Jonathan Kagan
@jkagan1
Scientist at Boston Children's Hospital, Professor of Pediatrics at Harvard Medical School, Husband, Father.
MyD88 cell biology explored in yeast. The fantastic @VictorJCid and colleagues reveal an unexpected variety of organelles MyD88 can bind in budding yeast. Kudos to all authors on this exciting finding. link.springer.com/article/10.100…
For MyD88 lovers... Out today! The first article out of Elba del Val's superb PhD thesis at @unicomplutense. A small step for one woman, a big step for our research on yeast-based SynBio models to understand human innate immune signaling pathways! link.springer.com/10.1007/s00018…
meetings.embo.org/event/25-immun…… -Website is OPEN for registrations. #CellDeath, #Innateimmunity, and #Autophagy. Please retweet. @EMBO @India_Alliance @ccmb_csir @CSIR_IND @ThiruKanneganti @SandhyaGansan @keshu_VRimmCh @sriram_varahan
We are excite d to have our new paper out: Tethering of the pathogen sensor caspase-4 to the endomembrane damage sensor galectin-8 poises the host to rapidly detect pathogens that breach the endolysosomal network. cell.com/cell-reports/f… @uconnresearch @uconnhealth 1/2
Beyond excited to share our #NewPaper in @CellCellPress! Inflamed environments acidify intracellular pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of inflammation. #inflammation #pH authors.elsevier.com/sd/article/S00…
#EpigeneticPower! Our #NewPaper @ImmunityCP shows that endogenous oxidized lipids decide whether host survives or dies during #sepsis, #ARDS, or Staph infection! Ox lipids bind & inhibit #AKT, boosting inhibitory H3K27 methylation via EZH2, blocking #IL10! authors.elsevier.com/a/1lS0g3qNrU-i…
Read Pukkila-Worley, MD, is the new director of the MD/PhD program: direc.to/n8PN Dr. Pukkila-Worley has mentored dozens of MD/PhD graduate students since joining @UMassChan in 2014. The @RPWLab studies host-pathogen interactions and bacterial pathogenesis. @UMassMDPhD
How Harvard Medical School and industry scientists revolutionized cancer treatment
Share your #cancer #immunology research w/ #CSCancerImmunity2025 organizers Ignacio Melero @unav, Ira Mellman @parkerici, Fabiola Rivas, @ImmunityCP & Montse Rojo de la Vega @Cancer_Cell. Abstract deadline July 25 hubs.li/Q03tjRTh0
I'm excited to start at @UCCancerCenter as chair of the Ben May Dept for Cancer Research and the @Ludwig_Cancer of UChicago! Things are moving already & we launched a faculty search for tumor microenvironment--take a look & apply! apply.interfolio.com/169039
I Symposium of Synthetic Biology in Human Health - RCCHU Study Group | Real Colegio Complutense rcc.harvard.edu/event/i-sympos…
Honored to be recognized as one of the 2025 #GreatImmigrants by @CarnegieCorp - as an advocate and an immunologist! @YaleIBIO @YaleCII @ImmunologyAAI
Want to learn how we can use mRNA to cure cancer? I discuss this topic and more with Drug Discovery World. Thanks to the fantastic Megan Thomas for a terrific interview. @corner_tx @DDWJournal #mRNA #immunotherapy #CancerResearch ddw-online.com/in-conversatio…
We’re thrilled to welcome Dr. Carla Rothlin(@carlarothlin) as our new Director of the Center for Immunology and Dr. Sourav Ghosh as CFI Program director, Immunology of Tissue Resolution, Repair, & Regeneration at UMN! Both join us from Yale and officially start in August 2025.
#Cytokines & #gut #inflammation, what’s better?! 😉 Join us tomorrow @FOCISimmunology #focis2025, 8am at the @CytokineSociety symposium!
Want to know how mRNAs can be used to program tumor immunity? Join us tomorrow at FOCIS. @FOCISimmunology #focis2025 @corner_tx linkedin.com/posts/corner-t…