Optispan

Founder Matt Kaeberlein explains how Optispan offers a personalized healthcare plan tailored to an individual’s health and biomarkers. With a team approach, Optispan helps people take control of their longevity journey. Dr. Kaeberlein talks more about Optispan and longevity in…

Medicine 3.0 today isn't enough - Currently, a lot of our proactive and preventative medical care is being paired with questionable diagnostics, supplements, and experimental therapies that we don't fully understand. We need more research and a better understanding of how the…

Episode 119 of the Optispan Podcast releases today! Watch it here: youtu.be/GDen2wPZro8

Medicine 2.0 has brought us a lot of progress, but we need to keep moving forward if we want to extend life and healthspan. The best way forward is to embrace proactive, preventative healthcare. Doctor Kaeberlein spoke about this at his talk at RAADFest 2025, hosted by…

Introducing: Longevity Myths Debunked! With all the noise and misinformation out there in the #health and #longevity space, it’s difficult to separate fact from fiction. But we hope these infographics, with text supplied by Optispan founder and longevity scientist @mkaeberlein…

Most humans are lactose intolerant—technically. Dr. Sean Gibbins tells @mkaeberlein: Bifidobacteria in your gut help you digest milk. Antibiotics or food poisoning can wipe them out—causing sudden intolerance. #microbiome #lactoseintolerance #bifidobacteria #OptispanPodcast

Your poop habits show up in your blood. Dr. Sean Gibbins: Constipation triggers protein fermentation by gut microbes—producing compounds that harm the liver, kidneys, and heart. @mkaeberlein #guthealth #microbiome #longevity #OptiSspanPodcast

Lactose Intolerant after antibiotics? @mkaeberlein explains: antibiotics can trigger microbial “extinction events” that wipe out your lactose-digesting microbes. #microbiome #lactoseintolerance #guthealth #OptispanPodcast

What is the microbiome, exactly? Dr. Sean Gibbins: It’s the genetic material of a microbial ecosystem. The microbiota? That’s the organisms themselves—bacteria, fungi, viruses, archaea, and more. #microbiome #microbiota #longevity #OptispanPodcast

One person took 100mg+ and saw only temporary lipid changes. No real toxicity. @mkaeberlein says: Don’t buy the fear. #rapamycin #longevity #OptispanPodcast

Just because we evolved to do it doesn’t mean it’s good for longevity. @mkaeberlein on why evolutionary assumptions might hold us back. #longevity #evolution #OptispanPodcast

Mice on rapamycin: ✅ Better insulin sensitivity ✅ More ketogenesis ✅ Higher oxygen use @mkaeberlein on the metabolic effects beyond lifespan. #rapamycin #metabolism #OptiSpanPodcast

Rapamycin or fasting? Dr. Matt Kaeberlein: In mice, rapamycin can extend lifespan 5–6x more than fasting alone. #rapamycin #fasting #longevity #OptispanPodcast

Think rapamycin shuts down mTOR? Dr. Matt Kaeberlein says: Not possible at real-world doses. No evidence of impaired healing or brain function. #rapamycin #mTOR #longevity #OptispanPodcast

Rapamycin shows lifespan extension in animals. @mkaeberlein discusses the evolutionary conservation of its benefits. #rapamycin #longevity #OptispanPodcast

Why do we age? Natural selection only prioritizes survival to reproduction—not lifelong health. @mkaeberlein on the evolutionary biology of aging. #longevity #aging #OptiSpanPodcast

Does rapamycin impair glucose metabolism? In mice, maybe. But that doesn’t mean the same thing happens in humans. @mkaeberlein explains why context matters. #rapamycin #longevity #OptispanPodcast

The dual process model of grief: Acknowledge the pain first. Then offer action. “Just go for a walk” may not help until someone feels heard. @mkaeberlein #grief #OptiSpanPodcast

Sometimes just saying the name of the person can help a grieving person. Emma Payne explains why & how. @mkaeberlein #grief #OptiSpanPodcast

"Grief is the distance between what you have and what you wish you had. "It’s the severing of a connection that defined you." - Emma Payne @mkaeberlein #grief #emotionalhealth #OptiSpanPodcast