Wei Tian
@jksrtw
Proud to be part of these collective efforts and really grateful for the wonderful colleagues and fruitful collaborations. Congrats to everyone~
In 21 papers across Science, @ScienceAdvances, and @ScienceTM, researchers with the #BICCN consortium present an atlas of the human and nonhuman primate brain in unprecedented detail. The results uncover the genetic organization of the human brain. scim.ag/4ro
Excited to share this very nice work led by @zengqiurui from @JoeEcker Lab on brain aging with spatiotemporal multi-omics.
Why are older individuals more prone to neurodegenerative diseases? Very excited to share our new #bioRxiv from @JoeEcker. We study age-related epigenetic changes in the brain, highlighting on cell-type-specific transposon demethylation and TAD remodeling. We also present a deep…
check this out: CASTpFold 3D protein structure characterization + AlphaFold. academic.oup.com/nar/advance-ar…
New preprint! I'm very excited to share my work in Ecker lab! The story titled "Epigenome erosion in Alzheimer's disease brain cells and induced neurons" was a great journey with many collaborative efforts brought together from @JoeEcker lab and Gage lab. biorxiv.org/content/10.110…
very excited to share this tool for efficiently storing and operating single cell DNA methylation data. It saves ~55% storage compared to previously format and of course the storage cost $$$!
BAllC and BAllCools: Efficient Formatting and Operating for Single-Cell DNA Methylation Data biorxiv.org/cgi/content/sh… #biorxiv_bioinfo
BAllC and BAllCools: Efficient Formatting and Operating for Single-Cell DNA Methylation Data biorxiv.org/cgi/content/sh… #biorxiv_bioinfo
Our latest! Single nucleus mouse brain atlas of >110,00 DNA methylomes- many cool observations incl spatial gradients! Kudos to our @salkinstitute @UCSD @NIMHgov Center for BRAIN Epigenomics & leads Hanqing Liu & Jingtian Zhou biorxiv.org/content/10.110…
New preprint from our brain cell types team! It's a cross-species comparison of cell types in the primary motor cortex. Using high-throughput transcriptomics and epigenomics, the team profiled the nuclei of nearly half-a-million cells. Find the study here: biorxiv.org/content/10.110…
Sign up for Nature Briefing for a chance to win one of five shockingly soft Nature-branded pigs, tucked into its own rather special canvas tote bag. 🐷 The perfect accessory for the Year of the Pig!
Eliminate the bi-annual time change caused by Daylight Savings Time wh.gov/fh4k