Pablo M. Garcia-Roves
@m_roves
Scientist, healthy living, energy metabolism, mitochondria, lifestyle, exercise, university, research.
Many thanks @davisis79 . Proud of Pau. Great dissertation. Many thanks @mardelmala, @AntonioZorzano, @Amaia_777 and @VillenaLab. And special thanks to all our collaborators that contributed to this work doi.org/10.1101/2020.0…
annualreviews.org/doi/10.1146/an… Mitochondrial Ion Channels are good candidates for drug targets.
Mitochondrial origins of the pressure to sleep | Nature nature.com/articles/s4158…
Mitochondrial age-classes expand the heterogeneity of tissue-resident stem cells go.nature.com/3Im0gsb
Mitochondrial DNA: how does it leave mitochondria? dlvr.it/TLsnZp
New study reveals targeted remodelling of the adipose tissue niche in obesity and after weight loss, highlighting potential pathways for therapeutic intervention. #ObesityResearch #Metabolism #WeightLoss nature.com/articles/s4158…
Plasma proteomics links brain and immune system aging with healthspan and longevity nature.com/articles/s4159…
pDCs drive immunopathology by sensing oxidized mitochondrial DNA | Nature Immunology nature.com/articles/s4159…
Mitochondrial control of lymphocyte homeostasis; sciencedirect.com/science/articl…
Molecular machineries and pathways of mitochondrial protein transport | Nature Reviews Molecular Cell Biology nature.com/articles/s4158…
Multi-omic analysis reveals transkingdom gut dysbiosis in metabolic dysfunction-associated steatotic liver disease go.nature.com/3TUHPNw
Use pathway-control ratios and efficiencies to quantify N-, S-, and NS-pathway contributions under convergent electron flow. Learn more 🧠👉: buff.ly/tceCZ0M buff.ly/EVVW90k #HighResolutionRespirometry #mitochondria #MitoPedia
New content online: Adipose tissue ageing: implications for metabolic health and lifespan bit.ly/3HRc6tX
🔬 Talk by Laura Formentini (UAM, Spain): What makes our muscles efficient at using fats for energy? It turns out a newly discovered protein team—or metabolon—could hold the key. Here’s what we learned about CoQ, mitochondria, and metabolism. 🧵 #11thConferenceICQ10A
Mitochondrial clonal mosaicism encodes a biphasic molecular clock of aging | Nature Aging nature.com/articles/s4358…
💡Our paper on probabilistic alignment of networks has been highlighted by Nature Communications as one the 50 best papers recently published in the area of Applied physics and mathematics nature.com/collections/hj… 📰Read the paper nature.com/articles/s4146…
Pharmaceutical companies like @EliLillyandCo (w bimagrumab) explore ActRIIA/B inhibitors to combat muscle loss in cancer, aging, and weight-loss (e.g., @novonordisk’s Wegovy). Our new study shows quite complex metabolic effects of these inhibitors 😵💫 biorxiv.org/content/10.110…
No us perdeu la 33a reunió de la xarxa @MetNet_Bcn el proper 20 de juny a la seu de @iec.cat
#Trobada 33è MetNet | On es fomenta l’intercanvi d’idees sobre la regulació metabòlica i el seu impacte en malalties com l’obesitat, la diabetis, patologies cardiovasculars, neurodegeneratives i el càncer. 🔗Per a més informació i inscripcionshttps://tuit.cat/dPqCR
Of interest!
Our most comprehensive review ever, now out in print. Hopefully a good ressource for many. Great collaboration with Phil Bilan and Amira Klip.
Preprint Alert We present the most comprehensive, time-resolved atlas of the human proteomic response to acute exercise. We mapped 10,000+ proteins across plasma, saliva & urine—3,000+ changed after just one workout. doi.org/10.1101/2025.0… Explore cbmr-rmpp.shinyapps.io/exerome/
Emerging role of mitochondrial calcium levels in cellular senescence and in switching cell fates | Nature Aging nature.com/articles/s4358…