Matt Kaeberlein
@mkaeberlein
Husband, father, scientist, athlete (sort of), CEO, recovering academic. Passionate about helping people and companion animals live longer, healthier lives.
Your poop habits show up in your blood. Dr. Sean Gibbins: Constipation triggers protein fermentation by gut microbes—producing compounds that harm the liver, kidneys, and heart. @mkaeberlein #guthealth #microbiome #longevity #OptiSspanPodcast
maaaaaaaaan, hahaha, this is what @PeterAttiaMD and @mkaeberlein have been saying for a few years already.
Muscle mass predicts lifespan better than BMI or weight - so get moving and get lifting
Lactose Intolerant after antibiotics? @mkaeberlein explains: antibiotics can trigger microbial “extinction events” that wipe out your lactose-digesting microbes. #microbiome #lactoseintolerance #guthealth #OptispanPodcast
I have a somewhat different take. We have useful and actionable personalized biomarkers of health today - it's just that methylation isn't one of them and direct to consumer companies will always have the incentive to cut corners regardless of the technology so long as there is…
NEW: No technology currently exists to repair damaged brain tissue and fully restore lost function. FRONT aims to enable millions with what is considered permanent brain damage to regain lost functions, including motor control, vision, and speech. arpa-h.gov/news-and-event…
I couldn’t agree more with @mkaeberlein here. These limitations are why we built PROSPR🖖🏻
What doesn’t work in longevity medicine today? Direct to consumer biological age and microbiome tests. Why do I say that? (1) The don’t measure what they claim to measure (2) They provide no information on precision or accuracy (3) There is no industry quality control (4) There…
What doesn’t work in longevity medicine today? Direct to consumer biological age and microbiome tests. Why do I say that? (1) The don’t measure what they claim to measure (2) They provide no information on precision or accuracy (3) There is no industry quality control (4) There…
BREAKING: Gero Signs Potential Multi-Billion-$ Deal to Fuel Our Mission to Stop Aging -- A few years ago, my son, aged five at the time, asked what happened to the dinosaurs. After learning their sad story, he told me he wanted to fly to the Moon and defend Earth from falling…
Are we close to having real-time wearable biological age (mortality) estimators? I think so. And Prof Jan Gruber from National University Singapore agrees. If we're right, the implications are profound. Keep an eye out for our full conversation from @LongevityDublin. It will…
Why do we age? Natural selection only prioritizes survival to reproduction—not lifelong health. @mkaeberlein on the evolutionary biology of aging. #longevity #aging #OptiSpanPodcast
Rapamycin shows lifespan extension in animals. @mkaeberlein discusses the evolutionary conservation of its benefits. #rapamycin #longevity #OptispanPodcast
Rapamycin is an FDA approved drug. It has been determined to be sufficiently safe for human use. Safe is, of course, a relative term. No intervention - drug or otherwise - is 100% free of risk. The question you should be asking is whether potential reward outweighs potential…
🎤 We are thrilled to welcome @mkaeberlein, CEO of @Optispan_Inc to the stage at the Longevity Investors Conference 2025 in Gstaad! With over 250 scientific publications and decades of work spanning human and animal longevity, Dr. Kaeberlein brings a wealth of insight into…
During my talk I specifically called out these gene therapy clinics and they way they are operating. I suggested one improvement would be an independent body that collects and aggregates the data on both efficacy and adverse events. Afterward folks from the conference shared some…
Sitting here at day 2 of @LongevityDublin feeling uneasy with the presentation from TripleHelix about what they are doing with gene therapy outside of any regulation. Then the guy starts talking about SIRT1 gene therapy, and now I'm certain they don't know what they are doing.…
Absolutely fantastic session and panel discussion on Women’s Health & Longevity at @LongevityDublin featuring @jenngarrison, Dr. Leoni Matt, @chiara_herzog, and Judith Mueller. It was exciting to see all the progress, but disappointing and disturbing to hear how uninformed and…
The #DogAgingInst funds innovative research projects, such as the @DogAgingProject and its clinical study, TRIAD. 🔍To help continue important research like #DogAgingProject and TRIAD, consider donating today at dogaginginstitute.org/donate
"This research is important to not only creating a better quality of life for canine companions, but also because it could help with understanding human aging." ➡️Read Article: citydoglosangeles.com/dog-aging-proj… ⚛️Find out if your #dog is eligible for TRIAD: dogagingproject.org/triad
Great talk from @mkaeberlein at @LongevityDublin on making dogs live healthier longer with @DogAgingProject and humans love healthier longer with his company @Optispan_Inc
Sitting here at day 2 of @LongevityDublin feeling uneasy with the presentation from TripleHelix about what they are doing with gene therapy outside of any regulation. Then the guy starts talking about SIRT1 gene therapy, and now I'm certain they don't know what they are doing.…
Two take-aways from David Furman's talk during day 1 of @LongevityDublin : (1) Trajectories of change in "aging clocks" are likely more informative than absolute age-estimates during normative aging (2) Microgravity accelerates many phenotypes of aging - perhaps accelerates…