kpircs
@kpircs
Junior Group leader at HCEMM-Semmelweis University and at Lund University
.@Fresno_State Ali Dadawalla '24 @semmelweishu attended @EMBOevents Astrocytes workshop in Venice and presented his #Fulbright project research investigating astrocytic autophagy during aging via direct reprogramming of healthy patient-derived fibroblasts meetings.embo.org/event/25-astro…
New preprint from our lab! Great collaboration with the labs of Karolina Pircs and Csaba Kerepesi from Budapest. We built molecular aging clocks for the human brain using single-nuclei RNA-seq data. doi.org/10.1101/2025.0…
In our latest preprint, we introduce the first human cell-type-specific brain aging clocks from high-precision postmortem samples. Using single-cell transcriptomics, we uncover distinct aging patterns and new insights into neurodegeneration. #BrainAging biorxiv.org/content/10.110…
“Ten years ago I was kicked out and forced to retire.” Our new medicine laureate Katalin Karikó (@kkariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges. Ten years ago, Karikó was still doing all her…
New preprint from our lab. We asked if LINE-1 transposable elements are expressed in the human brain – and found something exciting and intriguing: L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification biorxiv.org/content/10.110… Thread👇
Wonderful Swedish christmas dinner with @ParmarLab @ch_douse @kpircs @stemcellab. Celebrating outstanding success in 2022!
Swedish Medical Products Agency grants approval for clinical study of new stem cell based Parkinson’s Disease treatment: bit.ly/3yVd3Kz #parkinsons #parkinsonsdisease #medicine @Cambridge_Uni @ParmarLab @MichaelJFoxOrg
Get new insights about #autophagy in neurons derived from #Huntington's patients’ skin cells! Read the paper in @Brain1878 by @JakobssonLab @ParmarLab @Alifeinscience @raquelgarza95 @Lund_Stem @Medfak_LU #CRISPR #neuroscience #neuralreprogramming doi.org/10.1093/brain/…
This was a truly amazing collaboration between many labs, including @ParmarLab, @PDandHDLab, @kpircs, @JakobssonLab and @Ottossonlab. Thank you all for your contributions!
Researchers reprogram human skin cells to aged neurons to study neurodegenerative disorders sciencedaily.com/releases/2022/…
A small text in Swedish about our HD research lu.se/artikel/ny-for…
The proofed version of recent study using reprogrammed neurons to study HD and autophagy is now online. Enjoy!! academic.oup.com/brain/advance-…
Exciting new work on microRNA-alterations in Huntington's disease. Proud to have played a minor role in this study. A unique human dataset. actaneurocomms.biomedcentral.com/articles/10.11…
Short commentary about autophagy and HD 🧠
Wrote a commentary about autophagy and Huntingtons disease together with @PDandHDLab and @kpircs. Enjoy! tandfonline.com/doi/full/10.10…
Great opportunity. Great PI. Great Place!
Join our new lab in Lund 🇸🇪! We are looking for a postdoc to lead cool projects on mechanisms of chromatin regulation in human brain development, with a healthy sprinkle of #transposons. Lots of opportunities to learn, develop and drink coffee… Pls RT jobrxiv.org/job/lund-unive…
Pircs et al. reveal specific deficits in autophagy in induced neurons from elderly Huntington’s disease patients, providing a rationale for autophagy activation therapies. bit.ly/3pZlwIx
A mini-review on human endogenous retroviruses in @CellCellPress by me and @M_Vincendeau. Enjoy! cell.com/cell/fulltext/…