lorenzopasquali
@lorenzpasquali
Research professor @UPFBarcelona genetics and regulatory genomics, islet and chromatin but also father, travelling, campervan, sailing, handbike and kayaking.
Now it is official, @Pasquali_Lab and Lickert Lab will collaborate on understanding mechanisms of autoimmune-endocrine cell interactions for insulin-producing beta cell protection! Thanks to Lorenzo for leading this great project and @CaixaResearch for funding 😀🎉🍾
En la diabetis tipus I, una malaltia crònica autoimmune, les cèl·lules beta del pàncreas productores d’insulina són destruïdes, cosa que dona lloc a greus complicacions. 🛡️ Amb el suport de #CaixaResearch, @lorenzpasquali vol establir les bases per crear cèl·lules beta…
Esta investigación cuenta con el apoyo de #CaixaResearch y es llevada a cabo por un consorcio formado por: 👉@Pasquali_Lab, de @UPFBarcelona 👉@LickertHeiko, de @HelmholtzMunich
En la diabetes de tipo 1, una enfermedad crónica autoinmune, las células beta del páncreas productoras de insulina son destruidas, lo que da lugar a graves complicaciones. 🛡️ Con el apoyo de #CaixaResearch, @lorenzpasquali busca sentar las bases para crear células beta…
Job alert: Interested in pancreatic beta cells, a dash of genomics and novel treatment options for diabetes? We are looking for a post-doc!! Contact us for an informal chat! edzz.fa.em3.oraclecloud.com/hcmUI/Candidat…
Looking to set up your own lab? Or already have an established lab and open to move? Diabetes is one of the research priorities of UoB!! Please get in touch if interested! @DUK_research
We're delighted to announce the next cycle of recruitment for our 125th Anniversary Fellows and Chairs is now open! If you are an academic with a strong portfolio of global-leading research, we want to hear from you. Check out our vacancies and apply now: fellowsandchairs.birmingham.ac.uk/?utm_campaign=…
📣 Next week @HMar_research & @upfbiomed #ScientificSeminar are back! 🗣️ Mario Cáceres (@cacereslab - @HMar_research) and Lorenzo Pasquali (@Pasquali_Lab - @UPFBarcelona) will be the speakers of this second session of double seminars. 📆 Oct 24 ⏰12 h 📌Charles Darwin Room
🔥Hot paper from new investigators unmasks potential roles of specific ductal populations in pancreas regeneration and exocrine pathogenesis 🔗 ow.ly/z0Nt50TFCBL 🖋️ @TxellRovira @LabRovira @DuctalvsAcinar @Pasquali_Lab
Finally out the printed version of our single cell atlas of the entire murine ductal tree gastrojournal.org/article/S0016-… Followed by a really nice editorial from Rohit Chandwani gastrojournal.org/article/S0016-… Thanks to all the collaborators @DuctalvsAcinar @lorenzpasquali @miltenyibiotec
We are hiring! Looking for a computational and an experimental #predoc to work on an exciting regulatory genomics project. Enthusiastic multidisciplinary team, amazing environment @the_prbb @UPFbiomed endoregulatorygenomics.org/positions/
Thanks for highlighting our work now out @CellGenomics
A compendium of aberrant cis-regulatory elements affecting the function and fate of β cells in their progression to insulinomas and a framework to identify coding and noncoding driver mutations @CellGenomics cell.com/cell-genomics/…
Implications of noncoding regulatory functions in the development of insulinomas dlvr.it/TBvq6L
We open a PhD position in our lab @UPFbiomed , if you like exploring never studied #fungi, understanding #biophysical principles that rule the limits of life, you like fancy #microscopy...then apply, we are looking for you! (RT appreciated:-) upf.edu/documents/2869…
1/4 🧬 A study led by UPF and published in @CellGenomics reveals that #insulinomas, rare pancreatic beta cell #tumors, form due to epigenetic changes causing overexpression of oncogenes and insulin-related genes. Learn more: 👉🏾 tuit.cat/c6wZZ
Great work from @Pasquali_Lab 👇👇👇
Thrilled to share our latest publication @cellgenomics, exploring the activation of aberrant noncoding regulatory functions involved in the development of insulin-secreting neuroendocrine pancreatic tumors. cell.com/cell-genomics/…
Implications of noncoding regulatory functions in the development of insulinomas dlvr.it/T93m0G
Thrilled to share our latest publication @cellgenomics, exploring the activation of aberrant noncoding regulatory functions involved in the development of insulin-secreting neuroendocrine pancreatic tumors. cell.com/cell-genomics/…
Great to reconnect with @1jorgeferrer, @lorenzpasquali, and @TxellRovira during my visit to @CRGenomica! Huge thanks to Jorge for inviting me to present our lab's work @ifibyne. Excited about starting new and thrilling collaborations!
Exited to share our new preprint characterizing murine ductal heterogeneity at single cell resolution coupled with organoid forming capacity and differentiation potentail of novel identified ductal populations. Stay tune for the follow up in human and in novel in vivo models. 👇
A single-cell atlas of the murine pancreatic ductal tree identifies novel cell populations with potential implications in pancreas ... biorxiv.org/cgi/content/sh… #biorxiv_cellbio
Delighted to share our publication on the critical role of #m6A as an adaptive safeguard mechanism in pancreatic β-cells during Type 1 Diabetes (T1D) onset. #DiabetesResearch @NatureCellBio nature.com/articles/s4155… Here's a concise thread to highlight key findings:
It was a massive group effort with @OmicsPNNL @rmirmira @MirmiraLab @lorenzpasquali @LabLaskin @BurnumJohnson @cevansmo @sciencePNNL @PNNLab @IUSweetTweets @BarbaraDavisCtr @PurdueChemistry