Hanjin Liu
@liu_hanjin
PhD in biophysics. Interested in microtubule dynamics and MAPs. Cryo-ET, fluorescence microscopy and programming. (he/him). @liu-hanjin.bsky.social
Running RELION on laptop CPU is hell (due to a temporary server problem)
Nice! AlphaFold3 server added interactive pAE and chain division! Including option to download MSA. (Just noticed this when doing a tutorial today!)
Reusing ImageJ ROI files in napari! Please check the latest napari-roi-manager plugin😊 github.com/hanjinliu/napa…
Windows has come a long way! Relion 5.0 compiled fine in the WSL-2 and now runs natively in Windows.... Very cool! #cryoem
It’s kinda crazy but we reported over 300 plasmids and this is one of my favorite sections in the paper. Did it with @Morihideponn and @samuelhking. We will keep doing the same. If you can code, please start using QUEEN. If not, we will share something really cool shortly.
CloneSelect published in @NatureBiotech. Please check out this GIFtorial. This retrospective clone isolation method using CRISPR base editors is a powerful tool in broad biology. A history of @soh__i in @yachielab. nature.com/articles/s4158… @SBME_UBC @UTokyo_Rcast @WPI_PRIMe
A quick not too serious thread of figures on my recent Nature paper Functional connectomics dataset spanning multiple areas of cortex Fig 1: what's in the microns dataset nature.com/articles/s4158…
Our new paper is out @ScienceAdvances👇 science.org/doi/10.1126/sc… 🧬Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live human cells. 🔍@katsu_s_minami et al.have developed a chromatin behavior atlas within the nucleus. 1/2
Hey ChimeraX users! ChimeraX-CliX now supports color preview, quick menubar/toolbar search, and many other powerful features to support you. If you are interested in, please download the latest version -> cxtoolshed.rbvi.ucsf.edu/apps/chimeraxc…
A new Fast, three-dimensional, live-cell super-resolution imaging with multiplane structured illumination microscopy with new image capture procedure and new reconstruction algorithm! A really fast 3D-SIM system! Hooray to Xiaoshuai and Junchao! rdcu.be/eb0bF
"himena" is an *infinitely extensible* application for data science I made recently. github.com/hanjinliu/hime… You can open any data, integrate any widget, and your plugin will look as if it is a built-in function. Attached GIF shows my own plugin "himena-image" 👉
Hi ChimeraX users! CliX, the intelligent command line interface, now works very nicely with the system dark theme! Check it out -> cxtoolshed.rbvi.ucsf.edu/apps/chimeraxc…
What is the difference between a growing and shortening microtubule end? I thought I knew the answer until I started talking to @maxotubule and @KalutskiyMaksim. Turns out the key are protofilament clusters - check out our preprint for details biorxiv.org/content/10.110…
Thrilled to share our new work @biorxivpreprint: biorxiv.org/content/10.110… Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live cells. We reveal genome chromatin is essentially replicated from regions with greater nucleosome motions. 1/2
I started using cryosparc this week, and its Ui is just so nice 🤗
.@JagerLeanne, @psirez et al. @Bijvoet_Centre show that compacted and expanded microtubule lattice spacings coexist within cells and that #microtubules recognized by a marker for stable microtubules are predominantly expanded. hubs.la/Q02SXVbD0
Huge Congratulations to @BruggemanEzra and all others, her latest work on single-molecule orientation imaging published in @naturemethods. Huge Effort. Many thanks for @rita_strack for facilitating. @ChemCambridge nature.com/articles/s4159…
Posted our new paper about optical control of microtubule accumulation and dispersion on bioRxiv! biorxiv.org/content/10.110…