Shen Lab
@lab_shen
Bacteria enthusiasts, connoisseurs of diterpene, enediyne, and leinamycin-type natural products.
We’re hiring postdocs in the Shen Lab! We're seeking candidates with expertise in: 🧪 Natural product discovery 🧬 Genome mining ⚗️ Synthetic chemistry & biocatalysis (esp. for ADCs) Interested? Email Professor Shen with your CV + references: 🔗 explore.jobs.ufl.edu/en-us/job/5213…
By combining a soil microbe’s natural cancer-killing compound with an antibody, Wertheim UF Scripps scientists may have found a new approach to treating aggressive blood cancers including B cell #lymphoma. wertheim.scripps.ufl.edu/2025/07/02/ant… #drugdiscovery #cancer #cancerreseach
Our lab at FSU in sunny Florida is looking to hire a fully funded postdoc position in natural products discovery and/or biosynthesis in Actinobacteria! We utilize new strategies and modern synthetic biology tools to unlock new chemistry and molecules. kalkreuterlab.com
Checkout the JIMB issue on Natural Products academic.oup.com/jimb/pages/spe… Thank you authors! @marnixmedema @GillesvanWezel Michael Smanski, @BK_KAIST @hanzyduzit @lab_shen Dong-Chan Oh, @EustaquioLab @gerryiidr Hsiao-Ching Lin, Yousong Ding, @LabRudolf @ParkinsonLab and Ikuro Abe!
Many want a batch download option and we'll implement this in future releases. In the meantime, if you'd like to download all the available NPDC genomes for your analyses, you can use the following: github.com/chevrettelab/n… Just be sure to cite us :) biorxiv.org/content/10.110…
We are thrilled to release over 1,000 more genomes on the NPDC Genome Portal (npdc.rc.ufl.edu)!
We are thrilled to release over 1,000 more genomes on the NPDC Genome Portal (npdc.rc.ufl.edu)!

Discover the Natural Products Discovery Center, home to thousands of rare microbes. Learn how @UFScripps' Dr. Ben Shen & his team explore microbes for groundbreaking treatments & cures.🌿🔬 The future of drug discovery might lie in these tiny, yet mighty, microbes!
It's out! One of @tyler_alsup_'s PhD projects is now published in @rsc_chembio! He used heterologous expression to decipher the first four steps of phenalinolactone #diterpene #biosynthesis. More from Tyler coming soon! pubs.rsc.org/en/content/art…
We're thrilled to announce an update to the NPDC Portal, now featuring search and sort functionalities! This improvement was made possible thanks to our collaborators at the Chevrette Lab. @wildtypeMC npdc.rc.ufl.edu/home

We're enhancing the NPDC portal with exciting new features! While we work on this, the portal will experience some downtime. Thanks for your patience—stay tuned for the updated release!
At @UFScripps and @lab_shen, a labyrinth of vials makes up the Natural Products Discovery Center, home to a treasure trove of biodiversity with untold promise for treating disease. Read more about the living library at bit.ly/3KLqjGU.
We're excited to have our NPDC Actinobacteria collection featured in Florida Physician! This resource holds immense potential for drug discovery, and we're looking forward to what comes next. floridaphysician.med.ufl.edu/2024/05/16/a-l…
We are thrilled to release 3,000+ more genomes on the NPDC Genome Portal (npdc.rc.ufl.edu)! This week, we are also launching new filter and search functionalities to improve your experience. Please take a moment to fill out our NPDC survey here: forms.office.com/r/6yWxZDVwwQ

I once was asked: what's the one paper you are most proud of? And this is it (for now 😉). Bringing this massive amount of data into one concise storyline was a challenge which definitly broadened my scientific horizon. cell.com/chem/fulltext/…
Early Announcement! simbhq.org/np/ Together with Brad @BradMoore_SIO, Jaclyn @JMWinterlab, and Alessandra @EustaquioLab, We look forward to welcoming you to the 2025 @SIMB_Microbio Natural Product meeting at San Diego! Keynote speaker Prof. Jennifer Doudna! @doudna_lab
Buenos Días from our wonderful #SBNP24 group here in sunny Cancun! We’re off to a great start with lots of exciting talks still to come, not forgetting our Poster Session, Snorkelling trip & Gala Dinner💃🏻🍹
Congratulations Dr. Chen @AnnyChe77788549 on your amazing defense!! Very proud to have you as our lab’s 1 of 2 first Ph.D.’s! A big thanks to her committee members @DanNomura @KodadekThomas @Michael_A_Erb @lab_shen