Lu Chen
@luchenlab_FCCC
Assistant Professor http://luchenlab.org @foxchasecancer @CeiFccc studying RNA biology in diseases; trainings @ScienceStowers and @Stanford.
Our paper made it to the cover art of current NAR: we revealed a crosstalk between 5′ cap methylation & 3′ processing of snRNAs essential to motor neuron survival in 4 organisms. These cutesy snakes are indebted to the only @DrawImpacts @FoxChaseCancer academic.oup.com/nar/issue/50/21
wow, are we just stepped into a new era in human history?
In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by @US_FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,…
LuChenLab of @FoxChaseCancer @CeiFccc making noises at the 2025 Cold Spring Harbor meeting @cshlmeetings #cshltelo - satisfying to see Greg and Alex' work receiving wider recognition and feedback and them thriving in the incredible soil of @CSHL
Our review epub @CSHLPress. Great ride led by Luis Batista @WashUHematology & by @CeiFccc @FoxChaseCancer contributing to an understanding of telomerase RNP - the immortality enzyme hijacked by 85% cancers and the untapped "fountain of youth" for aging diseases.…
What a triumphant and compassionate moment for science. What a speech by the patient and @davidrliu and this is truly a moment that transcends life.
Last night I was honored to receive the 2025 #BreakthroughPrize in the Life Sciences, reflecting the efforts of many students, collaborators, doctors, and patients in labs around the world. I hope this 4-minute excerpt can inspire when science needs public support more than ever.
Pleasure to host Prof. Allen Nicholson from @TempleUniv with @DNAmyWhitaker @RolandDunbrack and Sid Balachandran for a super clarifying seminar and productive visit today at @FoxChaseCancer. Audience questions kept sprinkling in throughout Allen's seminar and it got extended…
Gregory Matveev, our star master student, has been selected for a podium talk in the upcoming telomere/telomerase meeting at the Cold Spring Harbor Laboratory @CSHL- a rare golden opportunity for trainees. Here is Greg presenting his work to @CeiFccc @FoxChaseCancer. He is…
Our star high school scholar Arushi Vignesh won the 1st place in the Chester County Science Fair 2025, with her work "Visualizing the Activity of Telomerase in ALT Cells". @CeiFccc @FoxChaseCancer @teschools Arushi is a rising college freshman, coming to us from Conestoga High…
Excited to see Grigory discuss his research in @luchenlab_FCCC @CeiFccc @FoxChaseCancer in the #NuclearDynamicsCancerProgram Super to see trainees lead program meetings at our @theNCI Designated Center.
#CEI2025Symp @CeiFccc @FoxChaseCancer presents key awards- 1. @institut_curie & @CeiFccc #Epigenetics Course awardees 2. C. David Allis Travel Awards- congrats to the 7 winners, especially our lab member Chloe! 3. Mentor awardee- @luchenlab_FCCC
Pround of our stellar graduate student Alex Morris @TempleUniv @CeiFccc @FoxChaseCancer presenting part of his thesis work in #cei2025symp.
NIH-supported basic biomedical research is the ROOTs of the tree of the biopharmaceutical industry (lifesaving while in trillion$). With the late Friday evening tweet by @NIH, the entire root system is being severed to its core, and there won't be leaves, flowers, or any fruits…
It's not "breaking news" now, since it was announced by NIH yesterday. But it is breaking....... washingtonpost.com/health/2025/02…
The indiscriminate and ill-conceived slashing of indirects by the @NIH yesterday must be amended if want to restore America’s leadership role biomedical research. 15% simply isn’t enough for institutions to provide the basic infrastructure needed to run a successful lab. I say…
We are pleased to announce registration for RNA 2025 - the 30th Annual Meeting of the RNA Society - is now open! www2.rnasociety.org This year’s meeting will be held at the beautiful Town and Country Resort & Convention Center in sunny San Diego, California, USA from May…
Social DNAing has been a super-productive forum - our presentation has since received great numbers of helpful feedbacks and interactions from the nucleic acids and molecular condensate communities. Thanks @zha_lab, Jaewon Min and Jean Gautier @Columbia, for hosting and the…
Thank the rising stars for outstanding webinars. This week, Dr. Lu Chen will join Social DNAing to discuss aging-associated chromatin changes. Please sign up at cancer.columbia.edu/research/progr…
Alexander D. Morris, our one and only cell-to-peak/dry-wet combo, escalated to PhD candidacy status @templemedschool in Jan 2025 - a much-desired turn of a new page and hopefully a strong momentum for new milestones soon to follow @FoxChaseCancer @CeiFccc #proudPI #NextGenPI 🥳👍
Thank the rising stars for outstanding webinars. This week, Dr. Lu Chen will join Social DNAing to discuss aging-associated chromatin changes. Please sign up at cancer.columbia.edu/research/progr…
Lori Rink @Lori_Rink shares valuable interview tips and the discovery that drew her into translational science of GIST - a rare type of stroma from the GI system. She also highlights the power of team science and the collaborative environment at @FoxChaseCancer #FridayScienceClub
