamID-seq Incorporating Transcriptomics)! Dam-IT simultaneously captures TF-DNA binding, gene regulation, and chromatin accessibility from the same batch of plant cells. biorxiv.org/content/10.110…
Transcription factors instruct DNA methylation patterns in plant reproductive tissues biorxiv.org/content/10.110… #biorxiv_plants
Arabidopsis REM transcription factors and GDE1 shape the DNA methylation landscape through the recruitment of RNA Polymerase IV ... biorxiv.org/content/10.110… #biorxiv_plants
Neofunctionalized RGF pathways drive haustorial organogenesis in parasitic plants biorxiv.org/content/10.110… #biorxiv_plants
Our new study on characterizing plant DNA methylation reader proteins, led by @jon_cahn and @JamesPBLloyd, and great collaboration with the Michiel Vermeulen and @ahmillar9 groups genome.cshlp.org/content/early/…
Just out in Nature, we reveal a key molecular signature that evolution drew upon to boost photosynthesis—the process responsible for fixing CO2 (and sustaining life as we know it). Together with the brilliant @l_luginbuehl, @JoeEcker, and @jmhibber nature.com/articles/s4158…
Joe Ecker @JoeEcker, Joseph Swift @_joseph_swift, and team have revealed the genetic details of 30-million-year-old question: How did some plants evolve from less-efficient C3 photosynthesis to C4 photosynthesis? Their findings pave the way for the creation of more robust,…
🌿 Today, we remember Salk Professor Joanne Chory, a visionary plant biologist and a force for climate action. Her research revolutionized how we understand plant biology and inspired solutions to fight climate change. Joanne’s brilliant mind and passion will forever impact the…
"...here I present to you a germinated #cassava embryo that just 11 weeks earlier was a single cell in in vitro culture!" In #Profile: @Bas_Bargmann 👇 📖 nph.onlinelibrary.wiley.com/doi/10.1111/np… #LatestIssue @wileyplantsci
It is my absolute pleasure to share my incredible postdoc Dawei's @amaizeingcorn manuscript on epigenetics and aging in Arabidopsis. It is the work I am most proud of thus far in my career, and every figure has a breakthrough that we are excited about biorxiv.org/cgi/content/sh…
The convergent evolution of ectomycorrhizal lifestyles has been extensively studied within fungal lineages. The evolution of symbiosis in plant lineages remains comparatively underexplored, making this study particularly valuable … biorxiv.org/content/10.110…