Helena Schulz-Mirbach
@mirbachh
Metabolic engineer for a better future 👩🏼🔬. Former Bar-Even member and PhD student @erblabs 🥳🪄.
#Growth-coupled #selection just got an update ! In the last years, E. coli selection strains for #central , #amino #acid and #energy metabolism intermediates were created. So, we compiled them and revisit the core concepts of growth coupling. sciencedirect.com/science/articl…
📑📑📑#synthetic_biology @enricooorsi @mirbachh @PabloINik @erblabs present a workflow for designing versatile auxotrophic metabolic sensors for glyoxylate and glycolate detection #BiotechNatureComms nature.com/articles/s4146…
Check out this amazing work on engineering, characterizing and using six novel glyoxylate sensor strains led by @enricoorsi and @mirbachh🔥🎊🥳 Read Helenas nice post below to get the full picture.
Really happy to share that our work on constructing six glyoxylate / glycolate sensors covering a three order of magnitude concentration range is out now in @NatureComms ! 🔥 Read below to see how we developed the sensors and what they are good for 🥳. nature.com/articles/s4146…
Computation-aided designs enable developing auxotrophic #metabolic #sensors for wide-range glyoxylate and glycolate detection—spearheaded by @enricoorsi w/a choral assembly of cool collaborators @LabNikel @NatureComms #SynBio #OpenAccess nature.com/articles/s4146…
Implementing synthetic serine cycles in #Pseudomonas putida unlock methanol assimilation in our favorite bug with carbon conservation, led by @OscarPuiggene · #SynBio #MetabolicEngineering #Methanol @TrendsinBiotech sciencedirect.com/science/articl…
📢We are thrilled that our Microbes for Climate (M4C) Cluster of Excellence has been selected for the 2025 Excellence Strategy! 🥳 Together with Philipps University Marburg, we're looking forward to some exciting #microbe research! @maxplanckpress @BangeBalcony #synbio #research
I'm truly excited to announce our new publication in @Nature unraveling a central picture of the Methyl-coenzyme M reductase (MCR) activation machinery and it's strong ATP dependency - kudos to @AnujR2d2 for the fantastic illustration! LINK: nature.com/articles/s4158…
Excited to share a main project from my PhD, out now in @NatureComms! 📝 We've designed and brought to life the “CORE cycle” – a new-to-nature pathway that provides a novel route for biological CO2 capture 🦠🌱 nature.com/articles/s4146… Take a look! Thread below... 🧵
Seven Critical Challenges in Synthetic One-Carbon Assimilation and Their Potential Solutions—led by @FavoinoGiusi & @OscarPuiggene @LabNikel @FEMSmicro #Microbiology #Reviews #SynBio #Metabolic #Engineering academic.oup.com/femsre/advance…
🌿🔬How can we fix #CO2 more efficiently in biological systems? Our new study introduces the CORE cycle, a synthetic pathway that converts CO2 to formate at aerobic conditions and ambient CO2 levels! 🚀🦠 @erblabs @mpi_marburg nature.com/articles/s4146…